Drug Metabolism Letters

Editor-in-Chief:

Zhiyang Zhao
Alliance Pharma
Malvern, PA
USA

Back

Become EABM
Become Reviewer

Most Cited Article

Utility of Pooled Cryopreserved Human Enterocytes as an In vitro Model for Assessing Intestinal Clearance and Drug-Drug Interactions

Volume:12   Issue:1
Pp: 3-13
Susan Wong, Utkarsh Doshi, Peter Vuong, Ning Liu, Suzanne Tay, Hoa Le, Mika Kosaka, Jane R. Kenny, Albert P. Li and Zhengyin Yan*
DOI: 10.2174/1872312812666171213114422

Cytochrome P450 3A4 Induction: Lumacaftor versus Ivacaftor Potentially Resulting in Significantly Reduced Plasma Concentration of Ivacaftor open access plus

Volume:12   Issue:1
Pp: 71-74
Elena K. Schneider*
DOI: 10.2174/1872312812666180328105259

Evaluation of Herb-Drug Interaction of Synacinn™ and Individual Biomarker through Cytochrome 450 Inhibition Assay

Volume:12   Issue:1
Pp: 62-67
Nur Syukriah Ab Rahman, Fadzilah Adibah Abd Majid*, Mohd Effendy Abd Wahid, Ain Nabihah Zainudin, Siti Nurazwa Zainol, Hassan Fahmi Ismail, Tet Soon Wong, Nirbhay Kumar Tiwari, Sanjeev Giri and Vijaya Bhargava
DOI: 10.2174/1872312812666180314112457

Genistein Affects Expression of Cytochrome P450 (CYP450) Genes in Hepatocellular Carcinoma (HEPG2/C3A) Cell Line open access plus

Volume:12   Issue:2
Pp: 138-144
Sandra R. Lepri, Daniele Sartori, Simone C. Semprebon*, Adrivanio Baranoski, Giuliana C. Coatti and Mario S. Mantovani
DOI: 10.2174/1872312812666180709150440

Comparison of Rat and Human Pulmonary Metabolism Using Precision-cut Lung Slices (PCLS) open access plus

Volume:13   Issue:1
Pp: 53-63
Yildiz Yilmaz*, Gareth Williams, Markus Walles, Nenad Manevski, Stephan Krähenbühl and Gian Camenisch
DOI: 10.2174/1872312812666181022114622

Effect of Aqueous Extract of Azadirachta indica Leaves on Pharmacokineics and Pharmacodynamics of Glipizide open access plus

Volume:13   Issue:1
Pp: 19-24
Sugandha Chaudhari*, Shitalkumar Zambad and Mohammed Ali
DOI: 10.2174/1872312812666181106115247

Hepatic Flavin-containing Monooxygenase and Aldehyde Oxidase Activities in Male Domestic Pigs at Different Ages open access plus

Volume:12   Issue:2
Pp: 125-131
Steven X. Hu*
DOI: 10.2174/1872312812666180913145334

Effects of Tobacco Nicotine-Derived Nitrosamine Ketone (NNK) Exposures on Brain Alcohol Metabolizing Enzyme Activities

Volume:12   Issue:2
Pp: 117-124
Emine B. Yalcin, Ming Tong, Gina Gallucci and Suzanne M. de la Monte*
DOI: 10.2174/1872312812666180611115418

In Vitro Drug-Drug Interaction Potential of Sulfoxide and/or Sulfone Metabolites of Albendazole, Triclabendazole , Aldicarb, Methiocarb, Montelukast and Ziprasidone open access plus

Volume:12   Issue:2
Pp: 101-116
Poonam Giri, Lakshmikant Gupta, Sneha Naidu, Vipul Joshi, Nirmal Patel, Shyamkumar Giri and Nuggehally R. Srinivas*
DOI: 10.2174/1872312812666180816164626

LC-MS/MS Identification and Structural Characterization of Main Biodegradation Products of Nitroproston - A Novel Prostaglandin-based Pharmaceutical Compound

Volume:12   Issue:1
Pp: 54-61
Natalia V. Mesonzhnik*, Natalia E. Moskaleva, Ksenia M. Shestakova, Ksenya O. Kurynina, Pavel A. Baranov, Natalia M. Gretskaya, Igor V. Serkov, Igor I. Lyubimov, Vladimir V. Bezuglov and Svetlana A. Appolonova
DOI: 10.2174/1872312812666180309160927

“Branched Tail” Oxyquinoline Inhibitors of HIF Prolyl Hydroxylase: Early Evaluation of Toxicity and Metabolism Using Liver-on-a-chip open access plus

Volume:13   Issue:1
Pp: 45-52
Andrey A. Poloznikov*, Sergey V. Nikulin, Arpenik A. Zakhariants, Anna Y. Khristichenko, Dmitry M. Hushpulian, Ildar N. Gazizov, Vladimir I. Tishkov and Irina G. Gazaryan
DOI: 10.2174/1872312813666181129100950

Formation of a Toxic Quinoneimine Metabolite from Diclofenac: A Quantum Chemical Study open access plus

Volume:13   Issue:1
Pp: 64-76
Muthusamy Ramesh* and Prasad V. Bharatam
DOI: 10.2174/1872312812666180913120736

Use of Cocktail Probe Drugs for Indexing Cytochrome P450 Enzymes in Clinical Pharmacology Studies – Review of Case Studies open access plus

Volume:13   Issue:1
Pp: 3-18
Poonam Giri, Harilal Patel and Nuggehally R. Srinivas*
DOI: 10.2174/1872312812666181119154734

Unequal Absorption of Radiolabeled and Nonradiolabeled Drug from the Oral Dose Leads to Incorrect Estimates of Drug Absorption and Circulating Metabolites in a Mass Balance Study open access plus

Volume:13   Issue:1
Pp: 37-44
Ryan H. Takahashi*, Jae H. Chang, Jodie Pang, Xiaorong Liang and Shuguang Ma
DOI: 10.2174/1872312813666181129162237

Transport of Bupropion and its Metabolites by the Model CHO and HEK293 Cell Lines open access plus

Volume:13   Issue:1
Pp: 25-36
Lyrialle W. Han, Chunying Gao, Yuchen Zhang, Joanne Wang and Qingcheng Mao*
DOI: 10.2174/1872312813666181129101507

Preface promotion: free to download

Volume:13   Issue:1
Pp: 2-2
Suresh Balani
DOI: 10.2174/187231281301190430103757

A Novel In vitro Experimental System for the Evaluation of Enteric Drug Metabolism: Cofactor-Supplemented Permeabilized Cryopreserved Human Enterocytes (MetMax™ Cryopreserved Human Enterocytes) open access plus

Volume:12   Issue:2
Pp: 132-137
Albert P. Li*, Kirsten Amaral and Ming-Chih D. Ho
DOI: 10.2174/1872312812666180820142141

Quantitative Proteomics Reveals Changes in Transporter Protein Abundance in Liver, Kidney and Brain of Mice by Pregnancy open access plus

Volume:12   Issue:2
Pp: 145-152
Michael Z. Liao, Chunying Gao, Deepak Kumar Bhatt, Bhagwat Prasad and Qingcheng Mao*
DOI: 10.2174/1872312812666180625122810

Using LC Retention Times in Organic Structure Determination: Drug Metabolite Identification open access plus

Volume:12   Issue:2
Pp: 93-100
William L. Fitch*, Cyrus Khojasteh, Ignacio Aliagas and Kevin Johnson
DOI: 10.2174/1872312812666180802093347

Alam K et al. (2018) Drug Metabolism Letters; 12, 24-32. promotion: free to download

Volume:12   Issue:2
Pp: 153-153
Tristan M. Sissung, Cindy Chau, Douglas K. Price and William D. Figg*
DOI: 10.2174/1872312812999180724145725

Alam K et al. (2018) Drug Metabolism Letters; 12, 24-32. promotion: free to download

Volume:12   Issue:2
Pp: 153-153
Tristan M. Sissung, Cindy Chau, Douglas K. Price and William D. Figg*
DOI: 10.2174/1872312812999180724145725

Effect of CYP2D6 Poor Metabolizer Phenotype on Stereoselective Nebivolol Pharmacokinetics

Volume:12   Issue:1
Pp: 68-70
Carolina P. Vieira, Daniel V. Neves, Eduardo B. Coelho and Vera Lucia Lanchote*
DOI: 10.2174/1872312812666180420104945