Current Alzheimer Research

Debomoy K. Lahiri  
Department of Psychiatry, Indiana University School of Medicine
Neuroscience Research Center
Indianapolis, IN 46202
USA

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Antioxidant SkQ1 Alleviates Signs of Alzheimer’s Disease-like Pathology in Old OXYS Rats by Reversing Mitochondrial Deterioration

Volume: 14   Issue: 12
Pp: 1283-1292
Nataliya G. Kolosova*, Mikhail A. Tyumentsev, Natalia A. Muraleva, Elena Kiseleva, Anton O. Vitovtov and Natalia A. Stefanova*
DOI: 10.2174/1567205014666170621111033

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Patients with Increased Non-Ceruloplasmin Copper Appear a Distinct Sub-Group of Alzheimer's Disease: A Neuroimaging Study

Volume: 14   Issue: 12
Pp: 1318-1326
Rosanna Squitti*, Ilaria Simonelli, Emanuele Cassetta, Domenico Lupoi, Mauro Rongioletti, Mariacarla Ventriglia and Mariacristina Siotto
DOI: 10.2174/1567205014666170623125156

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Neuroinflammation and Alzheimer's Disease: Implications for Microglial Activation

Volume: 14   Issue: 11
Pp: 1140-1148
Francesca Regen, Julian Hellmann-Regen, Erica Costantini and Marcella Reale*
DOI: 10.2174/1567205014666170203141717

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Peripheral Blood Mononuclear Cells of Alzheimer's Disease Patients Control CCL4 and CXCL10 Levels in a Human Blood Brain Barrier Model

Volume: 14   Issue: 11
Pp: 1215-1228
Julie Verite*, Thierry Janet, Adrien Julian, Damien Chassaing, Guylene Page and Marc Paccalin
DOI: 10.2174/1567205014666170417110337

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Applying Melanopic Lux to Measure Biological Light Effects on Melatonin Suppression and Subjective Sleepiness

Volume: 14   Issue: 10
Pp: 1042-1052
Claudia Nowozin , Amely Wahnschaffe, Andrea Rodenbeck , Jan de Zeeuw, Sven Hädel , Ruslan Kozakov , Heinz Schöpp, Mirjam Münch* and Dieter Kunz*
DOI: 10.2174/1567205014666170523094526

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Implementation of Dynamic Lighting in a Nursing Home: Impact on Agitation but not on Rest-Activity Patterns

Volume: 14   Issue: 10
Pp: 1076-1083
Amely Wahnschaffe*, Claudia Nowozin, Sven Haedel, Andreas Rath, Stefan Appelhof, Mirjam Münch and Dieter Kunz
DOI: 10.2174/1567205014666170608092411

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Modulation of Retinal Arteriolar Central Reflection by APOE Genotype

Volume: 14   Issue: 9
Pp: 916-923
Shaun Frost*, Alauddin Bhuiyan, David Offerman, James D. Doecke, S. Lance Macaulay, Hamid R. Sohrabi, David Ames, Colin Masters, Ralph N. Martins, Yogesan Kanagasingam and AIBL Research Group
DOI: 10.2174/1567205014666170309115016

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Protective Effect of Aspirin Against Oligomeric Aβ42 Induced Mitochondrial Alterations and Neurotoxicity in Differentiated EC P19 Neuronal Cells

Volume: 14   Issue: 8
Pp: 810-819
Hamendra Singh Parmar*, Zbynek Houdek, Martin Pesta, Cerna Vaclava, Pavel Dvorak and Jiri Hatina
DOI: 10.2174/1567205014666170203104757

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Molecular Targets of Tannic Acid in Alzheimer's Disease

Volume: 14   Issue: 8
Pp: 861-869
Nady Braidy*, Bat-Erdene Jugder, Anne Poljak, Tharusha Jayasena, Seyed Mohammad Nabavi, Perminder Sachdev and Ross Grant*
DOI: 10.2174/1567205014666170206163158

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Abnormal Clock Gene Expression and Locomotor Activity Rhythms in Two Month-Old Female APPSwe/PS1dE9 Mice open access plus

Volume: 14   Issue: 8
Pp: 850-860
Olaide Oyegbami, Hilary M. Collins, Marie-Christine Pardon, Francis J.P. Ebling, David M. Heery and Paula M. Moran*
DOI: 10.2174/1567205014666170317113159

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Long-Term Extensions of Randomized Vaccination Trials of ACC-001 and QS-21 in Mild to Moderate Alzheimer’s Disease open access plus

Volume: 14   Issue: 7
Pp: 696-708
Michael Hull*, Carl Sadowsky, Heii Arai, Ghislaine Le Prince Leterme, Ann Holstein, Kevin Booth, Yahong Peng, Tamotsu Yoshiyama, Hideo Suzuki, Nzeera Ketter, Enchi Liu and J. Michael Ryan
DOI: 10.2174/1567205014666170117101537

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Clinical and Environmental Correlates of Serum BDNF: A Descriptive Study with Plausible Implications for AD Research

Volume: 14   Issue: 7
Pp: 722-730
Galit Weinstein*, Sarah R. Preis, Alexa S. Beiser, Bernhard Kaess, Tai C. Chen, Claudia Satizabal, Faisal Rahman, Emelia J. Benjamin, Ramachandran S. Vasan and Sudha Seshadri
DOI: 10.2174/1567205014666170203094520

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Change in INSR, APBA2 and IDE Gene Expressions in Brains of Alzheimer's Disease Patients

Volume: 14   Issue: 7
Pp: 760-765
Isabela Bazzo da Costa, Roger Willian de Labio, Lucas Trevizani Rasmussen, Gustavo Arruda Viani, Elizabeth Chen, Joao Villares, Gustavo Turecki, Marilia de Arruda Cardoso Smith and Spencer L. M. Payao*
DOI: 10.2174/1567205014666170203100734

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Tauopathies – Focus on Changes at the Neurovascular Unit

Volume: 14   Issue: 7
Pp: 790-801
Alena Michalicova, William A. Banks, Jaroslav Legath and Andrej Kovac*
DOI: 10.2174/1567205014666170203143336

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GSK3β 5'-flanking DNA Methylation and Expression in Alzheimer’s Disease Patients

Volume: 14   Issue: 7
Pp: 753-759
Vincenzina Nicolia*, Viviana Ciraci, Rosaria A. Cavallaro, Isidre Ferrer, Sigfrido Scarpa and Andrea Fuso
DOI: 10.2174/1567205014666170203153325

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Omega-3 Fatty Acids: Repurposing Opportunities for Cognition and Biobehavioral Disturbances in MCI and Dementia

Volume: 14   Issue: 3
Pp: 240-254
Christian Knöchel, Martin Voss, Florian Gruter, Gilberto S. Alves, Silke Matura, Beate Sepanski, Michael Stablein, Dominik Kraft, David Prvulovic, Andre F. Carvalho, Andreas Reif and Viola Oertel-Knochel
DOI: 10.2174/1567205013666160602235520

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Uleine Disrupts Key Enzymatic and Non-Enzymatic Biomarkers that Leads to Alzheimer’s Disease

Volume: 14   Issue: 3
Pp: 317-326
Claudia Seidl, Cid Aimbire de Moraes Santos, Angela De Simone, Manuela Bartolini, Almeriane Maria Weffort-Santos and Vincenza Andrisano
DOI: 10.2174/1567205013666161026150455

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Effectiveness of a Standardized and Specific Follow-Up in Memory Centers in Patients with Alzheimer’s Disease

Volume: 14   Issue: 3
Pp: 255-267
Laure Rouch, Philippe Cestac, Charlene Cool, Catherine Helmer, Jean-Francois Dartigues, Claudine Berr, Olivier Rouaud, Bruno Vellas, Sandrine Andrieu and the REAL-FR Study Group and the 3C Study Group
DOI: 10.2174/1567205013666161108114850

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Potential for Stem Cells Therapy in Alzheimer’s Disease: Do Neurotrophic Factors Play Critical Role?

Volume: 14   Issue: 2
Pp: 208-220
Parul Bali, Debomoy K. Lahiri, Avijit Banik, Bimla Nehru and Akshay Anand
DOI: 10.2174/1567205013666160314145347

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Role of Artificial Intelligence Techniques (Automatic Classifiers) in Molecular Imaging Modalities in Neurodegenerative Diseases

Volume: 14   Issue: 2
Pp: 198-207
Silvia Cascianelli, Michele Scialpi, Serena Amici, Nevio Forini, Matteo Minestrini, Mario Luca Fravolini, Helmut Sinzinger, Orazio Schillaci and Barbara Palumbo
DOI: 10.2174/1567205013666160620122926

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Non-Ceruloplasmin Copper Distinguishes A Distinct Subtype of Alzheimer’s Disease: A Study of EEG-Derived Brain Activity

Volume: 13   Issue: 12
Pp: 1374-1384
Franca Tecchio, Fabrizio Vecchio, Mariacarla Ventriglia, Camillo Porcaro, Francesca Miraglia, Mariacristina Siotto, Paolo M. Rossini, Mauro Rongioletti and Rosanna Squitti
DOI: 10.2174/1567205013666160603001131

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MCI Patients in Europe: Medication and Comorbidities. The DESCRIPA Study

Volume: 13   Issue: 12
Pp: 1407-1413
Magda Tsolaki, Vasileios Papaliagkas, Giovanni Frisoni, Roy Jones, Jacques Touchon, Luiza Spiru, Bruno Vellas, Frans Verhey, Bengt Winblad, Pieter Jelle Visser and on behalf of the DESCRIPA Study Group
DOI: 10.2174/1567205013666160603002704

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The Association Between Alcohol Use and the Progression of Alzheimer’s Disease

Volume: 13   Issue: 12
Pp: 1356-1362
Devorah Heymann, Yaakov Stern, Stephanie Cosentino, Oksana Tatarina-Nulman, Jhedy N. Dorrejo and Yian Gu
DOI: 10.2174/1567205013666160603005035

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Drug Development of Small-Molecule Inhibitors of AD-Relevant Kinases as Novel Perspective Multitargeted Approach

Volume: 13   Issue: 12
Pp: 1330-1336
V. Tell, I. Hilbrich, M. Holzer, Frank Totzke, Christoph Schachtele, Inna Slynko, Wolfgang Sippl and A. Hilgeroth
DOI: 10.2174/1567205013666160615091821

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DNA Double Strand Breaks: A Common Theme in Neurodegenerative Diseases

Volume: 13   Issue: 11
Pp: 1208-1218
Daniela Merlo, Cristiana Mollinari, Mauro Racaniello, Enrico Garaci and Alessio Cardinale
DOI: 10.2174/1567205013666160401114915

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Alzheimer’s Disease Genetic Risk Factor APOE-ε4 Also Affects Normal Brain Function

Volume: 13   Issue: 11
Pp: 1200-1207
Amanda M. Di Battista, Nicolette M. Heinsinger and G. William Rebeck
DOI: 10.2174/1567205013666160401115127

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Ceramide and Sphingosine-1-Phosphate in Cell Death Pathways : Relevance to the Pathogenesis of Alzheimer's Disease

Volume: 13   Issue: 11
Pp: 1232-1248
Sankha Shubhra Chakrabarti, Aritri Bir, Jit Poddar, Maitrayee Sinha, Anirban Ganguly and Sasanka Chakrabarti
DOI: 10.2174/1567205013666160603004239

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Neuropsychiatric Disturbances in Mild Cognitive Impairment (MCI): A Systematic Review of Population-Based Studies

Volume: 13   Issue: 10
Pp: 1066-1082
Cristiano A. Köhler, Thaís F. Magalhaes, Joao M.M.P. Oliveira, Gilberto S. Alves, Christian Knochel, Viola Oertel-Knöchel, Johannes Pantel and André F. Carvalho
DOI: 10.2174/1567205013666160502123129

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Glial Cells – The Key Elements of Alzheimer´s Disease

Volume: 13   Issue: 8
Pp: 894-911
David Dzamba, Lenka Harantova, Olena Butenko and Miroslava Anderova
DOI: 10.2174/1567205013666160129095924

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Lithium, a Therapy for AD: Current Evidence from Clinical Trials of Neurodegenerative Disorders

Volume: 13   Issue: 8
Pp: 879-886
Orestes V. Forlenza, Ivan Aprahamian, Vanessa J. de Paula and Tomas Hajek
DOI: 10.2174/1567205013666160219112854

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Metabolomic-Driven Elucidation of Serum Disturbances Associated with Alzheimer's Disease and Mild Cognitive Impairment

Volume: 13   Issue: 6
Pp: 641-653
Raúl González-Domínguez, Francisco Javier Rupérez, Tamara García-Barrera, Coral Barbas and José Luis Gómez-Ariza
DOI: 10.2174/1567205013666160129095138

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Oral Triphenylmethane Food Dye Analog, Brilliant Blue G, Prevents Neuronal Loss in APPSwDI/NOS2-/- Mouse Model open access plus

Volume: 13   Issue: 6
Pp: 663-677
Jacob A. Irwin, Alev Erisir and Inchan Kwon
DOI: 10.2174/1567205013666160208142456

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Serum Levels of Progranulin Do Not Reflect Cerebrospinal Fluid Levels in Neurodegenerative Disease

Volume: 13   Issue: 6
Pp: 654-662
Carlo Wilke, Frank Gillardon, Christian Deuschle, Evelyn Dubois, Markus A. Hobert, Jennifer Müller vom Hagen, Stefanie Krüger, Saskia Biskup, Cornelis Blauwendraat, Michael Hruscha, Stephan A. Kaeser, Peter Heutink, Walter Maetzler and Matthis Synofzik
DOI: 10.2174/1567205013666160314151247

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A Spherical Brain Mapping of MR Images for the Detection of Alzheimer’s Disease

Volume: 13   Issue: 5
Pp: 575-588
F. J. Martinez-Murcia, J. M. Górriz, J. Ramírez, A. Ortiz and for the Alzheimer’s Disease Neuroimaging Initiative
DOI: 10.2174/1567205013666160314145158

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Functional Connectivity Hubs Could Serve as a Potential Biomarker in Alzheimer’s Disease: A Reproducible Study

Volume: 12   Issue: 10
Pp: 974-983
Xiuchao Sui, Maohu Zhu, Yue Cui, Chunshui Yu, Jing Sui, Xinqing Zhang, Jieqiong Liu, Yunyun Duan, Zengqiang Zhang, Luning Wang, Xi Zhang and Tianzi Jiang
DOI: 10.2174/1567205012666150710111615

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Differential Expression of Ribosomal Genes in Brain and Blood of Alzheimer’s Disease Patients

Volume: 12   Issue: 10
Pp: 984-989
Lucas Rasmussen, Roger W. de Labio, Gustavo A. Viani, Elizabeth Chen, Joao Villares, Paulo-Henrique Bertolucci, Thais S. Minett, Gustavo Turecki, Danielle Cecyre, Sandra A. Drigo, Marilia C. Smith and Spencer L.M. Payao
DOI: 10.2174/1567205012666151027124017

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Lipid-Based Diets Improve Muscarinic Neurotransmission in the Hippocampus of Transgenic APPswe/PS1dE9 Mice

Volume: 12   Issue: 10
Pp: 923-931
Helena Janickova, Vladimir Rudajev, Eva Dolejsi, Hennariikka Koivisto, Jan Jakubik, Heikki Tanila, Esam E. El-Fakahany and Vladimir Dolezal
DOI: 10.2174/1567205012666151027130350

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Serum Fragments of Tau for the Differential Diagnosis of Alzheimer's Disease

Volume: 12   Issue: 9
Pp: 829-836
D. Inekci, K. Henriksen, T. Linemann, M.A. Karsdal, A. Habib, C. Bisgaard, F.B. Eriksen and O.J. Vilholm
DOI: 10.2174/1567205012666150710111211

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Cognitive Improvement by Photic Stimulation in a Mouse Model of Alzheimer’s Disease

Volume: 12   Issue: 9
Pp: 860-869
Yu Zhang, Furong Wang, Xianwen Luo, Li Wang, Peng Sun, Min Wang, Yongsheng Jiang, Jingyu Zou, Osamu Uchiumi, Ryo Yamamoto, Tokio Sugai, Kenji Yamamoto and Nobuo Kato
DOI: 10.2174/1567205012666150710115755

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Identification of Small Molecule Inhibitors of Tau Aggregation by Targeting Monomeric Tau As a Potential Therapeutic Approach for Tauopathies open access plus

Volume: 12   Issue: 9
Pp: 814-828
Marcus Pickhardt, Thomas Neumann, Daniel Schwizer, Kari Callaway, Michele Vendruscolo, Dale Schenk, Peter St. George-Hyslop, Eva M. Mandelkow, Christopher M. Dobson, Lisa McConlogue, Eckhard Mandelkow and Gergely Toth
DOI: 10.2174/156720501209151019104951

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Oral Administration of Thioflavin T Prevents Beta Amyloid Plaque Formation in Double Transgenic AD Mice

Volume: 12   Issue: 9
Pp: 837-846
Sumit Sarkar, James Raymick, Balmiki Ray, Debomoy K. Lahiri, Merle G. Paule and Larry Schmued
DOI: 10.2174/156720501209151019105647

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Neurobiology of Alzheimer’s Disease: Integrated Molecular, Physiological, Anatomical, Biomarker, and Cognitive Dimensions open access plus

Volume: 12   Issue: 8
Pp: 712-722
Joel Raskin, Jeffrey Cummings, John Hardy, Kory Schuh and Robert A. Dean
DOI: 10.2174/1567205012666150701103107

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Mediterranean Diet and Risk of Dementia

Volume: 12   Issue: 8
Pp: 736-744
Apostolos Safouris, Georgios Tsivgoulis, Theodoros N. Sergentanis and Theodora Psaltopoulou
DOI: 10.2174/1567205012666150710114430

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Insulin Resistance as Common Molecular Denominator Linking Obesity to Alzheimer’s Disease

Volume: 12   Issue: 8
Pp: 723-735
Domenico Nuzzo, Pasquale Picone, Sara Baldassano, Luca Caruana, Elisa Messina, Antonella Marino Gammazza, Francesco Cappello, Flavia Mulè and Marta Di Carlo
DOI: 10.2174/1567205012666150710115506

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Inhibitory Activity of Curcumin Derivatives Towards Metal-Free and Metal-Induced Amyloid-β Aggregation

Volume: 12   Issue: 5
Pp: 415-423
Akiko Kochi, Hyuck Jin Lee, Sashiprabha M. Vithanarachchi, Vediappen Padmini, Matthew J. Allen and Mi Hee Lim
DOI: 10.2174/1567205012666150504150125

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Syntheses and Evaluation of Asymmetric Curcumin Analogues as Potential Multifunctional Agents for the Treatment of Alzheimer’s Disease

Volume: 12   Issue: 5
Pp: 403-414
Peng Zhai, Chun-Li Xia, Jia-Heng Tan, Ding Li, Tian-Miao Ou, Shi-Liang Huang, Lian-Quan Gu and Zhi-Shu Huang
DOI: 10.2174/1567205012666150504151120

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Alzheimer’s Disease, Astrocytes and Kynurenines

Volume: 12   Issue: 5
Pp: 462-480
Livia Dezsi, Bernadett Tuka, Diana Martos and Laszlo Vecsei
DOI: 10.2174/156720501205150526114000

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Functional Activities Questionnaire Items that Best Discriminate and Predict Progression from Clinically Normal to Mild Cognitive Impairment

Volume: 12   Issue: 5
Pp: 493-502
Gad A. Marshall, Amy S. Zoller, Natacha Lorius, Rebecca E. Amariglio, Joseph J. Locascio, Keith A. Johnson, Reisa A. Sperling, Dorene M. Rentz and for the Alzheimer’s Disease Neuroimaging Initiative
DOI: 10.2174/156720501205150526115003

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Childhood and Adulthood Rural Residence Increases the Risk of Dementia: NEDICES Study

Volume: 12   Issue: 4
Pp: 350-357
Israel Contador, Felix Bermejo-Pareja, Veronica Puertas-Martin and Julian Benito-Leon
DOI: 10.2174/1567205012666150324181327

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Running Exercise Reduces Myelinated Fiber Loss in the Dentate Gyrus of the Hippocampus in APP/PS1 Transgenic Mice

Volume: 12   Issue: 4
Pp: 377-383
Fenglei Chao, Lei Zhang, Yanmin Luo, Qian Xiao, Fulin Lv, Qi He, Chunni Zhou, Yi Zhang, Lin Jiang, Rong Jiang, Hengwei Gu and Yong Tang
DOI: 10.2174/1567205012666150325183011

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Clinical Relevance of Apolipoprotein E Genotyping Based on a Family History of Alzheimer's Disease

Volume: 12   Issue: 3
Pp: 210-217
Hilmar K. Luckhoff, Theresa Brand, Dawid P. van Velden, Martin Kidd, Leslie R. Fisher, Susan J. van Rensburg and Maritha J. Kotze
DOI: 10.2174/1567205012666150302154354

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Genetic Markers in Biological Fluids for Aging-Related Major Neurocognitive Disorder open access plus

Volume: 12   Issue: 3
Pp: 200-209
S.A. Castro-Chavira, T. Fernández, H. Nicolini, S. Diaz-Cintra and R.A. Prado-Alcalá
DOI: 10.2174/1567205012666150302155138

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Evaluating High-Dose Rivastigmine Patch in Severe Alzheimer’s Disease: Analyses with Concomitant Memantine Usage as a Factor promotion: free to download

Volume: 12   Issue: 1
Pp: 53-60
George T. Grossberg, Martin R. Farlow, Xiangyi Meng and Drew M. Velting
DOI: 10.2174/1567205011666141218122835

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Beneficial Effects of the β-Secretase Inhibitor GRL-8234 in 5XFAD Alzheimer’s Transgenic Mice Lessen During Disease Progression promotion: free to download

Volume: 12   Issue: 1
Pp: 13-21
Latha Devi, Jordan Tang and Masuo Ohno
DOI: 10.2174/1567205012666141218125042

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The Effects of Different Antioxidants on the Activity of Cerebrocortical MnSOD and Na,K-ATPase from post mortem Alzheimer’s Disease and Age-matched Normal Brains promotion: free to download

Volume: 11   Issue: 1
Pp: 79-85
C. Kairane, R. Mahlapuu, K. Ehrlich, M. Zilmer and U. Soomets
DOI: 10.2174/15672050113106660179

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