Drug Metabolism Letters


Zhiyang Zhao
Alliance Pharma
Malvern, PA


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An Estimate of the Number of Hepatocyte Donors Required to Provide Reasonable Estimates of Human Hepatic Clearance from In Vitro Experiments

Volume:1   Issue: 2
Pp: 91-95
James Byers, Kenneth Bachmann, Heather Eng, Anand Katta, Donald White, Ritwik Ghosh, Nicola J. Hewitt, Paul Silber and Genfu Chen
DOI: 10.2174/187231207780363660

A Glucuronidation Pathway of Capecitabine Occurs in Rats but Not in Mice and Humans

Volume:1   Issue: 2
Pp: 101-107
F. Desmoulin, C. Claparols, D. Bon, G. Larrieu, R. Martino and M. Malet-Martino
DOI: 10.2174/187231207780363615

The Human Sperm Glutathione System: A Key Role in Male Fertility and Successful Cryopreservation

Volume:1   Issue: 2
Pp: 121-126
Marcos Meseguer, Jose Antonio Martinez-Conejero, Lourdes Muriel, Antonio Pellicer, Jose Remohi and Nicolas Garrido
DOI: 10.2174/187231207780363633

Application of Simple Mathematical Expressions to Relate Half-Lives of Drugs in Mice to Those in Humans

Volume:1   Issue: 2
Pp: 127-129
Kenneth Bachmann, Jonathan Chupka, Paul Erhardt and Donald White
DOI: 10.2174/187231207780363606

Intracellular Delivery of Nanogel-Quantum Dot Hybrid Nanoparticles into Human Periodontal Ligament Cells

Volume:1   Issue: 2
Pp: 131-135
Tomoe Fukui, Hiroaki Kobayashi, Urara Hasegawa, Toshiyuki Nagasawa, Kazunari Akiyoshi and Isao Ishikawa
DOI: 10.2174/187231207780363570

Resin-Salve from Norway Spruce - A Potential Method to Treat Infected Chronic Skin Ulcers?

Volume:1   Issue: 2
Pp: 143-145
Arno Sipponen, Merja Rautio, Janne J. Jokinen, Tapio Laakso, Pekka Saranpaa and Jouni Lohi
DOI: 10.2174/187231207780363598

The Utility of Stable Cell Lines to Assess Species Differences in PXR Transactivation

Volume:1   Issue: 2
Pp: 147-152
Michael W. Sinz, Devin Pray and Judy Raucy
DOI: 10.2174/187231207780363561

Disposition of Vorinostat, A Novel Histone Deacetylase Inhibitor and Anticancer Agent, in Preclinical Species

Volume:1   Issue: 2
Pp: 153-161
Punam Sandhu, Paul A. Andrews, Maribeth P. Baker, Kenneth A. Koeplinger, Eric D. Soli, Thomas Miller and Thomas A. Baillie
DOI: 10.2174/187231207780363642

Frequency of CYP1A2 Polymorphism in Beagle Dogs

Volume:1   Issue: 2
Pp: 163-165
Valerie J. Whiterock, Terrye A. Delmonte, Lester E. Hui, Tami L. Orcutt and Michael W. Sinz
DOI: 10.2174/187231207780363688