CNS & Neurological Disorders - Drug Targets

(Formerly Current Drug Targets - CNS & Neurological Disorders)

Editor-in-Chief:

Stephen D. Skaper  
Department of Pharmaceutical and Pharmacological Sciences
University of Padua
Padua
Italy

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Editor's Choice

Cerebrolysin and Aquaporin 4 Inhibition Improve Pathological and Motor Recovery after Ischemic Stroke

Volume: 17   Issue: 4
Pp: 299-308
Bogdan Catalin, Otilia-Constantina Rogoveanu, Ionica Pirici, Tudor Adrian Balseanu, Adina Stan, Valerica Tudorica, Maria Balea, Ion Mindrila, Carmen Valeria Albu, Guleed Mohamed, Daniel Pirici* and Dafin Fior Muresanu
DOI: 10.2174/1871527317666180425124340

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Inhibition of Neurogenesis by Zika Virus Infection

Volume: 17   Issue: 2
Pp: 78-86
Fahim Ahmad, Amna Siddiqui, Mohammad A. Kamal and Sayed Sartaj Sohrab*
DOI: 10.2174/1871527317666180202115114

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Implications of PEGylation of Carbon Nanotubes for Central Nervous System Bioavailability

Volume: 16   Issue: 9
Pp: 983-989
Gisele Eva Bruch, Marcos F. Cordeiro, Livia S. Gomides, Carolina Peixoto, Arthur P. Cordeiro, Lidiane Dal Bosco, Adelina P. Santos and Daniela M. Barros*
DOI: 10.2174/1871527316666170731111735

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Immunomodulatory Strategies for Huntington's Disease Treatment

Volume: 16   Issue: 8
Pp: 936-944
Gabriela D. Colpo*, Natalia P. Rocha, Erin Fur Stimming and Antonio L. Teixeira
DOI: 10.2174/1871527316666170613084801

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The Role of Innate Immune System Receptors in Epilepsy Research

Volume: 16   Issue: 7
Pp: 749-762
Jessica Cordero-Arreola, Rachel M. West, Julieta Mendoza-Torreblanca, Edna Mendez-Hernandez, Jose Salas-Pacheco, Manuel Menendez-Gonzalez, Rafael C. Freire, Sergio Machado, Eric Murillo-Rodriguez, Antonio E. Nardi and Oscar Arias-Carrion*
DOI: 10.2174/1871527316666170725145549

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Metabotropic Glutamate Receptor 7 (mGluR7) as a Target for Modulating Pain-evoked Activities of Neurons in the Hippocampal CA3 Region of Rats

Volume: 16   Issue: 5
Pp: 610-616
Xinya Wei, Dongxiao Yang, Tiefeng Shi, Jianing Wang, Yunling Deng, Xuezhu Qiao, Chunxiao Yang* and Manying Xu*
DOI: 10.2174/1871527315666160801142356

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Mitochondrial Dysfunctions in Bipolar Disorder: Effect of the Disease and Pharmacotherapy

Volume: 16   Issue: 2
Pp: 176-186
Tereza Cikankova, Ekaterina Sigitova, Martina Zverova, Zdenek Fisar, Jiri Raboch and Jana Hroudova
DOI: 10.2174/1871527315666161213110518

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Therapeutic Antibodies for Spinal Cord Injury

Volume: 16   Issue: 1
Pp: 51-64
Dan-yang Tang and Wei-jiang Zhao
DOI: 10.2174/1871527315666160915150754

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Nanomaterials for Neurology: State-of-the-Art open access plus

Volume: 15   Issue: 10
Pp: 1306-1324
María Fernanda Veloz-Castillo, Rachel M. West, Jessica Cordero-Arreola, Oscar Arias-Carrión and Miguel A. Méndez-Rojas
DOI: 10.2174/1871527315666160801144637

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Functions of Ghrelin in Brain, Gut and Liver

Volume: 15   Issue: 8
Pp: 956-963
Cristina Stasi and Stefano Milani
DOI: 10.2174/1871527315666160709203525

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Neurobiology of Bipolar Disorder: Abnormalities on Cognitive and Cortical Functioning and Biomarker Levels

Volume: 15   Issue: 6
Pp: 713-722
Alberto S. de Sá, Carlos Campos, Nuno B.F. Rocha, Ti-Fei Yuan, Flávia Paes, Oscar Arias-Carrión, Mauro G. Carta, Antonio E. Nardi, Elie Cheniaux and Sergio Machado
DOI: 10.2174/1871527315666160321111359

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Novel Lactulose and Melibiose Targeting Autophagy to Reduce PolyQ Aggregation in Cell Models of Spinocerebellar Ataxia 3

Volume: 15   Issue: 3
Pp: 351-359
Chih-Hsin Lin, Yih-Ru Wu, Jinn-Moon Yang, Wan-Ling Chen, Chih-Ying Chao, I-Cheng Chen, Te-Hsien Lin, Yi-Ci Wu, Kai-Cheng Hsu, Chiung-Mei Chen, Guan-Chiun Lee, Hsiu-Mei Hsieh-Li, Chi-Mei Lee and Guey-Jen Lee-Chen
DOI: 10.2174/1871527314666150821101522

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Development of a Novel and Robust Pharmacological Model of Okadaic Acid-induced Alzheimer’s Disease in Zebrafish promotion: free to download

Volume: 15   Issue: 1
Pp: 86-94
Shadia E. Nada, Frederick E. Williams and Zahoor A. Shah
DOI: 10.2174/1871527314666150821105602

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Nanoparticles: A Neurotoxicological Perspective

Volume: 14   Issue: 10
Pp: 1317-1327
Anuradha Pandey, Vajir Malek, Visakh Prabhakar, Yogesh Aanat Kulkarni and Anil Bhanudas Gaikwad
DOI: 10.2174/1871527314666150821112411

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A Fluorescence Resonance Energy Transfer Assay For Monitoring α- Synclein Aggregation in a Caenorhabditis Elegans Model For Parkinson’s Disease

Volume: 14   Issue: 8
Pp: 1054-1068
Archana Nagarajan, Rakesh Bodhicharla, Jody Winter, Charumathi Anbalagan, Kevin Morgan, Mark Searle, Aamir Nazir, Ademola Adenle, April Fineberg, Declan Brady, Kelly Vere, Jo Richens, Paul O'Shea, David Bell and David de-Pomerai
DOI: 10.2174/1871527314666150821110538

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Role of Pituitary Adenylate Cyclase-Activating Polypeptide in Nociception and Migraine

Volume: 14   Issue: 4
Pp: 540-553
Janos Tajti, Bernadett Tuka, Balint Botz, Zsuzsanna Helyes and Laszlo Vecsei
DOI: 10.2174/1871527314666150429114234

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TDP-43 as a Modulator of Synaptic Plasticity in a Mouse Model of Spinal Motoneuron Degeneration promotion: free to download

Volume: 14   Issue: 1
Pp: 55-60
Rosario Gulino, Stefano Forte, Rosalba Parenti and Massimo Gulisano
DOI: 10.2174/1871527314666150116115414

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Gut Emotions - Mechanisms of Action of Probiotics as Novel Therapeutic Targets for Depression and Anxiety Disorders

Volume: 13   Issue: 10
Pp: 1770-1786
Anastasiya Slyepchenko, Andre F. Carvalho, Danielle S. Cha, Siegfried Kasper and Roger S. McIntyre
DOI: 10.2174/1871527313666141130205242

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Modulation of the FGF14:FGF14 Homodimer Interaction Through Short Peptide Fragments

Volume: 13   Issue: 9
Pp: 1559-1570
Syed Ali, Alexander Shavkunov, Neli Panova, Svetla Stoilova-McPhie and Fernanda Laezza
DOI: 10.2174/1871527313666141126103309

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Poly (D,L-Lactide-co-Glycolide) Nanoparticles Loaded with Cerebrolysin Display Neuroprotective Activity in a Rat Model of Concussive Head Injury

Volume: 13   Issue: 8
Pp: 1475-1482
Barbara Ruozi, Daniela Belletti, Flavio Forni, Aruna Sharma, Dafin Muresanu, Herbert Mossler, Maria A. Vandelli, Giovanni Tosi and Hari S. Sharma
DOI: 10.2174/1871527313666140806145540

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Effects of Exercise on Anxiety and Depression Disorders: Review of Meta- Analyses and Neurobiological Mechanisms

Volume: 13   Issue: 6
Pp: 1002-1014
Mirko Wegner, Ingo Helmich, Sergio Machado, Antonio E. Nardi, Oscar Arias-Carrion and Henning Budde
DOI: 10.2174/1871527313666140612102841

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Positive Allosteric Modulators (PAMs) of Metabotropic Glutamate Receptor 5 (mGluR5) Attenuate Microglial Activation

Volume: 13   Issue: 4
Pp: 558-566
Fengtian Xue, Bogdan A. Stoica, Marie Hanscom, Shruti V. Kabadi and Alan I. Faden
DOI: 10.2174/18715273113126660199

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