CNS & Neurological Disorders - Drug Targets

(Formerly Current Drug Targets - CNS & Neurological Disorders)

Editor-in-Chief:

Cesar V. Borlongan
Department of Neurosurgery and Brain Repair
University of South Florida Morsani College of Medicine
Tampa, FL
USA

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Most Cited Article

Oxidative Stress: Major Threat in Traumatic Brain Injury

Volume:17   Issue:9
Pp: 689-695
Nidhi Khatri, Manisha Thakur, Vikas Pareek, Sandeep Kumar, Sunil Sharma and Ashok Kumar Datusalia*
DOI: 10.2174/1871527317666180627120501

Dl-3-n-Butylphthalide (NBP): A Promising Therapeutic Agent for Ischemic Stroke

Volume:17   Issue:5
Pp: 338-347
Shan Wang, Fei Ma, Longjian Huang, Yong Zhang, Yuchen Peng, Changhong Xing, Yipu Feng, Xiaoliang Wang* and Ying Peng*
DOI: 10.2174/1871527317666180612125843

Protective Effect of Kaempferol on the Transgenic Drosophila Model of Alzheimer’s Disease

Volume:17   Issue:6
Pp: 421-429
Tanveer Beg, Smita Jyoti, Falaq Naz, Rahul, Fahad Ali, Syed Kashif Ali, Ahmed Mohamed Reyad and Yasir Hasan Siddique*
DOI: 10.2174/1871527317666180508123050

The Underlying Role of Oxidative Stress in Neurodegeneration: A Mechanistic Review

Volume:17   Issue:3
Pp: 207-215
Habib Yaribeygi, Yunes Panahi*, Behjat Javadi and Amirhossein Sahebkar*
DOI: 10.2174/1871527317666180425122557

Diabetes Mellitus to Neurodegenerative Disorders: Is Oxidative Stress Fueling the Flame?

Volume:17   Issue:9
Pp: 644-653
Nandkishor K. Mule and Jitendra N. Singh*
DOI: 10.2174/1871527317666180809092359

Hydrogen Sulfide in Physiological and Pathological Mechanisms in Brain

Volume:17   Issue:9
Pp: 654-670
Mohit Kumar and Rajat Sandhir*
DOI: 10.2174/1871527317666180605072018

Neurotransplantation Therapy and Cerebellar Reserve

Volume:17   Issue:3
Pp: 172-183
Jan Cendelin, Hiroshi Mitoma* and Mario Manto
DOI: 10.2174/1871527316666170810114559

Autophagy and Mitochondria: Targets in Neurodegenerative Disorders

Volume:17   Issue:9
Pp: 696-705
Ashutosh Kumar*, Amruta Dhawan, Alknanda Kadam and Akshada Shinde
DOI: 10.2174/1871527317666180816100203

A Novel Combination of ω-3 Fatty Acids and Nano-Curcumin Modulates Interleukin-6 Gene Expression and High Sensitivity C-reactive Protein Serum Levels in Patients with Migraine: A Randomized Clinical Trial Study

Volume:17   Issue:6
Pp: 430-438
Mina Abdolahi, Payam Sarraf, Mohammad Hassan Javanbakht, Niyaz Mohammadzadeh Honarvar, Mahsa Hatami, Neda Soveyd, Abbas Tafakhori, Mohsen Sedighiyan, Mona Djalali, Arash Jafarieh, Yousef Masoudian and Mahmoud Djalali*
DOI: 10.2174/1871527317666180625101643

Cognitive Impact of Cerebellar Damage: Is There a Future for Cognitive Rehabilitation?

Volume:17   Issue:3
Pp: 199-206
Kim van Dun, Frank V. Overwalle, Mario Manto* and Peter Marien
DOI: 10.2174/1871527317666180110125043

Development of a Nasal Donepezil-loaded Microemulsion for the Treatment of Alzheimer’s Disease: in vitro and ex vivo Characterization promotion: free to download

Volume:17   Issue:1
Pp: 43-53
Lupe C. Espinoza, Marisol Vacacela, Beatriz Clares*, Maria Luisa Garcia, Maria-Jose Fabrega and Ana C. Calpena
DOI: 10.2174/1871527317666180104122347

NF-κB as a Key Mediator of Brain Inflammation in Alzheimer’s Disease

Volume:18   Issue:1
Pp: 3-10
Chul Ju Hwang, Dong-Young Choi, Mi Hee Park and Jin Tae Hong*
DOI: 10.2174/1871527316666170807130011

Therapeutic Advancement in Alzheimer Disease: New Hopes on the Horizon?

Volume:17   Issue:8
Pp: 571-589
Ajeet Singh, Abshar Hasan, Sakshi Tiwari and Lalit M. Pandey*
DOI: 10.2174/1871527317666180627122448

Therapeutic Targeting of Chemokines and Chemokine Receptors in Multiple Sclerosis: Opportunities and Challenges

Volume:17   Issue:7
Pp: 496-508
Tahereh Sadeghian-Rizi, Hossein Khanahmad and Ali Jahanian-Najafabadi*
DOI: 10.2174/1871527317666180713111100

C-Abl Inhibition; A Novel Therapeutic Target for Parkinson's Disease promotion: free to download

Volume:17   Issue:1
Pp: 14-21
Abdelrahman Ibrahim Abushouk, Ahmed Negida*, Rasha Abdelsalam Elshenawy, Hossam Zein, Ali M. Hammad, Ahmed Menshawy and Wael M.Y. Mohamed
DOI: 10.2174/1871527316666170602101538

The Yin and Yang of BK Channels in Epilepsy

Volume:17   Issue:4
Pp: 272-279
Yudan Zhu, Shuzhang Zhang, Yijun Feng, Qian Xiao, Jiwei Cheng* and Jie Tao*
DOI: 10.2174/1871527317666180213142403

Monoamine Involvement in the Antidepressant-Like Effect of β-Caryophyllene

Volume:17   Issue:4
Pp: 309-320
Danillo Ramos de Oliveira, Dayane Moreira da Silva, Iziara Ferreira Florentino, Adriane Ferreira de Brito, James Oluwagbamigbe Fajemiroye, Daiany Priscilla Bueno da Silva, Fabio Fagundes da Rocha, Elson Alves Costa and Pablinny Moreira Galdino*
DOI: 10.2174/1871527317666180420150249

The Large Conductance Calcium- and Voltage-activated Potassium Channel (BK) and Epilepsy

Volume:17   Issue:4
Pp: 248-254
Kai Zang, Yuwen Zhang, Jie Hu and Yun Wang*
DOI: 10.2174/1871527317666180404104055

Characterization of Regulatory T-Cells in Multiple Sclerosis Patients Treated with Interferon Beta-1a

Volume:17   Issue:2
Pp: 113-118
Mohsen Ebrahimimonfared, Ali Ganji, Sara Zahedi, Parisa Nourbakhsh, Keyvan Ghasami and Ghasem Mosayebi*
DOI: 10.2174/1871527317666180327122435

Non-invasive Cerebellar Stimulation in Cerebellar Disorders

Volume:17   Issue:3
Pp: 193-198
Chiara Di Nuzzo, Fabiana Ruggiero, Francesca Cortese, Ilaria Cova, Alberto Priori and Roberta Ferrucci*
DOI: 10.2174/1871527317666180404113444

Epigenetics in Neurodegenerative Diseases: The Role of Histone Deacetylases

Volume:18   Issue:1
Pp: 11-18
Sorabh Sharma, K.C. Sarathlal and Rajeev Taliyan*
DOI: 10.2174/1871527317666181004155136

Exosomal miR-214-5p Released from Glioblastoma Cells Modulates Inflammatory Response of Microglia after Lipopolysaccharide Stimulation through Targeting CXCR5

Volume:18   Issue:1
Pp: 78-87
Jian-kai Yang*, Hong-jiang Liu, Yuanyu Wang, Chen Li, Ji-peng Yang, Liang Yang, Xue-jiao Qi, Yin-long Zhao, Xue-fang Shi, Jing-chen Li, Guo-zhu Sun and Bao-hua Jiao
DOI: 10.2174/1871527317666181105112009

Amyotrophic Lateral Sclerosis and Oxidative Stress: A Double-Blind Therapeutic Trial After Curcumin Supplementation

Volume:17   Issue:10
Pp: 767-779
Lucia Chico*, Elena Caldarazzo Ienco, Costanza Bisordi, Annalisa Lo Gerfo, Lucia Petrozzi, Antonio Petrucci, Michelangelo Mancuso and Gabriele Siciliano
DOI: 10.2174/1871527317666180720162029