Current Drug Discovery Technologies

Editor-in-Chief:
Vladimir P. Torchilin
Department of Pharmaceutical Science Center
for Pharmaceutical Biotechnology and Nanomedicine
Northeastern University
Boston, MA 02115
USA

 

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Articles Ahead of Print

A Review of Pharmacological Properties and Toxicological Effects of Adiantum Capillus-veneris L.

Volume:17
Ali Kashkooe, Frough Afsari Sardari, Mahkameh Moradi Mehrabadi and Mohammad M. Zarshenas*

Evaluation of Diuretic and Antioxidant Properties in Aqueous Bark and Fruit Extracts of Pine

Volume:17
Hadi Shariati, Mohammad Hassanpour, Gholamreza Sharifzadeh, Asghar Zarban*, Saeed Samarghandian and Farhad Saeedi

Syringic Acid: A Potential Natural Compound for the Management of Renal Oxidative Stress and Mitochondrial Biogenesis in Diabetic Rats

Volume:17
Marzieh Rashedinia , Mohammad Javad Khoshnoud, Bahman khalvati Fahlyan , Seyedeh-Sara Hashemi, Mahshid Alimohammadi and Zahra Sabahi*

Review of Phytochemical Compounds as Antiviral Agents against Arboviruses from the Genera Flavivirus and Alphavirus

Volume:17
Samira Sardari, Mahmoud Rafieian-Kopaei*, Khojasteh Malekmohammad and Robert D. E Sewell

Structural And Computational Perspectives of Selectively Targeting Mutant Proteins

Volume:17
Mathew Coban, Sarah Fraga and Thomas Caulfield*

Current Development on Chitosan-based Antimicrobial Drug Formulations for the Wound Healing

Volume:17
Harekrishna Roy, Sk Abdul Rahaman, T Vinay Kumar and Sisir Nandi*

An Evidence-Based Research on Botanical Sources for Oral Mucositis Treatment in Traditional Persian Medicine

Volume:17
Fatemeh Sadat Hasheminasab, Fariba Sharififar, Seyed Mehdi Hashemi and Mohammad Setayesh*

Efficacy of Honey-based Ophthalmic Formulation in Patients with Corneal Ulcer: A Randomized Clinical Trial

Volume:17
Mahmood Nejabat, Kazem Soltanzadeh, Masoud Yasemi, Saeid Daneshamouz, Amin Reza Akbarizadeh and Mojtaba Heydari*

Evaluation of Ficus retusa L. Leaves with Special Reference to Antidiarrheal and Anti-spasmodic Activity

Volume:17
Najam Ali Khan*, Chitra Tomar, Alankar Shrivastav, Aftab Ahmad and Arun Kumar Mishra

Formulation, Standardization, and a Preliminary Before-After Clinical Trial on Effect of a Traditional Herbal Formula (Maqliasa) on Manifestations of Ulcerative Colitis

Volume:17
Meysam Shirzad, Mohammad Mahdi Ahmadian-Attari, Seyed Mohammad Sadegh Ghafoori, Leila Mohammad Taghizadeh Kashani , Mehdi Pasalar, Alireza Abbassian and Shahram Agah *

Pharmacological Applications of Phlorotannins: A Comprehensive Review

Volume:17
Ahsan Javed*, Muhammad Bilal Hussain, Ali Tahir, Marwa Waheed, Ahsan Anwar, Mohammad Ali Shariati, Sergey Plygun, Alexey Laishevtcev and Mehdi Pasalar*

The Potential Role of Tea in Periodontal Therapy: An Updated Review

Volume:17
Ali Forouzanfar, Hamideh Sadat Mohammadipour and Fatemeh Forouzanfar*

In silico-based Approach to Investigate the Ability of PEGylated Rapamycin to Inhibit Galectin-3

Volume:17
Marwan Abdelmahmoud Abdelkarim Maki, Palanirajan Vijayaraj Kumar*, Manogaran Elumalai and Omer Bayazeid

Alcoholic and Non-Alcoholic Liver Diseases: Promising Molecular Drug Targets and their Clinical Development

Volume:17
Komal Thapa, Ajmer Singh Grewal*, Neha Kanojia, Lata Rani, Neelam Sharma and Sukhbir Singh

Moringa Oleifera in Malnutrition: A Comprehensive Review

Volume:16
Bilal Sajid Mushtaq*, Muhammad Bilal Hussain, Rabia Omer, Hafiz Ahmad Toor, Marwa Waheed, Mohammad Ali Shariati, Plygun Sergey and Mojtaba Heydari

Insights into the FDA 2018 New Drug Approvals

Volume:16
Alaa Bedair and Fotouh R. Mansour*

Medicinal Plants in the Treatment of Obsessive-Compulsive Disorder: A Review

Volume:16
Ali Talaei, Fatemeh Forouzanfar* and Shahin Akhondzadeh

Influence of β-D-mannuronic Acid, As a New Member of Non-steroidal Anti- Inflammatory Drugs Family, on the Expression Pattern of Chemokines and their Receptors in Rheumatoid Arthritis

Volume:16
Mona Aslani, Arman Ahmadzadeh, Zahra Aghazadeh, Majid Zaki-Dizaji, Laleh Sharifi, Mostafa Hosseini and Abbas Mirshafiey*

Phytoextracts as Antibacterials - A Review

Volume:16
Goutam Chandra*, Devaleena Mukherjee, Anushree Singha Ray, Soroj Chatterjee and Indranil Bhattacharjee

Effective Antiviral Medicinal Plants and Biological Compounds Against Central Nervous System Infections: A Mechanistic Review

Volume:16
Khojasteh Malekmohammad, Mahmoud Rafieian-Kopaei*, Samira Sardari and Robert D. E Sewell

Kaempferol as a Potential PAK4 Inhibitor in Triple Negative Breast Cancer: Extra Precision Glide Docking and Free Energy Calculation

Volume:16
Michael A. Arowosegbe*, Oluwamuyiwa T. Amusan, Segun A. Adeola, Oluwatosin B. Adu, Israel A. Akinola, Bimpe F. Ogungbe, Olaposi I. Omotuyi, Gbemisola M. Saibu, Adewale J. Ogunleye, Ramon I. Kanmodi, Nekabari E. Lugbe, Oluwafemi J. Ogunmola, Damilola C. Ajayi, Sedoten O. Ogun, Faith O. Oyende, Ahmed O. Bello, Abudulmalik O. Ishola and Patrick E. Obasieke

Exploring Antimicrobials from the Flora and Fauna of Marine: Opportunities and Limitations

Volume:16
Krishanmoorthy Venkateskumar, Subramani Parasuraman*, Leow Yu Chuen, Veerasamy Ravichandran and Subramani Balamurgan

Targeting Small Molecule Tyrosine Kinases by Polyphenols: New Move Towards Anti-tumor Drug Discovery

Volume:16
Nikhil S. Sakle, Shweta A. More, Sachin A. Dhawale and Santosh N. Mokale*

Discovery and Development of Novel Anti-fungal Peptides Against Foodspoiling Fungi

Volume:16
Belal J. Muhialdin*, Hussein L. Algboory, Nameer K. Mohammed, Hana Kadum, Anis Shobirin Meor Hussin, Nazamid Saari and Zaiton Hassan

Interaction with Modified Cyclodextrin as a Way to Increase the Antimalarial Activity of Primaquine

Volume:16
Liliane Henrique Torres, Lucas Bragança de Carvalho, Adneia de Fátima Abreu Venceslau, Carlos Jaime and Luciana de Matos Alves Pinto*

Large-scale High-throughput Screening Revealed 5'-(carbonylamino)-2,3'- bithiophene-4'-carboxylate as Novel Template for Antibacterial Agents

Volume:16
Yan A. Ivanenkov, Renat S. Yamidanov, Ilya A. Osterman, Petr V. Sergiev, Vladimir A. Aladinskiy, Anastasia V. Aladinskaya, Victor A. Terentiev, Mark S. Veselov, Andrey A. Ayginin, Dmitry A. Skvortsov, Katerina S. Komarova, Bogdan A. Zagribelnyy*, Alexey Kh. Baimiev, Kseniya Yu. Shvetc, Andrey Kh. Baimiev, Alina A. Sofronova, Alexey E. Machulkin, Rostislav A. Petrov, Liana F. Zainullina, Marina A. Maximova, Zulfiya R. Zileeva, Yulia V. Vakhitova, Dmitry S. Bezrukov, Maria M. Puchinina and Olga A. Dontsova

Antimicrobial Peptides: An Approach to Combat Resilient Infections

Volume:16
Debaprasad Parai*, Pia Dey and Samir Kumar Mukherjee

The Effect of Viola Odorata L. Oil for Fever in Children: A Randomized Triple-blinded Placebo-controlled Clinical Trial

Volume:16
Vahid Tafazoli, Mahdi Shahriari, Mojtaba Heydari, Hosein Ali Nikbakht, Mohammad Mahdi Zarshenaas and Majid Nimrouzi*

Photochemical /Photocytotoxicity Studies of New Tetrapyrrolic Structures as Potential Candidates for Cancer Theranostics

Volume:16
L. F. Vieira Ferreira *, I. Ferreira Machado, A. Gama, R. P. Socoteanu, R. Boscencu, G. Manda, R. C. Calhelha and I. C.F.R. Ferreira

Drug Stereochemistry: A Prodigy For Pharmacology and Drug Development

Volume:16
Karan Gandhi, Umang Shah* and Sandip Patel

Hybrid Design of Isonicotinic Acid Hydrazide Derivatives: Machine Learning Studies, Synthesis and Biological Evaluation of their Antituberculosis Activity

Volume:16
Vasyl Kovalishyn, Diana Hodyna, Vitaliy O. Sinenko, Volodymyr Blagodatny, Ivan Semenyuta, Sergiy R. Slivchuk, Volodymyr Brovarets, Gennady Poda* and Larysa Metelytsia

Design, Synthesis and Anticancer Activity of Site Specific Short Chain Cationic Peptide

Volume:16
Ravi Dutt Sharma*, Jainendra Jain and Ratan Lal Khosa

Biological Significance of Imidazole-based Analogues in New Drug Development

Volume:16
Pratiksha Nishant Chopra and Jagdish Kumar Sahu*

Long-term Stabilization of Aqueous Doxycycline Formulations, in Mucoadhesive Hydrogels for Treatment of Oral Mucosal Conditions

Volume:16
Venu Gopal Reddy Patlolla, William Peter Holbrook, Sveinbjorn Gizurarson and Thordis Kristmundsdottir

Therapeutic Aspects of Squill; An Evidence-Based Review

Volume:16
Khadije Saket, Jalil Tavakol Afshari, Ehsan Saburi, Mahdi Yousefi and Roshanak Salari*

Mechanisms of Antimicrobial Resistance (AMR) and Alternative Approaches to Overcome AMR

Volume:16
Chew-Li Moo, Shun-Kai Yang, Khatijah Yusoff, Mokrish Ajat, Warren Thomas, Aisha Abushelaibi, Swee-Hua-Erin Lim and Kok-Song Lai*

Harnessing Metal Homeostasis Offers Novel and Promising Targets Against Candida albicans

Volume:16
Saif Hameed*, Sandeep Hans, Shweta Singh and Zeeshan Fatima

The Role of Anthocyanins in Drug Discovery: Recent Developments

Volume:16
Marco Bonesi*, Mariarosaria Leporini, Maria C. Tenuta and Rosa Tundis

In Vitro Protective Effect of Ascorbic Acid Against Antibiotic-Induced Hepatotoxicity

Volume:16
Veneta Simon, K V Sreerag, R Sasikumar and S K Kanthlal*

Antimicrobial Activity of Agarwood Oil Against Multiple-Drug-Resistant (MDR) Microbes of Clinical, Food and Environmental Origin

Volume:16
Bhoj Raj Singh*, Dharmendra Kumar Sinha, OR Vinodh Kumar , Prasanna Vadhana, Monika Bhardwaj, Archana Saraf, Sakshi Dubey, Abhijit M Pawde, Ujjwal Kumar De and Vinod Kumar Gupta

Hydroalcoholic Extract of Cuscuta Epithymum Enhances Pentobarbitalinduced Sleep: Possible Involvement of GABAergic System

Volume:15
Fatemeh Forouzanfar, Mohammad Mahdi Vahedi, Azita Aghaei and Hassan Rakhshandeh*

An Herbal H2 Blocker in Melasma Treatment

Volume:16
Marjan Mahjour* and Arash Khoushabi

Novel Approaches to Anti-Atherosclerotic Therapy: Cell-Based Models and Herbal Preparations (Review of Our Own Data)

Volume:16
Alexander N. Orekhov*, Andrey V. Grechko, Elena B. Romanenko, Dongwei Zhang and Dimitry A. Chistiakov

Cancer Cell Metabolism Featuring Nrf2

Volume:15
Payal Chatterjee*, Mukesh Yadav, Namrata Chauhan, Ying Huang and Yun Luo