Abstract
The transport mechanisms of ascorbic acid (AA) are described. The metabolism of AA and its function as an antioxidant are covered in some detail. Subsequently, indications for postoperative substitution are discussed. The supplementation of up to 300 mg of AA per day in postoperative intensive care unit patients during par-/enteral nutrition is recommended to prevent hypovitaminosis. It is not clear if this is the optimal dosage of AA in postoperative/-trauma patients. New aspects for an AA substitution are discussed.
Keywords: Vitamin C, ascorbic acid, intensive care, ICU, metabolism, trauma, operation
Current Medicinal Chemistry
Title: Ascorbic Acid in Postoperative Intensive Care Patients - Biochemical Aspects and Clinical Experience
Volume: 16 Issue: 2
Author(s): Andreas Rumelin
Affiliation:
Keywords: Vitamin C, ascorbic acid, intensive care, ICU, metabolism, trauma, operation
Abstract: The transport mechanisms of ascorbic acid (AA) are described. The metabolism of AA and its function as an antioxidant are covered in some detail. Subsequently, indications for postoperative substitution are discussed. The supplementation of up to 300 mg of AA per day in postoperative intensive care unit patients during par-/enteral nutrition is recommended to prevent hypovitaminosis. It is not clear if this is the optimal dosage of AA in postoperative/-trauma patients. New aspects for an AA substitution are discussed.
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Cite this article as:
Rumelin Andreas, Ascorbic Acid in Postoperative Intensive Care Patients - Biochemical Aspects and Clinical Experience, Current Medicinal Chemistry 2009; 16 (2) . https://dx.doi.org/10.2174/092986709787002781
DOI https://dx.doi.org/10.2174/092986709787002781 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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