Abstract
Serial IVUS has demonstrated significant differences in intimal hyperplasia (IH) volume between drug-eluting stent (DES) and bare metal stents (BMS) in recent clinical trials. It has also been reported that IVUS is a useful tool in determining optimal DES implantation, especially for diabetes mellitus (DM) patients. Recent data have also suggested a critical role for, IVUS guidance in reduction of risk for DES thrombosis. IVUS has been invaluable in the elucidation of DES effects on the arterial wall, offering insight into the potential mechanisms of DES failure. Therefore, in this current manuscript, we review the potential benefits of intravascular ultrasound (IVUS) during drug eluting stent (DES) implantation.
Keywords: Intravascular ultrasound, drug-eluting stent
Cardiovascular & Hematological Agents in Medicinal Chemistry
Title: The Role of Intravascular Ultrasound to Guide Drug-Eluting Stents Implantation
Volume: 8 Issue: 1
Author(s): T. Nakamura, J. P. Chen, D. Panchal, T. Nguyen, S. B. King III, N. Chronos and D. Hou
Affiliation:
Keywords: Intravascular ultrasound, drug-eluting stent
Abstract: Serial IVUS has demonstrated significant differences in intimal hyperplasia (IH) volume between drug-eluting stent (DES) and bare metal stents (BMS) in recent clinical trials. It has also been reported that IVUS is a useful tool in determining optimal DES implantation, especially for diabetes mellitus (DM) patients. Recent data have also suggested a critical role for, IVUS guidance in reduction of risk for DES thrombosis. IVUS has been invaluable in the elucidation of DES effects on the arterial wall, offering insight into the potential mechanisms of DES failure. Therefore, in this current manuscript, we review the potential benefits of intravascular ultrasound (IVUS) during drug eluting stent (DES) implantation.
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Nakamura T., Chen P. J., Panchal D., Nguyen T., King III B. S., Chronos N. and Hou D., The Role of Intravascular Ultrasound to Guide Drug-Eluting Stents Implantation, Cardiovascular & Hematological Agents in Medicinal Chemistry 2010; 8 (1) . https://dx.doi.org/10.2174/187152510790796147
DOI https://dx.doi.org/10.2174/187152510790796147 |
Print ISSN 1871-5257 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6182 |
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Diabetes and hypertension are real scourges of the 21st century. It is imperative to act in order to find innovative solutions to this problem. Taking medications such as hypoglycemic and antihypertensive drugs may aggravate certain underlying comorbidities, such as chronic kidney disease and cardiovascular disease. This significant drawback therefore requires ...read more
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