Abstract
The development of novel drugs against obesity is one of the top priorities of worldwide drug research. In recent years, it has been facilitated by the application of virtual screening methods. In this review, we give a short introduction into obesity-related protein targets and computer-aided drug design techniques. Furthermore, we highlight the most successful virtual screening studies, outline their results, and provide suggestions for future anti-obesity drug development.
Keywords: Anti-obesity drug, computer-aided drug design, ligand-based, molecular mechanisms, obesity, obesity targets, structure-based, virtual screening, screening studies
Current Medicinal Chemistry
Title: Virtual Screening Against Obesity
Volume: 18 Issue: 14
Author(s): P. Markt, S. Herdlinger and D. Schuster
Affiliation:
Keywords: Anti-obesity drug, computer-aided drug design, ligand-based, molecular mechanisms, obesity, obesity targets, structure-based, virtual screening, screening studies
Abstract: The development of novel drugs against obesity is one of the top priorities of worldwide drug research. In recent years, it has been facilitated by the application of virtual screening methods. In this review, we give a short introduction into obesity-related protein targets and computer-aided drug design techniques. Furthermore, we highlight the most successful virtual screening studies, outline their results, and provide suggestions for future anti-obesity drug development.
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Cite this article as:
Markt P., Herdlinger S. and Schuster D., Virtual Screening Against Obesity, Current Medicinal Chemistry 2011; 18 (14) . https://dx.doi.org/10.2174/092986711795656162
DOI https://dx.doi.org/10.2174/092986711795656162 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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