Synthesis of Dispiro [Flavanone/Chromanone/Tetralone]-Pyrrolo[1,2-a] Isoquinolinespiro[3.2]Acenaphthen-1-One Systems Through Three Component 1,3-Dipolar Cycloaddition Reaction

Title: Synthesis of Dispiro [Flavanone/Chromanone/Tetralone]-Pyrrolo[1,2-a] Isoquinolinespiro[3.2]Acenaphthen-1-One Systems Through Three Component 1,3-Dipolar Cycloaddition Reaction

Volume: 3 Issue: 12

Author(s): Jayadevan Jayashankaran, Rathna Durga R.S. Manian and Raghavachary Raghunathan

Affiliation:

Keywords: 1,3-dipole, quinolines, flavanone, chromanone, tetralone, azomethine ylide

Abstract: The cycloaddition reaction of non-stabilized azomethine ylides towards (E)-3-arylidene-4- flavanone, (E)-3- arylidene-4-chromanone and (E)-2-arylidene-1-tetralone as dipolarophiles has been investigated. High degree of regioselectivity has been observed in the synthesis of a new class of functionalised dispiroheterocyclic compound containing dispiro pyrrolo-isoquinoline and acenaphthequinone framework.

Cite this article as:

Jayashankaran Jayadevan, Durga R.S. Manian Rathna and Raghunathan Raghavachary, Synthesis of Dispiro [Flavanone/Chromanone/Tetralone]-Pyrrolo[1,2-a] Isoquinolinespiro[3.2]Acenaphthen-1-One Systems Through Three Component 1,3-Dipolar Cycloaddition Reaction, Letters in Organic Chemistry 2006; 3 (12) . https://dx.doi.org/10.2174/157017806779468022