Abstract
Over the past decade, use of microwave energy, to heat chemical reactants on a laboratory scale, has evolved as a well-demonstrated alternative to traditional heating. Clean chemistry, reduction in reaction times, improved yields, and applicability to wide range of reactions, greatly improved efficiency with better quality, safety and tremendous scope for automation are some of the benefits of this emerging technology. Association of biological activity with heterocyclic motifs is well known and is important from drug discovery viewpoint. This article gives an account of the recent applications of microwaves in the synthesis of biologically active heterocyclic compounds with synthesis schemes and/or comprehensive review of reaction conditions and biological importance of over 50 such applications.
Current Organic Chemistry
Title: Recent Applications of Microwaves in Synthesis of Bioactive Heterocyclic Compounds
Volume: 12 Issue: 10
Author(s): Rani Jindal and Sanjay Bajaj
Affiliation:
Abstract: Over the past decade, use of microwave energy, to heat chemical reactants on a laboratory scale, has evolved as a well-demonstrated alternative to traditional heating. Clean chemistry, reduction in reaction times, improved yields, and applicability to wide range of reactions, greatly improved efficiency with better quality, safety and tremendous scope for automation are some of the benefits of this emerging technology. Association of biological activity with heterocyclic motifs is well known and is important from drug discovery viewpoint. This article gives an account of the recent applications of microwaves in the synthesis of biologically active heterocyclic compounds with synthesis schemes and/or comprehensive review of reaction conditions and biological importance of over 50 such applications.
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Cite this article as:
Jindal Rani and Bajaj Sanjay, Recent Applications of Microwaves in Synthesis of Bioactive Heterocyclic Compounds, Current Organic Chemistry 2008; 12 (10) . https://dx.doi.org/10.2174/138527208784911842
DOI https://dx.doi.org/10.2174/138527208784911842 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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