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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Convenient Preparation of Original Vinylic Chlorides with Antiparasitic Potential in Quinoline Series

Author(s): Pierre Verhaeghe, Pascal Rathelot, Sylvain Rault and Patrice Vanelle

Volume 3, Issue 12, 2006

Page: [891 - 897] Pages: 7

DOI: 10.2174/157017806779467997

Price: $65

Abstract

The synthesis of various original vinylic chlorides from trichloromethylated substrates in the quinoline series is described herein. This reaction takes place under mild operating conditions via a monoelectronic transfer mechanism and presents elevated yields.

Keywords: Quinoline, antiparasitic drugs, SRN1, ERC1, vinylic chloride


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