Abstract
The present review summarizes findings on stress-induced cell death in the IPLB-LdFB insect cell line derived from the larval fat body of the lepidopteron Lymantria dispar. Apoptotic, oncotic and autophagic cell death have been described in these cells as a consequence of oxidative stress or ATP deprivation, and similarities between IPLB-LdFB and mammalian apoptotic pathways have been highlighted. Furthermore, starting from observations in the IPLB-LdFB cells, a link has been surmised between relevance of autophagic cell death and developmental processes in the metazoan taxa.
Keywords: IPLB-LdFB insect cell line, Apoptosis, Oncosis, Autophagic cell death
Current Pharmaceutical Design
Title: Cell Death in the IPLB-LdFB Insect Cell Line: Facts and Implications
Volume: 14 Issue: 2
Author(s): D. Malagoli
Affiliation:
Keywords: IPLB-LdFB insect cell line, Apoptosis, Oncosis, Autophagic cell death
Abstract: The present review summarizes findings on stress-induced cell death in the IPLB-LdFB insect cell line derived from the larval fat body of the lepidopteron Lymantria dispar. Apoptotic, oncotic and autophagic cell death have been described in these cells as a consequence of oxidative stress or ATP deprivation, and similarities between IPLB-LdFB and mammalian apoptotic pathways have been highlighted. Furthermore, starting from observations in the IPLB-LdFB cells, a link has been surmised between relevance of autophagic cell death and developmental processes in the metazoan taxa.
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Cite this article as:
Malagoli D., Cell Death in the IPLB-LdFB Insect Cell Line: Facts and Implications, Current Pharmaceutical Design 2008; 14 (2) . https://dx.doi.org/10.2174/138161208783378752
DOI https://dx.doi.org/10.2174/138161208783378752 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
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