Aza-Michael Addition of Amines to Activated Alkenes Catalyzed by Silica Supported Perchloric Acid Under a Solvent-Free Condition

Title: Aza-Michael Addition of Amines to Activated Alkenes Catalyzed by Silica Supported Perchloric Acid Under a Solvent-Free Condition

Volume: 4 Issue: 1

Author(s): Chinmoy Mukherjee and Anup Kumar Misra

Affiliation:

Keywords: Aza-Michael addition, amines, synthetic methods, electron-deficient alkenes, HClO4-SiO2, solvent-free

Abstract: An efficient aza-Michael addition of amines to a series of α,β-unsaturated ketones, carboxylic esters, nitriles and chalcones has been carried out using perchloric acid supported over silica gel (HClO4-SiO2) at room temperature in high yields under solvent-free reaction conditions.

Cite this article as:

Mukherjee Chinmoy and Misra Anup Kumar, Aza-Michael Addition of Amines to Activated Alkenes Catalyzed by Silica Supported Perchloric Acid Under a Solvent-Free Condition, Letters in Organic Chemistry 2007; 4 (1) . https://dx.doi.org/10.2174/157017807780037414