Drug Metabolism Letters


Zhiyang Zhao
Alliance Pharma
Malvern, PA


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Most Cited Article

Clinical Confirmation that the Selective JAK1 Inhibitor Filgotinib (GLPG0634) has a Low Liability for Drug-drug Interactions

Volume:10   Issue:1
Pp: 38-48
Florence Namour*, Julie Desrivot, Annegret Van der Aa, Pille Harrison, Chantal Tasset and Gerben van`t Klooster
DOI: 10.2174/1872312810666151223103353

Non-Clinical Disposition and Metabolism of DM1, a Component of Trastuzumab Emtansine (T-DM1), in Sprague Dawley Rats

Volume:9   Issue:2
Pp: 119-131
Ben-Quan Shen, Daniela Bumbaca, Qin Yue, Ola Saad, Jay Tibbitts, S. Cyrus Khojasteh and Sandhya Girish
DOI: 10.2174/1872312809666150602151922

Ontogeny of Human Conjugating Enzymes

Volume:9   Issue:2
Pp: 99-108
Michael W.H. Coughtrie
DOI: 10.2174/1872312809666150602151213

Human HepaRG Cells can be Cultured in Hanging-drop Plates for Cytochrome P450 Induction and Function Assays promotion: free to download

Volume:9   Issue:1
Pp: 3-7
Norie Murayama, Takashi Usui, Nicky Slawny, Christophe Chesne and Hiroshi Yamazaki
DOI: 10.2174/1872312809666150119104806

In Vitro Evaluation of Reversible and Time-Dependent Inhibitory Effects of Kalanchoe crenata on CYP2C19 and CYP3A4 Activities promotion: free to download

Volume:9   Issue:1
Pp: 48-62
Charles Awortwe, Vamshi K. Manda, Cristina Avonto, Shabana I. Khan, Ikhlas A. Khan, Larry A. Walker, Patrick J. Bouic and Bernd Rosenkranz
DOI: 10.2174/1872312809666150119110200

Efficiency in Drug Discovery: Liver S9 Fraction Assay As a Screen for Metabolic Stability open access plus

Volume:10   Issue:2
Pp: 83-90
Samantha J. Richardson, April Bai, Ashutosh A. Kulkarni and Mehran F. Moghaddam
DOI: 10.2174/1872312810666160223121836

Downregulation of Hepatic Carbonyl Reductase Type 1 in End-Stage Renal Disease

Volume:9   Issue:2
Pp: 111-118
Osama Y. Alshogran, Bradley L. Urquhart and Thomas D. Nolin
DOI: 10.2174/1872312809666150818111626

Strong Induction of Cytochrome P450 1A/3A, But not P450 2B, in Cultured Hepatocytes from Common Marmosets and Cynomolgus Monkeys by Typical Human P450 Inducing Agents

Volume:10   Issue:4
Pp: 244-253
Shotaro Uehara, Yasuhiro Uno, Takako Suzuki, Takashi Inoue, Masahiro Utoh, Erika Sasaki and Hiroshi Yamazaki*
DOI: 10.2174/1872312810666161114144412

Elucidating the Mechanism of Tofacitinib Oxidative Decyanation

Volume:10   Issue:2
Pp: 136-143
Hoa Le, Peter W. Fan, Susan Wong, Shuguang Ma, James P. Driscoll, Cornelis E.C.A. Hop and S. Cyrus Khojasteh
DOI: 10.2174/1872312810666160427104954

Gender Difference of Hepatic and Intestinal CYP3A4 in CYP3AHumanized Mice Generated by a Human Chromosome-engineering Technique

Volume:11   Issue:1
Pp: 60-67
Kaoru Kobayashi*, Chihiro Abe, Mika Endo, Yasuhiro Kazuki, Mitsuo Oshimura and Kan Chiba
DOI: 10.2174/1872312811666170404153804