Drug Design Reviews - Online (Discontinued)


Role of Secondary Alcohol Metabolites in Anthracycline Cardiotoxicity: from Hypotheses to New Drugs

Volume:2   Issue: 4
Pp: 267-276
Emanuela Salvatorelli, Giorgio Minotti and Pierantonio Menna
DOI: 10.2174/1567269054087604

Computer-Aided Drug Design: Structure-Activity Relationships of Delta Opioid Ligands

Volume:2   Issue: 4
Pp: 277-291
Denzil Bernard, Andrew Coop and Alexander D. MacKerell Jr.
DOI: 10.2174/1567269054087596

Compounds that Combine Aldose Reductase Inhibitory Activity and Ability to Prevent the Glycation (Glucation and/or Fructation) of Proteins as Putative Pharmacotherapeutic Agents

Volume:2   Issue: 4
Pp: 293-304
Vassilis J. Demopoulos, Nazlaa Zaher, Chariklia Zika, Costas Anagnostou, Edouard Mamadou, Polyxeni Alexiou and Ioannis Nicolaou
DOI: 10.2174/1567269054087631

Leucine-Rich Repeats (LRRs): Structure, Function, Evolution and Interaction with Ligands

Volume:2   Issue: 4
Pp: 305-322
Norio Matsushima, Purevjav Enkhbayar, Masakatsu Kamiya, Mitsuru Osaki and Robert H. Kretsinger
DOI: 10.2174/1567269054087613

Nucleic Acid-Based Gene-Silencing Molecules as Potential Antiviral Therapeutics

Volume:2   Issue: 4
Pp: 323-333
Ji Yuan, Zhongbin Chen, Paul Cheung, David Chau and Decheng Yang
DOI: 10.2174/1567269054087640