Current Alzheimer Research

Editor-in-Chief:

Debomoy K. Lahiri  
Department of Psychiatry, Indiana University School of Medicine
Neuroscience Research Center
Indianapolis, IN 46202
USA

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Editor's Choice

(-)-Phenserine and Inhibiting Pre-Programmed Cell Death: In Pursuit of a Novel Intervention for Alzheimer’s Disease open access plus

Volume: 15   Issue: 9
Pp: 883-891
Robert E. Becker*, Nigel H. Greig, Debomoy K. Lahiri, Joseph Bledsoe, Sarah Majercik, Clive Ballard, Dag Aarsland, Lon S. Schneider, Douglas Flanagan, Ramprakash Govindarajan, Mary Sano, Luigi Ferrucci and Dimitrios Kapogiannis
DOI: 10.2174/1567205015666180110120026

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Memorization Test and Resting State EEG Components in Mild and Subjective Cognitive Impairment

Volume: 15   Issue: 9
Pp: 809-819
Giulia Mazzon*, Federica De Dea, Tatiana Cattaruzza, Paolo Manganotti, Fabrizio Monti and Agostino Accardo
DOI: 10.2174/1567205015666180427114520

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Semantic Intrusions and Failure to Recover From Semantic Interference in Mild Cognitive Impairment: Relationship to Amyloid and Cortical Thickness open access plus

Volume: 15   Issue: 9
Pp: 848-855
Rosie E. Curiel, David A. Loewenstein*, Monica Rosselli, Ailyn Penate, Maria T. Greig-Custo, Russell M. Bauer, Salvador M. Guinjoan, Kevin S. Hanson, Chunfei Li, Gabriel Lizarraga, William W. Barker, Valeria Torres, Steven DeKosky, Malek Adjouadi and Ranjan Duara
DOI: 10.2174/1567205015666180427122746

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Treponema, Iron and Neurodegeneration

Volume: 15   Issue: 8
Pp: 716-722
A. Jolivet-Gougeon* and M. Bonnaure-Mallet
DOI: 10.2174/1567205013666161122093404

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Estimating Alzheimer’s Disease Progression Rates from Normal Cognition Through Mild Cognitive Impairment and Stages of Dementia

Volume: 15   Issue: 8
Pp: 777-788
Matthew Davis, Thomas O`Connell, Scott Johnson, Stephanie Cline*, Elizabeth Merikle, Ferenc Martenyi and Kit Simpson
DOI: 10.2174/1567205015666180119092427

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Tolfenamic Acid Prevents Amyloid β-induced Olfactory Bulb Dysfunction In Vivo

Volume: 15   Issue: 8
Pp: 731-742
José M. Cornejo-Montes-de-Oca, Rebeca Hernández-Soto, Arturo G. Isla, Carlos E. Morado-Urbina and Fernando Peña-Ortega*
DOI: 10.2174/1567205015666180223091233

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Tolfenamic Acid: A Modifier of the Tau Protein and its Role in Cognition and Tauopathy

Volume: 15   Issue: 7
Pp: 655-663
Joanna K. Chang, Allison Leso, Gehad M. Subaiea, Asma Lahouel, Anwar Masoud, Foqia Mushtaq, Reem Deeb, Aseel Eid, Miriam Dash , Syed W. Bihaqi and Nasser H. Zawia*
DOI: 10.2174/1567205015666180119104036

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Melatonin Treatment Enhances Aβ Lymphatic Clearance in a Transgenic Mouse Model of Amyloidosis

Volume: 15   Issue: 7
Pp: 637-642
M.A. Pappolla*, E. Matsubara, R. Vidal, J. Pacheco-Quinto, B. Poeggeler, M. Zagorski and K. Sambamurti
DOI: 10.2174/1567205015666180411092551

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Up-regulation of DMN Connectivity in Mild Cognitive Impairment Via Network-based Cognitive Training open access plus

Volume: 15   Issue: 6
Pp: 578-589
Matteo De Marco, Francesca Meneghello, Cristina Pilosio, Jessica Rigon and Annalena Venneri*
DOI: 10.2174/1567205015666171212103323

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Is it All Said for NSAIDs in Alzheimer’s Disease? Role of Mitochondrial Calcium Uptake

Volume: 15   Issue: 6
Pp: 504-510
Sara Sanz-Blasco, Maria Calvo-Rodríguez, Erica Caballero, Monica Garcia-Durillo, Lucia Nunez and Carlos Villalobos*
DOI: 10.2174/1567205015666171227154016

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Vitamin D Increases Aβ140 Plasma Levels and Protects Lymphocytes from Oxidative Death in Mild Cognitive Impairment Patients

Volume: 15   Issue: 6
Pp: 561-569
Carol D. SanMartín, Mauricio Henriquez, Carlos Chacon, Daniela P. Ponce, Felipe Salech, Nicole K. Rogers and Maria I. Behrens*
DOI: 10.2174/1567205015666171227154636

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Quality of Life in Dementia Sufferers: The Role of Diet and Exercise

Volume: 15   Issue: 5
Pp: 400-407
Pasquale Ricci, Francesco Massoni*, Lidia Ricci, Emanuela Onofri, Giuseppe Donato and Serafino Ricci
DOI: 10.2174/1567205014666170925151614

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A Biomarker Combining Imaging and Neuropsychological Assessment for Tracking Early Alzheimer's Disease in Clinical Trials

Volume: 15   Issue: 5
Pp: 429-442
Nishant Verma, S. Natasha Beretvas, Belen Pascual, Joseph C. Masdeu, Mia K. Markey* and The Alzheimer's Disease Neuroimaging Initiative
DOI: 10.2174/1567205014666171106150309

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The Correlations between Postmortem Brain Pathologies and Cognitive Dysfunction in Aging and Alzheimer's Disease

Volume: 15   Issue: 5
Pp: 462-473
Wen-Ying Qiu, Qian Yang, Wanying Zhang, Naili Wang, Di Zhang, Yue Huang* and Chao Ma*
DOI: 10.2174/1567205014666171106150915

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Modulation of Inflammation as a Way of Delaying Alzheimer's Disease Progression: The Diet's Role

Volume: 15   Issue: 4
Pp: 363-380
R. Businaro*, M. Corsi, R. Asprino, C. Di Lorenzo, D. Laskin, R.M. Corbo, S. Ricci and A. Pinto
DOI: 10.2174/1567205014666170829100100

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Pharmacogenetics of Angiotensin-Converting Enzyme Inhibitors in Patients with Alzheimer's Disease Dementia

Volume: 15   Issue: 4
Pp: 386-398
Fabricio Ferreira de Oliveira*, Elizabeth Suchi Chen, Marilia Cardoso Smith and Paulo Henrique Ferreira Bertolucci
DOI: 10.2174/1567205014666171016101816

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Erythrocyte Associated Amyloid-β as Potential Biomarker to Diagnose Dementia

Volume: 15   Issue: 4
Pp: 381-385
Michele Lauriola, Giulia Paroni*, Filomena Ciccone, Grazia D`Onofrio, Leandro Cascavilla, Francesco Paris, Carolina Gravina, Maria Urbano, Davide Seripa and Antonio Greco
DOI: 10.2174/1567205014666171110160556

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Ongoing Electroencephalographic Activity Associated with Cortical Arousal in Transgenic PDAPP Mice (hAPP V717F)

Volume: 15   Issue: 3
Pp: 259-272
Claudio Del Percio, Wilhelmus Drinkenburg, Susanna Lopez, Cristina Limatola, Jesper F. Bastlund, Ditte Z. Christensen, Jan T. Pedersen, Gianluigi Forloni, Angelisa Frasca, Francesco M. Noe, Marina Bentivoglio, Paolo F. Fabene, Giuseppe Bertini, Valeria Colavito, Sophie Dix, Raffaele Ferri, Regis Bordet, Jill C. Richardson and Claudio Babiloni*
DOI: 10.2174/1567205014666170704113405

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Map Learning in Normal Aging: The Role of Individual Visuo-Spatial Abilities and Implications

Volume: 15   Issue: 3
Pp: 205-218
Chiara Meneghetti*, Veronica Muffato, Erika Borella and Rossana De Beni
DOI: 10.2174/1567205014666171030113515

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CDK5 and MAPT Gene Expression in Alzheimer's Disease Brain Samples

Volume: 15   Issue: 2
Pp: 182-186
Josianne T. Fukasawa, Roger W. de Labio, Lucas T. Rasmussen, Lucieni C. de Oliveira, Elizabeth Chen, Joao Villares, Gustavo Tureck, Marilia de Arruda C. Smith and Spencer L.M. Payao*
DOI: 10.2174/1567205014666170713160407

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Use of Speech Analyses within a Mobile Application for the Assessment of Cognitive Impairment in Elderly People

Volume: 15   Issue: 2
Pp: 120-129
Alexandra Konig*, Aharon Satt, Alex Sorin, Ran Hoory, Alexandre Derreumaux, Renaud David and Phillippe H. Robert
DOI: 10.2174/1567205014666170829111942

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Body Mass Index (BMI) and Cognitive Functions in Later Life

Volume: 15   Issue: 2
Pp: 195-200
Yadollah A. Momtaz, Sharifah A. Haron, Tengku A. Hamid, Rahimah Ibrahim and Parisa T. Tanjani*
DOI: 10.2174/1567205014666171004114246

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Alzheimer's Disease and NQO1: Is there a Link? promotion: free to download

Volume: 15   Issue: 1
Pp: 56-66
Jamuna Chhetri*, Anna E. King and Nuri Gueven
DOI: 10.2174/1567205014666170203095802

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Ginkgo biloba Extract EGb761 Attenuates Hyperhomocysteinemia-induced AD Like Tau Hyperphosphorylation and Cognitive Impairment in Rats promotion: free to download

Volume: 15   Issue: 1
Pp: 89-99
Kuan Zeng, Mengzhu Li, Jichang Hu, Yacoubou Abdoul Razak Mahaman, Jian Bao, Fang Huang, Yiyuan Xia, Xinghua Liu, Qun Wang, Jian-Zhi Wang, Yang Yang, Rong Liu and Xiaochuan Wang*
DOI: 10.2174/1567205014666170829102135

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The Clock Drawing Test: A Reasonable Instrument to Assess Probable Dementia in Primary Care? promotion: free to download

Volume: 15   Issue: 1
Pp: 38-43
Katinka Reiner, Tilly Eichler, Johannes Hertel, Wolfgang Hoffmann and Jochen Rene Thyrian*
DOI: 10.2174/1567205014666170908101822

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Antioxidant SkQ1 Alleviates Signs of Alzheimer’s Disease-like Pathology in Old OXYS Rats by Reversing Mitochondrial Deterioration

Volume: 14   Issue: 12
Pp: 1283-1292
Nataliya G. Kolosova*, Mikhail A. Tyumentsev, Natalia A. Muraleva, Elena Kiseleva, Anton O. Vitovtov and Natalia A. Stefanova*
DOI: 10.2174/1567205014666170621111033

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Patients with Increased Non-Ceruloplasmin Copper Appear a Distinct Sub-Group of Alzheimer's Disease: A Neuroimaging Study

Volume: 14   Issue: 12
Pp: 1318-1326
Rosanna Squitti*, Ilaria Simonelli, Emanuele Cassetta, Domenico Lupoi, Mauro Rongioletti, Mariacarla Ventriglia and Mariacristina Siotto
DOI: 10.2174/1567205014666170623125156

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Neuroinflammation and Alzheimer's Disease: Implications for Microglial Activation

Volume: 14   Issue: 11
Pp: 1140-1148
Francesca Regen, Julian Hellmann-Regen, Erica Costantini and Marcella Reale*
DOI: 10.2174/1567205014666170203141717

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Peripheral Blood Mononuclear Cells of Alzheimer's Disease Patients Control CCL4 and CXCL10 Levels in a Human Blood Brain Barrier Model

Volume: 14   Issue: 11
Pp: 1215-1228
Julie Verite*, Thierry Janet, Adrien Julian, Damien Chassaing, Guylene Page and Marc Paccalin
DOI: 10.2174/1567205014666170417110337

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Applying Melanopic Lux to Measure Biological Light Effects on Melatonin Suppression and Subjective Sleepiness

Volume: 14   Issue: 10
Pp: 1042-1052
Claudia Nowozin , Amely Wahnschaffe, Andrea Rodenbeck , Jan de Zeeuw, Sven Hädel , Ruslan Kozakov , Heinz Schöpp, Mirjam Münch* and Dieter Kunz*
DOI: 10.2174/1567205014666170523094526

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Implementation of Dynamic Lighting in a Nursing Home: Impact on Agitation but not on Rest-Activity Patterns

Volume: 14   Issue: 10
Pp: 1076-1083
Amely Wahnschaffe*, Claudia Nowozin, Sven Haedel, Andreas Rath, Stefan Appelhof, Mirjam Münch and Dieter Kunz
DOI: 10.2174/1567205014666170608092411

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Modulation of Retinal Arteriolar Central Reflection by APOE Genotype

Volume: 14   Issue: 9
Pp: 916-923
Shaun Frost*, Alauddin Bhuiyan, David Offerman, James D. Doecke, S. Lance Macaulay, Hamid R. Sohrabi, David Ames, Colin Masters, Ralph N. Martins, Yogesan Kanagasingam and AIBL Research Group
DOI: 10.2174/1567205014666170309115016

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Protective Effect of Aspirin Against Oligomeric Aβ42 Induced Mitochondrial Alterations and Neurotoxicity in Differentiated EC P19 Neuronal Cells

Volume: 14   Issue: 8
Pp: 810-819
Hamendra Singh Parmar*, Zbynek Houdek, Martin Pesta, Cerna Vaclava, Pavel Dvorak and Jiri Hatina
DOI: 10.2174/1567205014666170203104757

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Molecular Targets of Tannic Acid in Alzheimer's Disease

Volume: 14   Issue: 8
Pp: 861-869
Nady Braidy*, Bat-Erdene Jugder, Anne Poljak, Tharusha Jayasena, Seyed Mohammad Nabavi, Perminder Sachdev and Ross Grant*
DOI: 10.2174/1567205014666170206163158

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Abnormal Clock Gene Expression and Locomotor Activity Rhythms in Two Month-Old Female APPSwe/PS1dE9 Mice open access plus

Volume: 14   Issue: 8
Pp: 850-860
Olaide Oyegbami, Hilary M. Collins, Marie-Christine Pardon, Francis J.P. Ebling, David M. Heery and Paula M. Moran*
DOI: 10.2174/1567205014666170317113159

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Long-Term Extensions of Randomized Vaccination Trials of ACC-001 and QS-21 in Mild to Moderate Alzheimer’s Disease open access plus

Volume: 14   Issue: 7
Pp: 696-708
Michael Hull*, Carl Sadowsky, Heii Arai, Ghislaine Le Prince Leterme, Ann Holstein, Kevin Booth, Yahong Peng, Tamotsu Yoshiyama, Hideo Suzuki, Nzeera Ketter, Enchi Liu and J. Michael Ryan
DOI: 10.2174/1567205014666170117101537

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Clinical and Environmental Correlates of Serum BDNF: A Descriptive Study with Plausible Implications for AD Research

Volume: 14   Issue: 7
Pp: 722-730
Galit Weinstein*, Sarah R. Preis, Alexa S. Beiser, Bernhard Kaess, Tai C. Chen, Claudia Satizabal, Faisal Rahman, Emelia J. Benjamin, Ramachandran S. Vasan and Sudha Seshadri
DOI: 10.2174/1567205014666170203094520

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Change in INSR, APBA2 and IDE Gene Expressions in Brains of Alzheimer's Disease Patients

Volume: 14   Issue: 7
Pp: 760-765
Isabela Bazzo da Costa, Roger Willian de Labio, Lucas Trevizani Rasmussen, Gustavo Arruda Viani, Elizabeth Chen, Joao Villares, Gustavo Turecki, Marilia de Arruda Cardoso Smith and Spencer L. M. Payao*
DOI: 10.2174/1567205014666170203100734

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Tauopathies – Focus on Changes at the Neurovascular Unit

Volume: 14   Issue: 7
Pp: 790-801
Alena Michalicova, William A. Banks, Jaroslav Legath and Andrej Kovac*
DOI: 10.2174/1567205014666170203143336

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GSK3β 5'-flanking DNA Methylation and Expression in Alzheimer’s Disease Patients

Volume: 14   Issue: 7
Pp: 753-759
Vincenzina Nicolia*, Viviana Ciraci, Rosaria A. Cavallaro, Isidre Ferrer, Sigfrido Scarpa and Andrea Fuso
DOI: 10.2174/1567205014666170203153325

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Omega-3 Fatty Acids: Repurposing Opportunities for Cognition and Biobehavioral Disturbances in MCI and Dementia

Volume: 14   Issue: 3
Pp: 240-254
Christian Knöchel, Martin Voss, Florian Gruter, Gilberto S. Alves, Silke Matura, Beate Sepanski, Michael Stablein, Dominik Kraft, David Prvulovic, Andre F. Carvalho, Andreas Reif and Viola Oertel-Knochel
DOI: 10.2174/1567205013666160602235520

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Uleine Disrupts Key Enzymatic and Non-Enzymatic Biomarkers that Leads to Alzheimer’s Disease

Volume: 14   Issue: 3
Pp: 317-326
Claudia Seidl, Cid Aimbire de Moraes Santos, Angela De Simone, Manuela Bartolini, Almeriane Maria Weffort-Santos and Vincenza Andrisano
DOI: 10.2174/1567205013666161026150455

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Effectiveness of a Standardized and Specific Follow-Up in Memory Centers in Patients with Alzheimer’s Disease

Volume: 14   Issue: 3
Pp: 255-267
Laure Rouch, Philippe Cestac, Charlene Cool, Catherine Helmer, Jean-Francois Dartigues, Claudine Berr, Olivier Rouaud, Bruno Vellas, Sandrine Andrieu and the REAL-FR Study Group and the 3C Study Group
DOI: 10.2174/1567205013666161108114850

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Potential for Stem Cells Therapy in Alzheimer’s Disease: Do Neurotrophic Factors Play Critical Role?

Volume: 14   Issue: 2
Pp: 208-220
Parul Bali, Debomoy K. Lahiri, Avijit Banik, Bimla Nehru and Akshay Anand
DOI: 10.2174/1567205013666160314145347

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Role of Artificial Intelligence Techniques (Automatic Classifiers) in Molecular Imaging Modalities in Neurodegenerative Diseases

Volume: 14   Issue: 2
Pp: 198-207
Silvia Cascianelli, Michele Scialpi, Serena Amici, Nevio Forini, Matteo Minestrini, Mario Luca Fravolini, Helmut Sinzinger, Orazio Schillaci and Barbara Palumbo
DOI: 10.2174/1567205013666160620122926

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Non-Ceruloplasmin Copper Distinguishes A Distinct Subtype of Alzheimer’s Disease: A Study of EEG-Derived Brain Activity

Volume: 13   Issue: 12
Pp: 1374-1384
Franca Tecchio, Fabrizio Vecchio, Mariacarla Ventriglia, Camillo Porcaro, Francesca Miraglia, Mariacristina Siotto, Paolo M. Rossini, Mauro Rongioletti and Rosanna Squitti
DOI: 10.2174/1567205013666160603001131

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MCI Patients in Europe: Medication and Comorbidities. The DESCRIPA Study

Volume: 13   Issue: 12
Pp: 1407-1413
Magda Tsolaki, Vasileios Papaliagkas, Giovanni Frisoni, Roy Jones, Jacques Touchon, Luiza Spiru, Bruno Vellas, Frans Verhey, Bengt Winblad, Pieter Jelle Visser and on behalf of the DESCRIPA Study Group
DOI: 10.2174/1567205013666160603002704

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The Association Between Alcohol Use and the Progression of Alzheimer’s Disease

Volume: 13   Issue: 12
Pp: 1356-1362
Devorah Heymann, Yaakov Stern, Stephanie Cosentino, Oksana Tatarina-Nulman, Jhedy N. Dorrejo and Yian Gu
DOI: 10.2174/1567205013666160603005035

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Drug Development of Small-Molecule Inhibitors of AD-Relevant Kinases as Novel Perspective Multitargeted Approach

Volume: 13   Issue: 12
Pp: 1330-1336
V. Tell, I. Hilbrich, M. Holzer, Frank Totzke, Christoph Schachtele, Inna Slynko, Wolfgang Sippl and A. Hilgeroth
DOI: 10.2174/1567205013666160615091821

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DNA Double Strand Breaks: A Common Theme in Neurodegenerative Diseases

Volume: 13   Issue: 11
Pp: 1208-1218
Daniela Merlo, Cristiana Mollinari, Mauro Racaniello, Enrico Garaci and Alessio Cardinale
DOI: 10.2174/1567205013666160401114915

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Alzheimer’s Disease Genetic Risk Factor APOE-ε4 Also Affects Normal Brain Function

Volume: 13   Issue: 11
Pp: 1200-1207
Amanda M. Di Battista, Nicolette M. Heinsinger and G. William Rebeck
DOI: 10.2174/1567205013666160401115127

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Ceramide and Sphingosine-1-Phosphate in Cell Death Pathways : Relevance to the Pathogenesis of Alzheimer's Disease

Volume: 13   Issue: 11
Pp: 1232-1248
Sankha Shubhra Chakrabarti, Aritri Bir, Jit Poddar, Maitrayee Sinha, Anirban Ganguly and Sasanka Chakrabarti
DOI: 10.2174/1567205013666160603004239

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Neuropsychiatric Disturbances in Mild Cognitive Impairment (MCI): A Systematic Review of Population-Based Studies

Volume: 13   Issue: 10
Pp: 1066-1082
Cristiano A. Köhler, Thaís F. Magalhaes, Joao M.M.P. Oliveira, Gilberto S. Alves, Christian Knochel, Viola Oertel-Knöchel, Johannes Pantel and André F. Carvalho
DOI: 10.2174/1567205013666160502123129

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Glial Cells – The Key Elements of Alzheimer´s Disease

Volume: 13   Issue: 8
Pp: 894-911
David Dzamba, Lenka Harantova, Olena Butenko and Miroslava Anderova
DOI: 10.2174/1567205013666160129095924

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Lithium, a Therapy for AD: Current Evidence from Clinical Trials of Neurodegenerative Disorders

Volume: 13   Issue: 8
Pp: 879-886
Orestes V. Forlenza, Ivan Aprahamian, Vanessa J. de Paula and Tomas Hajek
DOI: 10.2174/1567205013666160219112854

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