Abstract
Nanotechnology has provided many promising nanoplatforms for targeted cancer imaging and therapy. Among these platforms, gold nanoparticles (GNPs) play a unique role in medicine because of their excellent physical and chemical properties. To expand the applications of GNPs in medicine, amounts of targeting moieties, imaging labels, and therapeutic agents have been integrated into these particles to form multifunctionalized GNPs. In this review, we highlight recent advances of the fabrication of cancer-targeting multifunctionalized GNPs and their applications in imaging and therapy.
Keywords: Gold nanoparticles, targeting moieties, therapeutic payloads, conjugation methods, cancer imaging, cancer therapy, Nanotechnology, multifunctionalized, cancer-targeting
Current Medicinal Chemistry
Title: Cancer-Targeting Multifunctionalized Gold Nanoparticles in Imaging and Therapy
Volume: 18 Issue: 14
Author(s): P. F. Jiao, H. Y. Zhou, L. X. Chen and B. Yan
Affiliation:
Keywords: Gold nanoparticles, targeting moieties, therapeutic payloads, conjugation methods, cancer imaging, cancer therapy, Nanotechnology, multifunctionalized, cancer-targeting
Abstract: Nanotechnology has provided many promising nanoplatforms for targeted cancer imaging and therapy. Among these platforms, gold nanoparticles (GNPs) play a unique role in medicine because of their excellent physical and chemical properties. To expand the applications of GNPs in medicine, amounts of targeting moieties, imaging labels, and therapeutic agents have been integrated into these particles to form multifunctionalized GNPs. In this review, we highlight recent advances of the fabrication of cancer-targeting multifunctionalized GNPs and their applications in imaging and therapy.
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Cite this article as:
F. Jiao P., Y. Zhou H., X. Chen L. and Yan B., Cancer-Targeting Multifunctionalized Gold Nanoparticles in Imaging and Therapy, Current Medicinal Chemistry 2011; 18 (14) . https://dx.doi.org/10.2174/092986711795656199
DOI https://dx.doi.org/10.2174/092986711795656199 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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