Current Drug Discovery Technologies

Vladimir P. Torchilin
Department of Pharmaceutical Science Center
for Pharmaceutical Biotechnology and Nanomedicine
Northeastern University
Boston, MA 02115



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Editorial (Hot Topic:Emerging Technologies for the Study of Drug Metabolism and Pharmacokinetics) promotion: free to download

Volume:7   Issue: 3
Pp: 141-142
Takahiro Ochiya, Nobuyoshi Kosaka, Haruhisa Head, Section for Studies on Metastasis, National Cancer Center Research Institute, 1-1, Tsukiji, 5-chome, Chuo-ku, Tokyo 104-0045, Japan. and Yunsheng Hsieh
DOI: 10.2174/157016310793180585

Integration of Physicochemical and Pharmacokinetic Parameters in Lead Optimization: A Physiological Pharmacokinetic Model Based Approach

Volume:7   Issue: 3
Pp: 143-153
Elizabeth Hong-Geller, Sofiya N. Micheva-Viteva, Biju Benjamin, Tarani Kanta Barman, Tridib Chaira and Jyoti K. Paliwal
DOI: 10.2174/157016310793180558

Glutathione Modulation and Oxidative Stress in Human Liver Slices

Volume:7   Issue: 3
Pp: 154-169
Alison E.M. Vickers*, Robyn L. Fisher and John R. Sinclair
DOI: 10.2174/157016310793180530

The In Silico Prediction of Human-Specific Metabolites from Hepatotoxic Drugs

Volume:7   Issue: 3
Pp: 170-187
Ravouru Nagaraju, Ande Penchala Prathusha, Rajesh Kaza, Koganti Bharathi, Luis G. Valerio and Anthony Long
DOI: 10.2174/157016310793180567

Hepatocytes as a Tool in Drug Metabolism, Transport and Safety Evaluations in Drug Discovery

Volume:7   Issue: 3
Pp: 188-198
M. Akram, M. A. Iquebal, K. Naimuddin, Jasminder Sahi, Susan Grepper and Cornelia Smith
DOI: 10.2174/157016310793180576

Emerging In Vitro Tools to Evaluate Cytochrome P450 and Transporter-Mediated Drug-Drug Interactions

Volume:7   Issue: 3
Pp: 199-222
Cormac Concannon, Desmond A. Hennelly, Simon Noott, Dipak K. Sarker, Chuang Lu, Mingxiang Liao, Lawrence Cohen and Cindy Q. Xia
DOI: 10.2174/157016310793180549

Hydrophilic Interaction Liquid Chromatography-Tandem Mass Spectrometry for Drug Development

Volume:7   Issue: 3
Pp: 223-231
Andrea L.O.Hebb, Virender Bhan, Alexander D. Wishart, Craig S. Moore, George S. Robertson and Yunsheng Hsieh
DOI: 10.2174/157016310793180521