Drug Metabolism Letters


Zhiyang Zhao
Alliance Pharma
Malvern, PA


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Formation/Fate of Reactive Metabolites from General Anesthetics and A Comparison of Toxic and Non-Toxic Analogues: A DFT Study

Volume:6   Issue: 4
Pp: 221-234
Sonam Bhatia, Vaibhav A. Dixit, Harish Jangra and Prasad V. Bharatam
DOI: 10.2174/1872312811206040001

Pharmacokinetic Profile of A New Diclofenac Prodrug without Gastroulcerogenic Effect

Volume:6   Issue: 4
Pp: 235-241
Michel Leandro de Campos, Helen Mariana Baldan-Cimatti, Marcelo Gomes Davanco, Marco Antonio Ferraz Nogueira, Elias Carvalho Padilha, Caroline Damico Candido, Jean Leandro dos Santos and Rosangela Goncalves Peccinini
DOI: 10.2174/1872312811206040002

Renal and Hepatic Kinetics of Tc-99m-labelled Hexakis-methoxy-isobutyl Isonitrile

Volume:6   Issue: 4
Pp: 242-246
Sabina Dizdarevic, Mark Aplin, Nicola Ryan, Stephen G. Holt, Lawrence Goldberg, Kenneth A. Miles and A. Michael Peters
DOI: 10.2174/1872312811206040003

The Evaluation of CYP2B6 Inhibition by Artemisinin Antimalarials in Recombinant Enzymes and Human Liver Microsomes

Volume:6   Issue: 4
Pp: 247-257
Therese Ericsson, Collen Masimirembwa, Angela Abelo and Michael Ashton
DOI: 10.2174/1872312811206040004

Development of Flavone Propargyl Ethers as Potent and Selective Inhibitors of Cytochrome P450 Enzymes 1A1 and 1A2

Volume:6   Issue: 4
Pp: 275-284
Jayalakshmi Sridhar, Jamie Ellis, Patrick Dupart, Jiawang Liu, Cheryl L. Stevens and Maryam Foroozesh
DOI: 10.2174/1872312811206040007

A Transcellular Assay to Assess the P-gp Inhibition in Early Stage of Drug Development

Volume:6   Issue: 4
Pp: 285-291
Jan-Shiang Taur, Edgar L. Schuck and Nancy Y. Wong
DOI: 10.2174/1872312811206040008