CNS & Neurological Disorders - Drug Targets

(Formerly Current Drug Targets - CNS & Neurological Disorders)


Cesar V. Borlongan
Department of Neurosurgery and Brain Repair
University of South Florida Morsani College of Medicine
Tampa, FL


Become EABM
Become Reviewer

Conference Report (3rd GTC Congress Report on Ubiquitin & Drug Discovery Feb 25-26, Palms Casino Resort, Las Vegas, NV, USA) promotion: free to download

Volume:12   Issue: 3
Pp: 295-297
Hari Shanker Sharma and Aruna Sharma
DOI: 10.2174/1871527311312030001

Commentary (Research Highlights: Linking Productive Autophagy to Neuroprotection: Potential Implications for Anti-Ischemic Therapy) promotion: free to download

Volume:12   Issue: 3
Pp: 298-299
G.K. Rajanikant and Sinoy Sugunan
DOI: 10.2174/1871527311312030002

Editorial (Hot Topic: Neuroprotection Against Stroke and CNS Injury: New Mechanisms, Targets, and Controversies) promotion: free to download

Volume:12   Issue: 3
Pp: 300-301
Rehana K. Leak and Jun Chen
DOI: 10.2174/1871527311312030003

Biphasic Mechanisms of Neurovascular Unit Injury and Protection in CNS Diseases

Volume:12   Issue: 3
Pp: 302-315
Takakuni Maki, Kazuhide Hayakawa, Loc-Duyen D. Pham, Changhong Xing, Eng H. Lo and Ken Arai
DOI: 10.2174/1871527311312030004

HSP27 Protects the Blood-Brain Barrier Against Ischemia-Induced Loss of Integrity open access plus

Volume:12   Issue: 3
Pp: 325-337
Rehana K. Leak, Lili Zhang, R. Anne Stetler, Zhongfang Weng, Peiying Li, G. Brandon Atkins, Yanqin Gao and Jun Chen
DOI: 10.2174/1871527311312030006

Age-Dependent Microglial Activation in Immature Brains After Hypoxia- Ischemia

Volume:12   Issue: 3
Pp: 338-349
Peter Ferrazzano, Vishal Chanana, Kutluay Uluc, Emin Fidan, Erinc Akture, Douglas B. Kintner, Pelin Cengiz and Dandan Sun
DOI: 10.2174/1871527311312030007

Ischemic Post-Conditioning Partially Reverses Cell Cycle Reactivity Following Ischemia/Reperfusion Injury: A Genome-Wide Survey

Volume:12   Issue: 3
Pp: 350-359
Haiping Zhao, Yumin Luo, Xiangrong Liu, Rongliang Wang, Feng Yan, Xiaomeng Liu, Sijie Li, Rehana K. Leak and Xunming Ji
DOI: 10.2174/1871527311312030008

TrkB Receptor Agonist 7, 8 Dihydroxyflavone Triggers Profound Gender- Dependent Neuroprotection in Mice After Perinatal Hypoxia and Ischemia

Volume:12   Issue: 3
Pp: 360-370
Kutluay Uluc, Pınar Kendigelen, Emin Fidan, Louise Zhang, Vishal Chanana, Douglas Kintner, Erinc Akture, Chihwa Song, Keqiang Ye, Dandan Sun, Peter Ferrazzano and Pelin Cengiz
DOI: 10.2174/18715273113129990061

Drug-Induced Hypothermia in Stroke Models: Does it Always Protect?

Volume:12   Issue: 3
Pp: 371-380
Meijuan Zhang, Haiying Wang, Jinbing Zhao, Cong Chen, Rehana K. Leak, Yun Xu, Peter Vosler, Jun Chen, Yanqin Gao and Feng Zhang
DOI: 10.2174/1871527311312030010

miR-15b Suppression of Bcl-2 Contributes to Cerebral Ischemic Injury and is Reversed by Sevoflurane Preconditioning

Volume:12   Issue: 3
Pp: 381-391
Hong Shi, Bao-liang Sun, Jia Zhang, Shiduo Lu, Pengyue Zhang, Hailian Wang, Qiong Yu, R. Anne Stetler, Peter S. Vosler, Jun Chen and Yanqin Gao
DOI: 10.2174/1871527311312030011

Adhesion Molecules in CNS Disorders: Biomarker and Therapeutic Targets

Volume:12   Issue: 3
Pp: 392-404
Qingyi Ma, Sheng Chen, Damon Klebe, John H. Zhang and Jiping Tang
DOI: 10.2174/1871527311312030012

The Battle of the Sexes for Stroke Therapy: Female- Versus Male-Derived Stem Cells

Volume:12   Issue: 3
Pp: 405-412
Yuji Kaneko, Mibel M. Pabon, Travis Dailey, Nathan L. Weinbren, Jessica Rizzi, Cyrus Tamboli, Julianne Vasconcellos, Nicole Kuzmin-Nichols, Paul R. Sanberg, David J. Eve, Naoki Tajiri and Cesar V. Borlongan
DOI: 10.2174/1871527311312030013

Neurorestorative Effect of Urinary Bladder Matrix-Mediated Neural Stem Cell Transplantation Following Traumatic Brain Injury in Rats open access plus

Volume:12   Issue: 3
Pp: 413-425
J.Y. Wang, A.K.F. Liou, Z.H. Ren, L. Zhang, B.N. Brown, X.T. Cui, S.F. Badylak, Y.N. Cai, Y.Q. Guan, Rehana K. Leak, J. Chen, X. Ji and L. Chen
DOI: 10.2174/1871527311312030014

Does Mechanism of Drug Action Matter to Inform Rational Polytherapy in Epilepsy?

Volume:12   Issue: 3
Pp: 426-435
Giorgia Giussani and Ettore Beghi
DOI: 10.2174/1871527311312030015

Inhibition of Glycogen Synthase Kinase-3 Reverses Tau Hyperphosphorylation Induced by Pin1 Down-Regulation

Volume:12   Issue: 3
Pp: 436-443
Yan-Si Xiong, Dan-Li Wang, Lu Tan, Xiong Wang, Li-Ming Chen, Cheng-Xin Gong, Jian-Zhi Wang and Ling-Qiang Zhu
DOI: 10.2174/1871527311312030016

Expression of Concern promotion: free to download

Volume:12   Issue: 3
Pp: 444-444

DOI: 10.2174/1871527311312030017