Abstract
The review deals with recent findings regarding the association between erectile dysfunction (ED) and coronary artery disease (CAD) in patients with diabetes. Indeed recent longitudinal studies have shown that ED is able to predict future cardiovascular events not only in nondiabetic but also in diabetic patients. In addition, in diabetic patients ED seems to be strongly associated with the presence of silent CAD. The mechanism by which ED is linked to CAD seems to be the presence of endothelial dysfunction. This pathophysiological mechanism has been extensively analysed. The possible clinical usefulness of ED to identify diabetic patients with silent CAD or at particularly high cardiovascular risk has been discussed in the review. At last, the review reports current guidelines and recent data available in the literature on the treatment of ED in patients with and without CAD and on the prevention of CAD in patients with ED.
Keywords: Diabetes, Erectile dysfunction, Coronary artery disease, Silent myocardial ischemia, Hypogonadism, Hyperthyroidism, Hypothyroidism, Hyperprolactinemia, Hypertension, Endothelial Dysfunction, Atherthrombotic Disease
Current Diabetes Reviews
Title: Erectile Dysfunction and Coronary Artery Disease in Patients with Diabetes
Volume: 7 Issue: 2
Author(s): Carmine Gazzaruso, Adriana Coppola and Andrea Giustina
Affiliation:
Keywords: Diabetes, Erectile dysfunction, Coronary artery disease, Silent myocardial ischemia, Hypogonadism, Hyperthyroidism, Hypothyroidism, Hyperprolactinemia, Hypertension, Endothelial Dysfunction, Atherthrombotic Disease
Abstract: The review deals with recent findings regarding the association between erectile dysfunction (ED) and coronary artery disease (CAD) in patients with diabetes. Indeed recent longitudinal studies have shown that ED is able to predict future cardiovascular events not only in nondiabetic but also in diabetic patients. In addition, in diabetic patients ED seems to be strongly associated with the presence of silent CAD. The mechanism by which ED is linked to CAD seems to be the presence of endothelial dysfunction. This pathophysiological mechanism has been extensively analysed. The possible clinical usefulness of ED to identify diabetic patients with silent CAD or at particularly high cardiovascular risk has been discussed in the review. At last, the review reports current guidelines and recent data available in the literature on the treatment of ED in patients with and without CAD and on the prevention of CAD in patients with ED.
Export Options
About this article
Cite this article as:
Gazzaruso Carmine, Coppola Adriana and Giustina Andrea, Erectile Dysfunction and Coronary Artery Disease in Patients with Diabetes, Current Diabetes Reviews 2011; 7 (2) . https://dx.doi.org/10.2174/157339911794940693
DOI https://dx.doi.org/10.2174/157339911794940693 |
Print ISSN 1573-3998 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6417 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Ventricular Arrhythmias in Patients with Obstructive Sleep Apnea
Current Cardiology Reviews Inflammation Fueling Atrial Fibrillation Substrate: Seeking Ways to "Cool" the Heart
Medicinal Chemistry Effects of Hydrogen-rich Water on the PI3K/AKT Signaling Pathway in Rats with Myocardial Ischemia-reperfusion Injury
Current Molecular Medicine Modulation of Cardiac and Hepatic Cytochrome P450 Enzymes During Heart Failure
Current Drug Metabolism Peptide5 Attenuates rtPA Related Brain Microvascular Endothelial Cells Reperfusion Injury via the Wnt/β-Catenin Signalling Pathway
Current Neurovascular Research Screening of Enzyme Inhibitors from Traditional Chinese Medicine
Combinatorial Chemistry & High Throughput Screening Cardiac Protection by Volatile Anaesthetics: A Review
Current Vascular Pharmacology Meet Our Section Editor
Current Diabetes Reviews Increased Neuronal Injury in Clock Gene Per-1 Deficient-Mice after Cerebral Ischemia
Current Neurovascular Research A Comprehensive Review of the Genus Pyrola Herbs in Traditional Uses, Phytochemistry and Pharmacological Activities
Current Topics in Medicinal Chemistry PiWi RNA in Neurodevelopment and Neurodegenerative Disorders
Current Molecular Pharmacology Efficacy and Cardiovascular Safety of DPP-4 Inhibitors
Current Drug Safety Actions of Selected Cardiovascular Hormones on Arterial Stiffness and Wave Reflections
Current Pharmaceutical Design Can PET Imaging Facilitate Optimization of Cancer Therapies?
Current Pharmaceutical Design Pharmacology of Nitric Oxide: Molecular Mechanisms and Therapeutic Strategies
Current Pharmaceutical Design Editorial [Hot Topic:The Calcium-Sensing Receptor: Pathophysiology and Pharmacological Modulation(Guest Editor: Ubaldo Armato)]
Current Pharmaceutical Biotechnology Future Prospects in Anti-Platelet Therapy: A Review of Potential P2Y12 and Thrombin Receptor Antagonists
Recent Patents on Cardiovascular Drug Discovery Cardiac Tissue Engineering
Recent Patents on Regenerative Medicine Giant Cell Arteritis - Beyond the Headache
Current Rheumatology Reviews Anti-HER2 Cancer Therapy and Cardiotoxicity
Current Pharmaceutical Design