Abstract
The hairpin structure of DNA molecules have been widely employed for a variety of biosensors and nanoscale molecular assembly applications. For example, the commonly known molecular beacons can report the presence of specific nucleic acids in homogeneous solutions with high accuracy. Recently, Smith et al. proposed to induce hairpin formation through the sequence-specific binding of a small-molecule ligand G-G mismatch. Not only did this make the control of the hairpin formation flexible, but more important the induced hairpin still keeps a high sensitivity to specific hybridization. In this paper, we simulate the working process of logical XOR gates based on induced hairpin formation.
Keywords: DNA computing, Induced hairpin formation, Logical XOR gates
Current Nanoscience
Title: Simulating the XOR Gates Based on the Induced Hairpin Formation
Volume: 4 Issue: 1
Author(s): Wenbin Liu, Xiangou Zhu, Xianghong Wang, Zhixiang Yin and Shudong Wang
Affiliation:
Keywords: DNA computing, Induced hairpin formation, Logical XOR gates
Abstract: The hairpin structure of DNA molecules have been widely employed for a variety of biosensors and nanoscale molecular assembly applications. For example, the commonly known molecular beacons can report the presence of specific nucleic acids in homogeneous solutions with high accuracy. Recently, Smith et al. proposed to induce hairpin formation through the sequence-specific binding of a small-molecule ligand G-G mismatch. Not only did this make the control of the hairpin formation flexible, but more important the induced hairpin still keeps a high sensitivity to specific hybridization. In this paper, we simulate the working process of logical XOR gates based on induced hairpin formation.
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Cite this article as:
Liu Wenbin, Zhu Xiangou, Wang Xianghong, Yin Zhixiang and Wang Shudong, Simulating the XOR Gates Based on the Induced Hairpin Formation, Current Nanoscience 2008; 4 (1) . https://dx.doi.org/10.2174/157341308783591852
DOI https://dx.doi.org/10.2174/157341308783591852 |
Print ISSN 1573-4137 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6786 |
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