Drug Metabolism Letters


Zhiyang Zhao
Alliance Pharma
Malvern, PA


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Articles Ahead of Print

Imatinib Uptake into Cells is Not Mediated by Organic Cation Transporters OCT1, OCT2, or OCT3, But is Influenced by Extracellular pH

Jaurès Blanc Mettral, Nicolas Faller, Sandra Cruchon, Loïc Sottas, Thierry Buclin, Laurent Schild, Eva Choong, Aimable Nahimana and Laurent A. Decosterd*

A Practical Perspective on the Evaluation of Small Molecule CNS Penetration in Drug Discovery

Liyue Huang*, Mary C. Wells and Zhiyang Zhao

Effect of Aqueous Extract of Azadirachta indica Leaves on Pharmacokinetics and Pharmacodynamics of Glipizide

Sugandha Chaudhari*, Shitalkumar Zambad and Mohammed Ali

“Branched Tail” Oxyquinoline Inhibitors of HIF Prolyl Hydroxylase: Early Evaluation of Toxicity and Metabolism Using Liver-on-a-chip

Andrey A. Poloznikov*, Sergey V. Nikulin, Arpenik A. Zakhariants, Anna Yu. Khristichenko, Dmitry M. Hushpulian, Ildar N. Gazizov, Vladimir I. Tishkov and Irina G. Gazaryan

Transport of Bupropion and its Metabolites by the Model CHO and HEK293 Cell Lines

Lyrialle W. Han, Chunying Gao, Yuchen Zhang, Joanne Wang and Qingcheng Mao*

Use of Cocktail Probe Drugs for Indexing Cytochrome P450 Enzymes in Clinical Pharmacology Studies – Review of Case Studies

Poonam Giri, Harilal Patel and Nuggehally R Srinivas*

Unequal Absorption of Radiolabeled and Nonradiolabeled Drug from the Oral Dose Leads to Incorrect Estimates of Drug Absorption and Circulating Metabolites in a Mass Balance Study

Ryan H Takahashi*, Jae H Chang, Jodie Pang, Xiaorong Liang and Shuguang Ma

Comparison of Rat and Human Pulmonary Metabolism Using Precisioncut Lung Slices (PCLS)

Yildiz Yilmaz*, Gareth Williams, Markus Walles, Nenad Manevski, Stephan Krahenbuhl and Gian Camenisch

Formation of a Toxic Quinoneimine Metabolite from Diclofenac: A Quantum Chemical Study

M Ramesh* and Prasad V. Bharatam