Current HIV Research


Yuntao Wu
National Center for Biodefense and Infectious Diseases
School of Systems Biology
George Mason University
Manassas, VA


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Open Access Articles

The Increase of HIV-1 Infection, Neurocognitive Impairment, and Type 2 Diabetes in The Rio Grande Valley open Access plus

Volume: 17   Issue: 6
Pp: 377-387
Roberto De La Garza, Hansapani Rodrigo, Francisco Fernandez and Upal Roy*

Frailty among HIV-1 Infected Adults under Antiretroviral Therapy in Indonesia open Access plus

Volume: 17   Issue: 3
Pp: 204-213
Wulunggono Wulunggono, Evy Yunihastuti*, Hamzah Shatri, Edy Rizal Wahyudi and Youdiil Ophinni

HIV Epidemiology and Prevention in Southwestern China: Trends from 1996-2017 open Access plus

Volume: 17   Issue: 2
Pp: 85-93
Huanhuan Chen, Liuhong Luo, Stephen W. Pan, Guanghua Lan, Qiuying Zhu, Jianjun Li, Jinhui Zhu, Yi Chen, Zhiyong Shen, Xianming Ge, Zhenzhu Tang, Hui Xing, Yiming Shao, Yuhua Ruan* and Wenmin Yang*

Molecular Characterization of HIV-1 Minority Subtypes in Hong Kong: A Recent Epidemic of CRF07_BC among the Men who have Sex with Men Population open Access plus

Volume: 17   Issue: 1
Pp: 53-64
Kenneth Siu-Sing Leung, Sabrina Wai-Chi To, Jonathan Hon-Kwan Chen, Gilman Kit-Hang Siu, Kenny Chi-Wai Chan and Wing-Cheong Yam*

Plasma Membrane Proteomic Profile Discovers Macrophage-capping Protein Related to Latent HIV-1 open Access plus

Volume: 17   Issue: 1
Pp: 42-52
Yujiao Zhang, Yinzhong Shen, Lin Yin, Tangkai Qi, Xiaofang Jia, Hongzhou Lu and Lijun Zhang*

The Pattern of Non-AIDS-defining Cancers in the HIV Population: Epidemiology, Risk Factors and Prognosis. A Review open Access plus

Volume: 17   Issue: 1
Pp: 1-12
Marco Franzetti*, Elena Ricci and Paolo Bonfanti

Antiretroviral Therapy-associated Adverse Drug Reactions and their Effects on Virologic Failure- A Retrospective Cohort Study in Nigeria open Access plus

Volume: 16   Issue: 6
Pp: 436-446
Isaac O. Abah*, Nondumiso B.Q. Ncube, Hazel A. Bradley, Oche O. AgbaJi and Phyllis Kanki

Real World Patient-reported Outcomes in HIV-infected Adults Switching to EVIPLERA®, Because of a Previous Intolerance to cART. PRO-STR Study open Access plus

Volume: 16   Issue: 6
Pp: 425-435
D. Podzamczer*, N. Rozas, P. Domingo, C. Miralles, E. Van den Eynde, A. Romero, E. Deig, H. Knobel, J. Pasquau, A. Antela, B. Clotet, P. Geijo, E. Rodríguez de Castro, M.A. Casado, A. Muñoz, A. Casado and for the PRO-STR STUDY GROUP

Assessment of Antibody Interference of Enfuvirtide (T20) Function Shows Assay Dependent Variability open Access plus

Volume: 16   Issue: 6
Pp: 404-415
Michele Smith, Jonathon Hoffman, Hakimuddin Sojar, Ravikumar Aalinkeel, Chiu-Bin Hsiao and Mark Daniel Hicar*

Potential Role of Regulatory T Cells in Mother-to-Child Transmission of HIV open Access plus

Volume: 16   Issue: 6
Pp: 396-403
Peter A. Kessler*

The Per-1 Short Isoform Inhibits de novo HIV-1 Transcription in Resting CD4+ T-cells open Access plus

Volume: 16   Issue: 6
Pp: 384-395
Li Zhao, Mei Liu, Jiayue Ouyang, Zheming Zhu, Wenqing Geng, Jinxiu Dong, Ying Xiong, Shumei Wang, Xiaowei Zhang, Ying Qiao, Haibo Ding, Hong Sun, Guoxin Liang*, Hong Shang* and Xiaoxu Han*

Molecular Antiretroviral Resistance Markers of Human Immunodeficiency Virus-1 of CRF01_AE Subtype in Bali, Indonesia open Access plus

Volume: 16   Issue: 5
Pp: 374-382
Nyoman Sri Budayanti, Tuti Parwati Merati, Budiman Bela and Gusti Ngurah Mahardika*

Dynamic Characteristics and HIV Infection of Men who have Sex with Men from 2011 to 2017 in Yinchuan, Ningxia, China open Access plus

Volume: 16   Issue: 5
Pp: 364-373
Zhong-Lan Wu*, Guang-Yu Guan, Jian-Hua Zhao*, Xue-Min Ma, Xue-Min Wang, Dong-Zhi Yang, Min Cao and Daniel J. Rawle

Tobacco and Antiretrovirals Modulate Transporter, Metabolic Enzyme, and Antioxidant Enzyme Expression and Function in Polarized Macrophages open Access plus

Volume: 16   Issue: 5
Pp: 354-363
Ying Mu, Benjamin J. Patters, Narasimha M. Midde, Hui He, Santosh Kumar and Theodore J. Cory*

Near Full-length Genomic Sequencing and Molecular Analysis of HIV-Infected Individuals in a Network-based Intervention (TRIP) in Athens, Greece: Evidence that Transmissions Occur More Frequently from those with High HIV-RNA open Access plus

Volume: 16   Issue: 5
Pp: 345-353
Evangelia-Georgia Kostaki, Daniel Frampton, Dimitrios Paraskevis, Katerina Pantavou, Bridget Ferns, Jade Raffle, Paul Grant, Zisis Kozlakidis, Andria Hadjikou, Eirini Pavlitina, Leslie D. Williams, Angelos Hatzakis, Samuel R. Friedman, Eleni Nastouli and Georgios K. Nikolopoulos*

The Spontaneous Control of HIV Replication is Characterized by Decreased Pathological Changes in the Gut-associated Lymphoid Tissue open Access plus

Volume: 16   Issue: 5
Pp: 338-344
Natalia A. Taborda, Luis A. Correa, Manuel Geronimo Feria and María T. Rugeles*

In Silico Design and Immunologic Evaluation of HIV-1 p24-Nef Fusion Protein to Approach a Therapeutic Vaccine Candidate open Access plus

Volume: 16   Issue: 5
Pp: 322-337
Mona Sadat Larijani, Seyed Mehdi Sadat, Azam Bolhassani, Mohammad Hassan Pouriayevali, Golnaz Bahramali* and Amitis Ramezani*

Prevalence of HIV in Patients with Malignancy and of Malignancy in HIV Patients in a Tertiary Care Center from North India open Access plus

Volume: 16   Issue: 4
Pp: 315-320
Sanjeev Sinha*, Ashish Agarwal, Kartik Gupta, Dibyakanti Mandal, Mitul Jain, Roger Detels, Karabi Nandy, Michelle A. DeVos, S.K. Sharma, N. Manoharan, P.K. Julka, G.K. Rath, Richard F. Ambinder and Ronald T. Mitsuyasu

HIV-specific T-cell Responses and Generalized Activation in HIV-1 Infected Long-term Non-progressors and Progressors from South India open Access plus

Volume: 16   Issue: 4
Pp: 302-314
Chinnambedu Ravichandran Swathirajan, Ramachandran Vignesh, Greer Waldrop, Uma Shanmugasundaram, Pannerselvam Nandagopal, Sunil Suhas Solomon, Amrose Pradeep, Shanmugam Saravanan and Kailapuri Gangatharan Murugavel*

Correlation of Apolipoprotein B mRNA-editing Enzyme, Catalytic Polypeptide- like 3G Genetic Variant rs8177832 with HIV-1 Predisposition in Pakistani Population open Access plus

Volume: 16   Issue: 4
Pp: 297-301
Khurshid Iqbal*, Muhammad Imran, Shafi Ullah, Muhsin Jamal and Yasir Waheed

The Effect of MSM and CD4+ Count on the Development of Cancer AIDS (AIDS-defining Cancer) and Non-cancer AIDS in the HAART Era open Access plus

Volume: 16   Issue: 4
Pp: 288-296
Prosanta Mondal, Hyun J. Lim* and OHTN Cohort Study Team

M918: A Novel Cell Penetrating Peptide for Effective Delivery of HIV-1 Nef and Hsp20-Nef Proteins into Eukaryotic Cell Lines open Access plus

Volume: 16   Issue: 4
Pp: 280-287
Bahareh Rostami, Shiva Irani, Azam Bolhassani* and Reza Ahangari Cohan

Formulation and in-vivo Evaluation of Novel Topical Gel of Lopinavir for Targeting HIV open Access plus

Volume: 16   Issue: 4
Pp: 270-279
Huda Ansari* and Prabha Singh

HIV Associated Neurodegenerative Disorders: A New Perspective on the Role of Lipid Rafts in Gp120-Mediated Neurotoxicity open Access plus

Volume: 16   Issue: 4
Pp: 258-269
Lisa K. Smith, Thomas B. Kuhn*, Jack Chen and James R. Bamburg

Sexual Roles, Risk Sexual Behaviours, and HIV Prevalence among Men who Have Sex with Men Seeking HIV Testing in Changsha, China open Access plus

Volume: 16   Issue: 2
Pp: 174-181
Yunxiao Lei, Kaili Zhang, Xueling Xiao, Chulei Tang, Xianhong Li and Honghong Wang*

Impact of Different Antiretroviral Strategies on Total HIV-DNA Level in Virologically Suppressed HIV-1 Infected Patients open Access plus

Volume: 15   Issue: 6
Pp: 448-455
Isabella Bon, Leonardo Calza, Giuseppina Musumeci, Serena Longo, Alessia Bertoldi, Vanessa D`Urbano, Davide Gibellini, Eleonora Magistrelli, Pier Luigi Viale and Maria Carla Re*

Atazanavir Plus Cobicistat: Week 48 and Week 144 Subgroup Analyses of a Phase 3, Randomized, Double-Blind, Active-Controlled Trial open Access plus

Volume: 15   Issue: 3
Pp: 216-224
Joel Gallant*, Graeme Moyle, Juan Berenguer, Peter Shalit, Huyen Cao, Ya-Pei Liu, Joel Myers, Lisa Rosenblatt, Lingfeng Yang and Javier Szwarcberg

Antibody Functional Assays as Measures of Fc Receptor-Mediated Immunity to HIV - New Technologies and their Impact on the HIV Vaccine Field open Access plus

Volume: 15   Issue: 3
Pp: 202-215
Bruce D. Wines, Hugh Billings, Milla R. Mclean, Stephen J. Kent and P. Mark Hogarth*

HIV Risk Behavior and Prevention Considerations Among Military Personnel in Three Caribbean Region Countries: Belize, Barbados, and the Dominican Republic open Access plus

Volume: 15   Issue: 3
Pp: 154-160
Nakisa Asefnia*, Lisa Cowan and Rose Werth

HIV/AIDS Securitization: Outcomes and Current Challenges open Access plus

Volume: 15   Issue: 2
Pp: 78-81
Aladdin H. Shadyab*, Braden R. Hale and Richard A. Shaffer

Effect of the Modification of p24 Peptide Antigen on Dendritic Cell Uptake and T Cell Activation open Access plus

Volume: 15   Issue: 1
Pp: 3-14
Peter L. Smith, Kirstie J. Norgate, Eve Hegarty, Nathalie Gregeda, Edward Heelas, Maja Sommerfelt, Tonnes Lange, Arnt-Ove Hovden, Birger Sorenson, Angus G. Dalgleish and Mark Bodman-Smith

Prevalence of HIV-1 Subtypes and Antiretroviral Drug Resistance Mutations in Nepal open Access plus

Volume: 14   Issue: 6
Pp: 517-524
Nirajan Bhusal, Ruengpung Sutthent*, Navin Horthongkham, Niracha Athipanyasilp and Wannee Kantakamalakul

Astrocytes as an HIV Reservoir: Mechanism of HIV Infection open Access plus

Volume: 14   Issue: 5
Pp: 373-381
Guan-Han Li, Lisa Henderson and Avindra Nath

Persistent But Not Replicating HIV-1 Cell-Associated DNA in Semen of Long-Term ART Experienced Men open Access plus

Volume: 14   Issue: 4
Pp: 316-323
Amandine Gagneux-Brunon, Dorsaf Nasri, Rachel Terrasse, Karine Sauné, Marie-Claude Gagnieu, Anne Frésard, Olivier Delezay, Jacques Izopet, Bruno Pozzetto, Frédéric Lucht and Thomas Bourlet

Cellular Antiviral Factors that Target Particle Infectivity of HIV-1 open Access plus

Volume: 14   Issue: 3
Pp: 211-216
Christine Goffinet

The Early Bird Catches the Worm – Can Evolution Teach us Lessons in Fighting HIV? open Access plus

Volume: 14   Issue: 3
Pp: 183-210
Torsten Schaller and Nikolas Herold

Perspectives of Genome-Editing Technologies for HIV Therapy open Access plus

Volume: 14   Issue: 1
Pp: 2-8
Hirotaka Ebina, Peter Gee and Yoshio Koyanagi

Effects of a Quasi-Randomized Web-Based Intervention on Risk Behaviors and Treatment Seeking Among HIV-Positive Men Who Have Sex With Men in Chengdu, China open Access plus

Volume: 13   Issue: 6
Pp: 490-496
Guodong Mi, Zunyou Wu, Xiaodong Wang, Cynthia X. Shi, Fei Yu, Tian Li, Linglin Zhang, Jennifer M. McGoogan, Lin Pang, Jie Xu and Keming Rou

Brief Messages to Promote Prevention and Detection of Sexually Transmitted Infections open Access plus

Volume: 13   Issue: 5
Pp: 408-420
Rocio Garcia-Retamero and Edward T. Cokely

Correlates of Patient Retention in HIV Care and Treatment Programs in Nigeria open Access plus

Volume: 13   Issue: 4
Pp: 300-307
Chinenye Ugoji, Nwanneka Okere, Patrick Dakum, Rukeme Ake-Uzoigwe, Donald Igboelina, Nicaise Ndembi, Ernest Ekong, Manhattan Charurat and William A. Blattner

HIV Replication at Low Copy Number and its Correlation with the HIV Reservoir: A Clinical Perspective open Access plus

Volume: 13   Issue: 3
Pp: 250-257


Implementing Implementation Science: An Approach for HIV Prevention, Care and Treatment Programs open Access plus

Volume: 13   Issue: 3
Pp: 244-249
Barrot H. Lambdin, Ben Cheng, Trevor Peter, Jessie Mbwambo, Tsitsi Apollo, Megan Dunbar, Ifeoma C. Udoh, Adithya Cattamanchi, Elvin H. Geng and Paul Volberding

Opiate Addiction Therapies and HIV-1 Tat: Interactive Effects on Glial [Ca2+]i, Oxyradical and Neuroinflammatory Chemokine Production and Correlative Neurotoxicity open Access plus

Volume: 12   Issue: 6
Pp: 424-434
Sylvia Fitting, Shiping Zou, Nazira El-Hage, Masami Suzuki, Jason J. Paris, Christina J. Schier, Jose W. Rodriguez, Myosotys Rodriguez, Pamela E. Knapp and Kurt F. Hauser

Heme Oxygenase-1 Dysregulation in the Brain: Implications for HIVAssociated Neurocognitive Disorders open Access plus

Volume: 12   Issue: 3
Pp: 174-188
Surendra S. Ambegaokar and Dennis L. Kolson

β-Catenin/TCF-4 Signaling Regulates Susceptibility of Macrophages and Resistance of Monocytes to HIV-1 Productive Infection open Access plus

Volume: 12   Issue: 3
Pp: 164-173
Yosra Aljawai, Maureen H. Richards, Melanie S. Seaton, Srinivas D. Narasipura and Lena Al-Harthi

Brain Inflammation is a Common Feature of HIV-Infected Patients without HIV Encephalitis or Productive Brain Infection open Access plus

Volume: 12   Issue: 2
Pp: 97-110
Eleonora Tavazzi, David Morrison, Peter Sullivan, Susan Morgello and Tracy Fischer

Macrophage Derived Cystatin B/Cathepsin B in HIV Replication and Neuropathogenesis open Access plus

Volume: 12   Issue: 2
Pp: 111-120
Linda E. Rivera, Krystal Colon, Yisel M. Cantres-Rosario, Frances M. Zenon and Loyda M. Melendez

Outcomes in Older Versus Younger Patients Over 96 Weeks in HIV-1– Infected Patients Treated with Rilpivirine or Efavirenz in ECHO and THRIVE open Access plus

Volume: 11   Issue: 7
Pp: 570-575
Robert Ryan, Yaswant K. Dayaram, Deborah Schaible, Bruce Coate and David Anderson

Epitope Specificity of Human Immunodeficiency Virus-1 Antibody Dependent Cellular Cytotoxicity [ADCC] Responses open Access plus

Volume: 11   Issue: 5
Pp: 378-387
Justin Pollara, Mattia Bonsignori, M. Anthony Moody, Marzena Pazgier, Barton F. Haynes and Guido Ferrari

Long-Term Gender-Based Outcomes for Atazanavir/Ritonavir (ATV/r)- Containing Regimens in Treatment-Experienced Patients with HIV open Access plus

Volume: 11   Issue: 4
Pp: 333-341
Veronica Svedhem-Johansson, Pascal Pugliese, Norbert H. Brockmeyer, Anders Thalme, Claudia Michalik, Stefan Esser, Marie-Helene Barlet, Tina Nakonz and Maria J. Jimenez-Exposito

Opiate Drug Use and the Pathophysiology of NeuroAIDS open Access plus

Volume: 10   Issue: 5
Pp: 435-452
Kurt F. Hauser, Sylvia Fitting, Seth M. Dever, Elizabeth M. Podhaizer and Pamela E. Knapp

HIV-1 Vpu Interference with Innate Cell-mediated Immune Mechanisms open Access plus

Volume: 10   Issue: 4
Pp: 327-333
Johan K. Sandberg, Sofia K. Andersson, Susanna M. Bachle, Douglas F. Nixon and Markus Moll

Sites of Action of HIV-1 Vpu in BST-2/Tetherin Downregulation open Access plus

Volume: 10   Issue: 4
Pp: 283-291
Juan F. Arias, Yukie Iwabu and Kenzo Tokunaga

Control of HIV Latency by Epigenetic and Non-Epigenetic Mechanisms open Access plus

Volume: 9   Issue: 8
Pp: 554-567
Jonathan Karn and Uri Mbonye

One Protein to Rule them All: Modulation of Cell Surface Receptors and Molecules by HIV Nef open Access plus

Volume: 9   Issue: 7
Pp: 496-504
Alessia Landi, Veronica Iannucci, Anouk Van Nuffel, Pieter Meuwissen and Bruno Verhasselt

The Nef-Infectivity Enigma: Mechanisms of Enhanced Lentiviral Infection open Access plus

Volume: 9   Issue: 7
Pp: 474-489
Jolien Vermeire, Griet Vanbillemont, Wojciech Witkowski and Bruno Verhasselt

Antiretrovirals for Prevention: Realizing the Potential. Closing Commentary by the Executive Director of UNAIDS open Access plus

Volume: 9   Issue: 6
Pp: 470-472
Michel Sidibe

Antiretroviral Therapy in Prevention of HIV and TB: Update on Current Research Efforts open Access plus

Volume: 9   Issue: 6
Pp: 446-469
Reuben Granich, Somya Gupta, Amitabh B. Suthar, Caoimhe Smyth, David Hoos, Marco Vitoria, Mariangela Simao, Catherine Hankins, Bernard Schwartlander, Renee Ridzon, Brigitte Bazin, Brian Williams, Ying-Ru Lo, Craig McClure, Julio Montaner and Gottfried Hirnschall

Universal Testing and Treatment as an HIV Prevention Strategy: Research Questions and Methods open Access plus

Volume: 9   Issue: 6
Pp: 429-445
Richard Hayes, Kalpana Sabapathy and Sarah Fidler

Costing Human Rights and Community Support Interventions as a Part of Universal Access to HIV Treatment and Care in a Southern African Setting open Access plus

Volume: 9   Issue: 6
Pp: 416-428
Louisa Jones, Paula Akugizibwe, Michaela Clayton, Joseph J. Amon, Miriam Lewis Sabin, Rod Bennett, Christine Stegling, Rachel Baggaley, James G. Kahn, Charles B. Holmes, Navneet Garg, Carla Makhlouf Obermeyer, Christina DeFilippo Mack, Phoebe Williams, Caoimhe Smyth, Marco Vitoria, Siobhan Crowley, Brian Williams, Craig McClure, Reuben Granich and Gottfried Hirnschall

Cost-Effectiveness of Antiretroviral Therapy for Prevention open Access plus

Volume: 9   Issue: 6
Pp: 405-415
James G. Kahn, Elliot A. Marseille, Rod Bennett, Brian G. Williams and Reuben Granich

Articulating A Rights-Based Approach to HIV Treatment and Prevention Interventions open Access plus

Volume: 9   Issue: 6
Pp: 396-404
David Barr, Joseph J. Amon and Michaela Clayton

The Unrealized Potential of Addiction Science in Curbing the HIV Epidemic open Access plus

Volume: 9   Issue: 6
Pp: 393-395
Nora D. Volkow, Ruben D. Baler and Jacques L. Normand

Antiretroviral Treatment as Prevention: Impact of the ‘Test and Treat’ Strategy on the Tuberculosis Epidemic open Access plus

Volume: 9   Issue: 6
Pp: 383-392
Robin Wood and Stephen D. Lawn

Modelling the Impact of Antiretroviral Therapy on the Epidemic of HIV open Access plus

Volume: 9   Issue: 6
Pp: 367-382
Brian G. Williams, Viviane Lima and Eleanor Gouws

Harnessing the Prevention Benefits of Antiretroviral Therapy to Address HIV and Tuberculosis open Access plus

Volume: 9   Issue: 6
Pp: 355-366
Reuben Granich, Ying-Ru Lo, Amitabh B. Suthar, Marco Vitoria, Rachel Baggaley, Carla Makhlouf Obermeyer, Craig McClure, Yves Souteyrand, Jos Perriens, James G. Kahn, Rod Bennett, Caoimhe Smyth, Brian Williams, Julio Montaner and Gottfried Hirnschall

Acknowledgements and Editorial (Exploring the Role of “Treatment as Prevention”) open Access plus

Volume: 9   Issue: 6
Pp: 352-354
Marianne Harris and Julio S.G. Montaner

Effects of Tipranavir, Darunavir, and Ritonavir on Platelet Function, Coagulation, and Fibrinolysis in Healthy Volunteers open Access plus

Volume: 9   Issue: 4
Pp: 237-246
Jens J. Kort, Stella Aslanyan, Joseph Scherer, John P. Sabo, Veronika Kohlbrenner and Patrick Robinson

The Therapeutic Potential of Adenosine Triphosphate as an Immune Modulator in the Treatment of HIV/AIDS: A Combination Approach with HAART open Access plus

Volume: 9   Issue: 4
Pp: 209-222
Marc C.E. Wagner

Rates of Initial Virological Suppression and Subsequent Virological Failure After Initiating Highly Active Antiretroviral Therapy: The Impact of Aboriginal Ethnicity and Injection Drug Use open Access plus

Volume: 8   Issue: 8
Pp: 649-658
L. J. Martin, S. Houston, Y. Yasui, T. C. Wild and L. D. Saunders

SHIV Infection Protects Against Heterologous Pathogenic SHIV Challenge in Macaques: A Gold-Standard for HIV-1 Vaccine Development? open Access plus

Volume: 7   Issue: 5
Pp: 497-503
Robert Sealy, Xiaoyan Zhan, Timothy D. Lockey, Louis Martin, James Blanchard, Vicki Traina-Dorge and Julia L. Hurwitz

What Strategies to Boost Production of Affordable Fixed-Dose Anti-Retroviral Drug Combinations for Children in the Developing World? open Access plus

Volume: 5   Issue: 2
Pp: 155-187
Daniele Dionisio, Robert Gass, Peter McDermott, Vincenzo Racalbuto, Marina Madeo, Giuseppe Braghieri, Siobhan Crowley, Eloan Dos Santos Pinheiro, Peter Graaff, Ashwin Vasan, Achara Eksaengsri, Helene Moller, Arun Kumar Khanna, Krisana Kraisintu, Sandeep Juneja, Stavros Nicolaou, Aloka Sengupta, Francesco Esperti and Daniela Messeri