ONLINE MANUSCRIPT SUBMISSION:
An online submission and tracking service via Internet facilitates a speedy and cost-effective submission of manuscripts. The full manuscript has to be submitted online via ScholarOne Manuscripts at mc04.manuscriptcentral.com/cares / View Submission Instructions
Manuscripts must be submitted by one of the authors of the manuscript, and should not be submitted by anyone on their behalf. The principal/corresponding author will be required to submit a Copyright Letter along with the manuscript, on behalf of all the co-authors (if any). The author(s) will confirm that the manuscript (or any part of it) has not been published previously or is not under consideration for publication elsewhere. Furthermore, any illustration, structure or table that has been published elsewhere must be reported, and copyright permission for reproduction must be obtained.
For all online submissions, please provide soft copies of all the materials (main text in MS Word or Tex/LaTeX), figures /illustrations in TIFF, PDF or JPEG, and chemical structures drawn in ChemDraw (CDX)/ISISDraw (TGF) as separate files, while a PDF version of the entire manuscript must also be included, embedded with all the figures/illustrations/tables/chemical structures etc.
It is imperative that before submission, authors should carefully proofread the files for special characters, mathematical symbols, Greek letters, equations, tables, references and images, to ensure that they appear in proper format.
References, figures, tables, chemical structures etc. should be referred to in the text at the appropriate place where they have been first discussed. Figure legends/captions should also be provided.
A successful electronic submission of a manuscript will be followed by a system-generated acknowledgement to the principal/corresponding author. Any queries therein should be addressed to email@example.com
The editorial policies of Bentham Science Publishers on publication ethics, peer-review, plagiarism, copyrights/ licenses, errata/corrections, and article retraction/ withdrawal can be viewed at Editorial Policy
It is mandatory that a signed Copyright Letter also be submitted along with the manuscript by the author to whom correspondence is to be addressed, delineating the scope of the submitted article declaring the potential competing interests, acknowledging contributions from authors and funding agencies, and certifying that the paper is prepared according to the 'Instructions for Authors'. All inconsistencies in the text and in the reference section and any typographical errors must be carefully checked and corrected before the submission of the manuscript. The article should not contain any such material or information that may be unlawful, defamatory, fabricated, plagiarized, or which would, if published, in any way whatsoever, violate the terms and conditions as laid down in the copyright agreement.
The authors acknowledge that the publishers have the legal right to take appropriate action against the authors for any such violation of the terms and conditions as laid down in the copyright agreement. Download the Copyright Letter
The total number of words for a published comprehensive review article is from 8000 to 40000 words, and for mini-review articles from 3000 to 6000 words.
Systematic Reviews includes systematic updates in review protocols, methods, research, and results from all fields of health for any studies and updates on already published issues.
Case reports should describe new observations of findings or novel/unique outcomes relevant to the filed. The total number of words for a published case report is 1500 to 2000 words.
There is no restriction on the number of figures, tables or additional files e.g. video clips, animation and datasets, that can be included with each article online. Authors should include all relevant supporting data with each article (Refer to Supplementary Material section).
Research articles should be 4000-8000 words excluding figures, structures, photographs, schemes, tables etc. There is a quota of 20% of published Research articles per issue in this journal.
Letters should be 3000-6000 words excluding figures, structures, photographs, schemes, tables etc. There is a quota of 20% of published Letter articles per issue in this journal.
Randomized Drug Clinical Trial Studies:
Trial studies should be 1500 to 40000 words excluding figures, structures, photographs, schemes, tables etc.
There is no restriction on the number of figures, tables or additional files e.g. video clips, animation and datasets, that can be included with each article online. Authors should include all relevant supporting data with each article (Refer to Supplementary Material section).
MANUSCRIPT SECTIONS FOR PAPERS:
Manuscripts submitted for research and review articles in the respective journal should be divided into the following sections:
- Title Page
- Structured Abstract
- Graphical Abstract
- Text Organization
- List of Abbreviations (if any)
- Consent for Publication
- Conflict of Interest
- Figures/Illustrations (if any)
- Chemical Structures (if any)
- Tables (if any)
- Supportive/Supplementary Material (if any)
The title of the article should be precise and brief and must not be more than 120 characters. Authors should avoid the use of non-standard abbreviations. The title must be written in title case except for articles, conjunctions and prepositions.
Authors should also provide a short ‘running title’. Title, running title, byline, correspondent footnote and keywords should be written as presented in original manuscripts.
Title page should include paper title, author(s) full name and affiliation, corresponding author(s) names complete affiliation/address, along with phone, fax and email.
The abstract of an article should be its clear, concise and accurate summary, having no more than 250 words, and including the explicit sub-headings (as in-line or run-in headings in bold). Use of abbreviations should be avoided and the references should not be cited in the abstract. Ideally, each abstract should include the following sub-headings, but these may vary according to requirements of the article.
A graphic should be included when possible with each manuscript for use in the Table of Contents (TOC). This must be submitted separately as an electronic file (preferred file types are EPS, PDF, TIFF, Microsoft Word, PowerPoint and CDX etc.). A graphical abstract, not exceeding 30 words along with the illustration, helps to summarize the contents of the manuscript in a concise pictorial form. It is meant as an aid for the rapid viewing of the journals' contents and to help capture the readers’ attention. The graphical abstract may feature a key structure, reaction, equation, etc. that the manuscript elucidates upon. It will be listed along with the manuscript title, authors’ names and affiliations in the contents page, typeset within an area of 5 cm by 17 cm, but it will not appear in the article PDF file or in print.
Graphical Abstracts should be submitted as a separate file (must clearly mention graphical abstract within the file) online via Bentham's Content Management System by selecting the option “supplementary material”.
6 to 8 keywords must be provided.
The main text should begin on a separate page and should be divided into title page, abstract and the main text. The text may be subdivided further according to the areas to be discussed, which should be followed by the List of Abbreviations, Conflict of Interest, Acknowledgements and Reference sections. For review, the manuscript should be divided into title page, abstract and the main text. The text may be subdivided further according to the areas to be discussed, which should be followed by the Acknowledgements and Reference sections. For Research Articles the manuscript should begin with the title page and abstract followed by the main text, which must be structured into separate sections as Introduction, Material and Methods, Results, Discussion, Conclusion, Conflict of Interest, Acknowledgements and References. The Review Article should mention any previous important recent and old reviews in the field and contain a comprehensive discussion starting with the general background of the field. It should then go on to discuss the salient features of recent developments. The authors should avoid presenting material which has already been published in a previous review. The authors are advised to present and discuss their observations in brief. The manuscript style must be uniform throughout the text and 10 pt Times New Roman fonts should be used. The full term for an abbreviation should precede its first appearance in the text unless it is a standard unit of measurement. The reference numbers should be given in square brackets in the text. Italics should be used for Binomial names of organisms (Genus and Species), for emphasis and for unfamiliar words or phrases. Non-assimilated words from Latin or other languages should also be italicized e.g. per se, et al. etc
Section headings should be numbered sequentially, left aligned and have the first letter capitalized, starting with the introduction. Sub-section headings however, should be in lower-case and italicized with their initials capitalized. They should be numbered as 1.1, 1.2, etc.
The Introduction section should include the background and aims of the research in a comprehensive manner.
MATERIALS AND METHODS:
This section provides details of the methodology used along with information on any previous efforts with corresponding references. Any details for further modifications and research should be included.
Repeated information should not be reported in the text of an article. A calculation section must include experimental data, facts and practical development from a theoretical perspective.
Results should be precise.
This should explore the significance of the results of the work, and present reproducible procedure. Extensive citations and discussion of published literature should be avoided.
The Results and discussions may be presented individually or combined in a single section with short and informative headings.
A small paragraph summarizing the contents of the article, presenting the final outcome of the research or proposing further study on the subject, may be given at the end of the article under the Conclusion section.
Ethical Approval of Studies and Informed Consent:
For human or animal experimental investigations, it is a prerequisite to provide a formal review and approval, or review and waiver, by an appropriate institutional review board or ethics committee and should be documented in your paper. For investigations undertaken on human subjects, state in the Methods section the manner in which the informed consent was obtained from the study participants (i.e., oral or written), where there is an unavoidable risk of breach of privacy- e.g., in a clinical photograph or in case details- the patient’s written consent or that of the next of kin, to publication must be obtained. We will ask you to send a signed consent form before publication. Consent must be obtained for all Case Reports and Clinical Pictures.’
Standard Protocol on Approvals, Registrations, Patient Consents & Animal Protection:
All clinical investigations must be conducted according to the Declaration of Helsinki principles. Authors must comply with the guidelines of the International Committee of Medical Journal Editors ( www.icmje.org) with regard to the patient's consent for research or participation in a study.
Patients' names, initials, or hospital numbers must not be mentioned anywhere in the manuscript (including figures). Editors may request that authors provide documentation of the formal review and recommendation from the institutional review board or ethics committee responsible for oversight of the study.
In addition to the standard patient consent for participation in research, authors are responsible for obtaining patient consent-to-disclose forms for all recognizable patients in photographs, videos, or other information that may be published in the Journal, in derivative works, or on the journal's web site and for providing the manuscript to the recognizable patient for review before submission. The consent-to-disclose form should indicate specific use (publication in the medical literature in print and online, with the understanding that patients and the public will have access) of the patient's information and any images in figures or videos, and must contain the patient's signature or that of a legal guardian along with a statement that the patient or legal guardian has been offered the opportunity to review the identifying materials and the accompanying manuscript.
For research involving animals, the authors should indicate whether the procedures followed were in accordance with the standards set forth in the eighth edition of Guide for the Care and Use of Laboratory Animals (https://www.grants.nih.gov/grants/olaw/guide-for-the-care-and-use-of-laboratory-animals_prepub.pdf; published by the National Academy of Sciences, The National Academies Press, Washington, D.C.).
Research Involving Animals
Research work on animals should be carried out in accordance with the NC3Rs ARRIVE Guidelines. For In Vivo Experiments, visit https://www.nc3rs.org.uk/arrive-guidelines
Authors must clearly state the name of the approval committee, highlighting that legal and ethical approval was obtained prior to initiation of the research work carried out on animals, and that the experiments were performed in accordance with the relevant guidelines and regulations stated below.
Registration of Systematic Reviews:
Bentham Science Publishers supports retrospective registration of systematic reviews, in a suitable registry (such as PROSPERO). The registered systematic review must include the registration number as the last line of the manuscript abstract.
Consent for Publication:
If the manuscript has an individuals’ data, such as personal detail, audio-video material etc., consent should be obtained from that individual. In case of children, consent should be obtained from the parent or the legal guardian.
A specific declaration of such approval and consent-to-disclose form must be made in the copyright letter and in a stand-alone paragraph at the end of the Methods section especially in the case of human studies where inclusion of a statement regarding obtaining the written informed consent from each subject or subject's guardian is a must. The original should be retained by the guarantor or corresponding author. Editors may request to provide the original forms by fax or email.
All such case reports should be followed by a proper consent prior to publishing.
Randomized Drug Clinical Trial Studies:
Randomized drug clinical trial studies are biomedical or health-related interventional and/or observational research studies conducted in phases in human beings who are randomly allocated to receive or not receive a preventive, therapeutic, or diagnostic intervention that follows a pre-defined protocol. The study is intended to determine the safety and efficacy of approaches to disease prevention, diagnosis and treatment.
Authors of randomized controlled trials are encouraged to submit trial protocols along with their manuscripts. All clinical trials must be registered (before recruitment of the first participant) at an appropriate online public trial registry that must be independent of for-profit interest (e.g.,www.clinicaltrials.gov). If you wish the editor(s) to consider an unregistered trial, please explain briefly why the trial has not been registered.
- All randomized clinical trials should include a flow diagram and authors should provide a completed randomized trial checklist (see CONSORT Flow Diagram and Checklist; www.consort-statement.org) and a trial protocol.
- Studies of diagnostic accuracy must be reported according to STARD guidelines; (www.stard-statement.org)
- Observational studies (cohort, case-control, or cross-sectional designs) must be reported according to the STROBE statement, and should be submitted with their protocols; (www.strobe-statement.org).
- Genetic association studies must be reported according to STREGA guidelines; (www.medicine.uottawa.ca)
- Systematic reviews and meta-analyses must be reported according to PRISMA guidelines; (www.prisma-statement.org)
- To find the reporting guidelines see (https://www.equator-network.org)
Important points to remember while submitting clinical trials:
- Each manuscript should clearly state an objective or hypothesis; the design and methods (including the study setting and dates, patients or participants with inclusion and exclusion criteria, or data sources, and how these were selected for the study); the essential features of any interventions; the main outcome measures; the main results of the study; a comment section placing the results in context with the published literature and addressing study limitations; and the conclusions. Data included in research reports must be original.
- Trial registry name, registration identification number, and the URL for the registry should be included at the end of the abstract and also in the space provided on the online manuscript submission form. If your research article reports the results of a controlled health care intervention, list the trial registry, along with the unique identifying number (Please note that there should be no space between the letters and numbers of your trial registration number). Studies designed for other purposes, such as to study pharmacokinetics or major toxicity (e.g., phase 1 trials), are exempted.
- All reports of randomized trials should include a section entitled “Randomization and Masking”, within the Methods section.
- The manuscript must include a statement identifying the institutional and/or licensing committee that has approved the experiments, including any relevant details.
- The SI system of units and the recommended international non-proprietary name (rINN) for drug names must be used. Kindly ensure that the dose, route, and frequency of administration of any drug you mention are correct.
- Please ensure that the clinical trials sponsored by pharmaceutical companies follow the guidelines on good publication practice: (www.gpp-guidelines.org)
The editors reserve the right to reject manuscripts that do not comply with the above-mentioned requirements. The author will be held responsible for false statements or failure to fulfill the above-mentioned requirements.
Greek Symbols and Special Characters:
Greek symbols and special characters often undergo formatting changes and get corrupted or lost during preparation of manuscript for publication. To ensure that all special characters used are embedded in the text, these special characters should be inserted as a symbol but should not be a result of any format styling (Symbol font face) otherwise they will be lost during conversion to PDF/XML.
Authors are encouraged to consult reporting guidelines. These guidelines provide a set of recommendations comprising a list of items relevant to their specific research design. Chemical equations, chemical names, mathematical usage, unit of measurements, chemical and physical quantity & units must conform to SI and Chemical Abstracts or IUPAC.
All kinds of measurements should be reported only in International System of Units (SI).
List of Abbreviations:
If abbreviations are used in the text either they should be defined in the text where first used, or a list of abbreviations can be provided.
Conflict of Interest:
Financial contributions and any potential conflict of interest must be clearly acknowledged under the heading ‘Conflict of Interest’. Authors must list the source(s) of funding for the study. This should be done for each author.
All individuals listed as authors must have contributed substantially to the design, performance, analysis, or reporting of the work and are required to indicate their specific contribution. Anyone (individual/company/institution) who has substantially contributed to the study for important intellectual content, or who was involved in the article’s drafting the manuscript or revising must also be acknowledged.
Guest or honorary authorship based solely on position (e.g. research supervisor, departmental head) is discouraged.
The specific requirements for authorship have been defined by the International Committee of Medical Journal Editors (www.icmje.org). Examples of authors' contributions are: 'designed research/study', 'performed research/study', 'contributed important reagents', 'collected data', 'analyzed data', 'wrote paper' etc. This information must be included in the submitted manuscript as a separate paragraph under the heading ‘Acknowledgements’. The corresponding author is responsible for obtaining permission from all co-authors for the submission of any version of the manuscript and for any changes in the authorship.
References must be listed in the numerical system (Vancouver). All references should be numbered sequentially [in square brackets] in the text and listed in the same numerical order in the reference section. The reference numbers must be finalized and the bibliography must be fully formatted before submission. It is necessary to list all authors if the total number of authors is 6 or less and for more than 6 authors use 6 authors and then et al. (the term “et al.” should be in italics).
See below few examples of references listed in the correct Vancouver style:
Typical Paper Reference:
Becker RE, Greig NH. Was Phenserine a Failure or Were Investigators Mislead by Methods? Curr Alzheimer Res 9: 1174-81 (2012).
Mortimer JA. The Nun Study: Risk Factors for Pathology and Clinical-Pathologic Correlations. Curr Alzheimer Res 9: 623-9 (2012).
Delacourte A, David JP, Sergeant N, Buee L, Wattez A, Vermersch P, et al. The biochemical pathway of neurofibrillary degeneration in aging and Alzheimer's disease. Neurology 52(6): 1158-1165 (1999).
Typical Chapter Reference:
Lahiri DK, Ge Y, Nurnberger JI, Yang EY, Walsh TJ and Bondy SC. Melatonin, nitric oxide synthase and oxidative stress. In (Eds: Nagatsu T, Nabeshima T, McCarty R and D Goldstein, D). Catecholamine Research: From Molecular Insights to Clinical Medicine. New York: Kluwer Academic/ Plenum Publishers pp. 245-248 (2002).
Stevenson WG, Friedman PL. In: Clinical trials in cardiovascular disease. (Ed: Hennekens CH). Philadelphia’: WB Saunders Co. pp 217-230 (1999).
Brown AM, Stubbs DW, Eds. Medical physiology. New York: Wiley (1983).
Harris AH, Eds. Economics and health: 1997: Proceedings of the 19th Australian Conference of Health Economists; 1997 Sep 13-14; Sydney, Australia. Kensington, N.S.W.: School of Health Services Management, University of New South Wales (1998).
Journal Article on the Internet:
Aylin P, Bottle A, Jarman B, Elliott, P. Paediatric cardiac surgical mortality in England after Bristol: descriptive analysis of hospital episode statistics 1991-2002. BMJ [serial on the Internet]. 2004 Oct 9; [cited 2004 October 15]; 329: [about 10 screens]. Available from: bmj.bmjjournals.com/cgi/content/full/329/7470/825
Kimura K, Lipeles A. Fuzzy controller component. US. Patent 14,860,040, 1996.
Borkowski MM. Infant sleep and feeling: a telephone survey of Hispanic Americans. PhD dissertation. Mount Pleasant (MI): Central Micihigan University 2002.
Citations for articles/material published exclusively online or in open access (free-to-view) , must contain the exact Web addresses (URLs) at the end of the reference(s), except those posted on an author’s Web site unless editorially essential, e.g. ‘Reference: Available from: URL’.
Some important points to remember:
- All references must be complete and accurate.
- Date of access should be provided for online citations.
- Journal names should be abbreviated according to the Index Medicus/MEDLINE.
- Punctuation should be properly applied as mentioned in the examples given above.
- Superscript in the in-text citations and reference section should be avoided.
- Abstracts, unpublished data and personal communications (which can only be included if prior permission has been obtained) should not be given in the references section. The details may however appear in the footnotes.
- The authors are encouraged to use a recent version of EndNote (version 5 and above) or Reference Manager (version 10) when formatting their reference list, as this allows references to be automatically extracted.
In case there is a need to present lengthy, but essential methodological details, appendices must be used, which can be a part of the article. An appendix must not exceed three pages (Times New Roman, 10 point fonts, 900 max. words per page).The information should be provided in a condensed form, ruling out the need of full sentences. A single appendix should be titled APPENDIX, while more than one can be titled APPENDIX A, APPENDIX B, and so on.
All authors must strictly follow the guidelines below for preparing illustrations for publication in Current Alzheimer Research. If the figures are found to be sub-standard, then the manuscripts will be rejected and the authors offered the option of figure improvement professionally by Eureka Science. The costs for such improvement will be charged to the authors.
Illustrations should be embedded in the text file, and must be numbered consecutively in the order of their appearance. Each figure should include only a single illustration which should be cropped to minimize the amount of space occupied by the illustration.
If a figure is in separate parts, all parts of the figure must be provided in a single composite illustration file.
Photographs should be provided with a scale bar if appropriate, as well as high-resolution component files.
Line Art image type is normally an image based on lines and text. It does not contain tonal or shaded areas. The preferred file format should be TIFF or EPS, with the color mode being Monochrome 1-bit or RGB, in a resolution of 900-1200 dpi.
Halftone image type is a continuous tone photograph containing no text. It should have the preferred file format TIFF, with color mode being RGB or Grayscale, in a resolution of 300 dpi.
Combination image type is an image containing halftone , text or line art elements. It should have the preferred file format TIFF, with color mode being RGB or Grayscale, in a resolution of 500-900 dpi.
Illustrations may be submitted in the following file formats:
EPS (preferred format for diagrams)
PDF (also especially suitable for diagrams)
PNG (preferred format for photos or images)
Microsoft Word (version 5 and above; figures must be a single page)
PowerPoint (figures must be a single page)
JPEG (conversion should be done using the original file)
Bentham Science does not process figures submitted in GIF format.
For TIFF or EPS figures with considerably large file size restricting the file size in online submissions is advisable. Authors may therefore convert to JPEG format before submission as this results in significantly reduced file size and upload time, while retaining acceptable quality. JPEG is a ‘lossy’ format. However, in order to maintain acceptable image quality, it is recommended that JPEG files are saved at High or Maximum quality.
Zipit or Stuffit tools should not be used to compress files prior to submission as the resulting compression through these tools is always negligible.
Please refrain from supplying:
- Graphics embedded in word processor (spreadsheet, presentation) document.
- Optimized files optimized for screen use (like GIF, BMP, PICT, WPG) because of the low resolution.
- Files with too low a resolution.
- Graphics that are disproportionately large for the content.
Image Conversion Tools:
There are many software packages, many of them freeware or shareware, capable of converting to and from different graphics formats, including PNG.
General tools for image conversion include Graphic Converter on the Macintosh, Paint Shop Pro, for Windows, and ImageMagick, available on Macintosh, Windows and UNIX platforms.
Bitmap images (e.g. screenshots) should not be converted to EPS as they result in a much larger file size than the equivalent JPEG, TIFF, PNG or BMP, and poor quality. EPS should only be used for images produced by vector-drawing applications such as Adobe Illustrator or CorelDraw. Most vector-drawing applications can be saved in, or exported as, EPS format. If the images were originally prepared in an Office application, such as Word or PowerPoint, original Office files should be directly uploaded to the site, instead of being converted to JPEG or another format of low quality.
- The cost for each individual page of color figures/plates/illustrations is US$ 997.
- Color figures should be supplied in CMYK and not in RGB colors.
Note for authors: To maintain publication quality, figures submitted in colour will be published in colour only.
Chemical structures MUST be prepared in ChemDraw/CDX and provided as separate file.
Structure Drawing Preferences:
[As according to the ACS style sheet]
||18% of width
||14.4 pt (0.500cm, 0.2in)
||2.0 pt (0.071cm, 0.0278in)
||0.6 pt (0.021cm, 0.0084in)
||1.6 pt (0.096cm)
||2.5 pt (0.088cm, 0.0347in)
||Times New Roman
|Under the Preference Choose:
|Under Page Setup Use:
- Data Tables should be submitted in Microsoft Word table format.
- Each table should include a title/caption being explanatory in itself with respect to the details discussed in the table. Detailed legends may then follow.
- Table number in bold font i.e. Table 1, should follow a title. The title should be in small case with the first letter in caps. A full stop should be placed at the end of the title.
- Tables should be embedded in the text exactly according to their appropriate placement in the submitted manuscript.
- Columns and rows of data should be made visibly distinct by ensuring that the borders of each cell are displayed as black lines.
- Tables should be numbered in Arabic numerals sequentially in order of their citation in the body of the text.
- If a reference is cited in both the table and text, please insert a lettered footnote in the table to refer to the numbered reference in the text.
- Tabular data provided as additional files can be submitted as an Excel spreadsheet.
Supportive/Supplementary Material (if any):
We do encourage to append supportive material, for example a PowerPoint file containing a talk about the study, a PowerPoint file containing additional screenshots, a Word, RTF, or PDF document showing the original instrument(s) used, a video, or the original data (SAS/SPSS files, Excel files, Access Db files etc.) provided it is inevitable or endorsed by the journal's Editor.
Supportive/Supplementary material intended for publication must be numbered and referred to in the manuscript but should not be a part of the submitted paper. In-text citations as well as a section with the heading "Supportive/Supplementary Material" before the "References" section should be provided. Here, list all Supportive/Supplementary Material and include a brief caption line for each file describing its contents.
Any additional files will be linked to the final published article in the form supplied by the author, but will not be displayed within the paper. They will be made available in exactly the same form as originally provided only on our Web site. Please also make sure that each additional file is a single table, figure or movie (please do not upload linked worksheets or PDF files larger than one sheet). Supportive/ Supplementary material must be provided in a single zipped file not larger than 4 MB.
Authors must clearly indicate if these files are not for publication but meant for the reviewers'/editors' perusal only.