Endocrine, Metabolic & Immune Disorders - Drug Targets

(Formerly Current Drug Targets - Immune, Endocrine & Metabolic Disorders)

Editor-in-Chief:

Emilio Jirillo
Department of Basic Medical Sciences Neuroscience and Sensory Organs
University of Bari “Aldo Moro”
Bari
Italy

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Articles Ahead of Print

Role of Subclinical Iatrogenic Hyperthyroidism in the Setting of Heart Disease and Arrhythmic Burden

Volume:20
Sandra Mastroianno, Giuseppe Di Stolfo*, Angela Maggio, Michele Pacilli, Domenico Rosario Potenza, Raimondo Massaro, Giovanni De Luca and Aldo Russo

Insulin Autoimmune Syndrome After Exposure to Clopidogrel: A Case Report

Volume:20
Yihong Jiang*, Lihua Wang, Fanghong Shi, Huan Zhou, Jun Zheng, Jie Cai, Shuang Yang, Jing Ma and Wei Liu

Plasma Cytokine Levels in Overweight Versus Obese Disease-free Perimenopausal Women

Volume:20
Anna Cyntia Brandão Nascimento Maniçoba, Leonardo Victor Galvão-Moreira, Izabella Mikaella Souza Campos D'Albuquerque, Haissa Oliveira Brito, Johnny Ramos do Nascimento, Flávia Raquel Fernandes do Nascimento, Maria do Carmo Lacerda Barbosa, Rui Miguel Gil da Costa, Maria do Desterro Soares Brandão Nascimento, Manuel dos Santos Faria and Luciane Maria Oliveira Brito*

The Treatment of Prednisone in Mild Diabetic Rats: Biochemical Parameters and Cell Response

Volume:19
Mariana Pirani Rocha Machado, Aline Zanatta Schavinski, Amanda Lima Deluque, Gustavo Tadeu Volpato and Kleber Eduardo Campos*

The Effects of Resveratrol on Oxidative Stress Markers: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

Volume:19
Mahsa Omidian, Mina Abdolahi, Elnaz Daneshzad, Mohsen Sedighiyan, Mohadeseh Aghasi, Hamed Abdollahi, Parisa Omidian, Sasan Dabiri and Maryam Mahmoudi*

Nickel and Oxidative Stress: Cell Signaling Mechanisms and Protective Role of Vitamin C

Volume:19
Swastika Das, R. Chandramouli Reddy, Kailash S. Chadchan, Arun J. Patil, M. S. Biradar and Kusal K.Das*

Neurotransmitters and Behavioral Alterations Induced by Nickel Exposure

Volume:19
María Isabel Martínez-Martínez , Isabel Muñoz-Fambuena and Omar Cauli *

The Effect of Stem Cell Transplantation Therapy for Post Viral Chronic Liver Cell Failure on Associated Type II Diabetes Mellitus: A Pilot Study

Volume:19
Tamer Haydara, Mostafa Gabr, Mohamed Abofreikha, Abeer Bahnasy, Hosny Salama, Mohammed Elhendawy, Mahmoud Elkadeem and Sherief Abd-Elsalam*

Variation in the Level of Thyroid Markers in Association with Inflammation in Patients with Type 2 Diabetes

Volume:19
Khalid Siddiqui*, Teena P. George , Salini Scaria Joy and Muhammad Mujammami

Caveolin-1 Regulates CCL5 and PPARγ Expression in Nthy-ori 3-1 Cells: Possible Involvement of Caveolin-1 and CCL5 in the Pathogenesis of Hashimoto’s Thyroiditis

Volume:19
Baocui Liu, Tingting Zheng, Liyang Dong, Chaoming Mao*, Chengcheng Xu, Xiao Mou, Xuan Luo, Qingyan Lu, Xin Dong, Jiameng Liu, Ping Kang, Chao Ding, Yichuan Xiao and Peng Jiang

Effect of Diets with Different Lipid’s Sources On Serum and Brain Fatty Acids Profile. Experimental Model

Volume:19
Nora H. Slobodianik, Paula D. Perris, María Cecilia Mambrin, Inés Fernandez and María Susana Feliu*

Interleukin 1-beta is Linked to Chronic Low-grade Inflammation and Cardiovascular Risk Factors in Overweight Adolescents

Volume:19
Gisele A. Amaral, Josilene D. Alves, Adenilda C. Honorio-França, Danny L. Fagundes, Gabriel Gomes Araujo, Nubia S. Lobato, Victor V. Lima and Fernanda R. Giachini*

Is the Cerebellum Involved in the Nervous Control of the Immune System Function?

Volume:19
Anna Rizzi, Matteo Saccia and Vincenzo Benagiano*

Association of HLA-DRB1 and -DQ Alleles and Haplotypes with Type 1 Diabetes in Jordanians

Volume:19
Sawsan I. Khdair*, Wassan Jarrar, Yazun Bashir Jarrar, Safa’a Bataineh and Omar Al-Khaldi

Study of Antihypertensive Activity of Anvillea radiata in L-Name-Induced Hypertensive Rats and HPLC-ESI-MS Analysis

Volume:19
Mourad Akdad, Mohammed Ajebli, Andrea Breuer, Farid Khallouki, Robert W Owen and Mohamed Eddouks*

The Association of Potassium Status with Parameters of Glucose Metabolism is influenced by Age in Adults

Volume:19
Ibrahim Elmadfa, Alexa L Meyer, Verena Hasenegger, Thomas Moeslinger and Cem Ekmekcioglu*

Congestive Heart Failure and Thyroid Dysfunction: The Role of the Low T3 Syndrome and Therapeutic Aspects

Volume:19
Giuseppe Lisco *, Anna De Tullio, Massimo Iacoviello and Vincenzo Triggiani

Hepatocyte Growth Factor Attenuates the Development of TGF-β1- Induced EndMT Through Down-Regulating the Notch Signaling

Volume:19
Ruiping Yang, Fan Yang, Yingchun Hu, Muhu Chen, Ying Liu, Jinpeng Li and Wu Zhong*

Insulin Resistance in Apolipoprotein M Knockout Mice is Mediated by the Protein Kinase Akt Signaling Pathway

Volume:19
Shuang Yao, Jun Zhang, Yuxia Zhan, Yuanping Shi, Yang Yu, Lu Zheng, Ning Xu* and Guanghua Luo*

Thyroid Disorders and Prognosis in Chronic Heart Failure: A Long-Term Follow-Up Study

Volume:19
Massimo Iacoviello, Giuseppe Parisi, Margherita Ilaria Gioia, Dario Grande, Caterina Rizzo, Pietro Guida, Francesco Lisi, Vito Angelo Giagulli, Brunella Licchelli, Francesca Di Serio, Edoardo Guastamacchia and Vincenzo Triggiani

Arg753Gln Polymorphisms in the Toll-Like Receptor 2 Gene are Associated with Cytomegalovirus Infection in Egyptian Bone Marrow Recipients

Volume:19
Sobhy Hassab El-Nabi, Samia Sayed, Mohamed A. Abd-Elhafez, Mohamed Elfiky, Ahmed E. Abdel Moneim and Islam El-Garawani

Diet: A Source of Endocrine Disruptors

Volume:19
Hina Rashid, Saad S Alqahtani and Saeed Alshahrani*

The Preventive Effect of IL-1beta Antagonist on Diabetic Peripheral Neuropathy

Volume:19
Zheng Hangping , Han Ling, Ji Lijin, Zhao Wenting, Liu Xiaoxia, Zhang Qi, Zhu Xiaoming, Li Qingchun, Li Yiming, Xiong Qian, Hu Ji, Lu Bin* and Zhang Shuo*

Gender Dysphoria, Eating Disorders and Body Image: An Overview

Volume:19
W. Milano, P. Ambrosio, F. Carizzone, V. De Biasio, G. Foggia and A. Capasso*

Evaluation of Salivary Antioxidants and Oxidative Stress Markers in Type 2 Diabetes Mellitus: A Retrospective Cohort Study

Volume:19
Shima Fathi, Shiva Borzouei, Mohammad Taghi Goodarzi, Jalal Poorolajal and Fatemeh Ahmadi-Motamayel*

The Herbicide Glyphosate and Its Apparently Controversial Effect on Human Health: An Updated Clinical Perspective

Volume:19
Carlo Caiati*, Paolo Pollice, Stefano Favale and Mario Erminio Lepera

The “Scourge of the Renaissance”. A Short Review About Treponema pallidum infection

Volume:19
Luigi Santacroce*, Lucrezia Bottalico, Skender Topi, Francesca Castellaneta and Ioannis Alexandros Charitos

Interleukin -17 Serum Levels and Polymorphisms in Acute Kidney Injury Patients

Volume:19
Mahsa Rahimzadeh, Hossein Montazerghaem, Sara Aghakhani Chegeni and Nadereh Naderi*

Dietary Melatonin Protects Against Behavioural, Metabolic, Oxidative, and Organ Morphological Changes in Mice that are Fed High-Fat, High- Sugar Diet

Volume:19
Adejoke Yetunde Onaolapo, Ebenezer Oladimeji Adebisi, Adegbayi Emmanuel Adeleye, Anthony Tope Olofinnade and Olakunle James Onaolapo*

Anti-diabetic and Angio-protective Effect of Guluronic Acid (G2013) as a New Nonsteroidal Anti-inflammatory Drug in the Experimental Model of Diabetes

Volume:19
Seyed Shahabeddin Mortazavi-Jahromi, Shahab Alizadeh, Mohammad Hassan Javanbakht* and Abbas Mirshafiey*

Withdrawn: Effect of Fractions of Vernonia amygdalina on Some Biochemical Parameters in High Fat Diet-Induced Obese Rats

Volume:19
Chima A. Egedigwe-Ekeleme, Ifeoma I. Ijeh, Polycarp N. Okafor, Chinedum O. Eleazu* and Uchenna O. Egedigwe

Metformin: Up to Date

Volume:19
Silvia Sciannimanico, Franco Grimaldi, Fabio Vescini, Giovanni De Pergola , Massimo Iacoviello, Brunella Licchelli , Edoardo Guastamacchia , Vito Angelo Giagulli and Vincenzo Triggiani *

The Association of Metabolic Syndrome and Psoriasis: A Systematic Review and Meta-Analysis of Observational Study

Volume:19
Saumya Choudhary, Dibyabhabha Pradhan, Anamika Pandey, Mohd. Kamran Khan, Rohit Lall, V Ramesh, Poonam Puri, Arun Kumar Jain and George Thomas*

Immune-Inflammation in Atherosclerosis: A New Twist in the Old Tale

Volume:19
Atefe Ghamar Talepoor, Hamed Fouladseresht, Shahdad Khosropanah and Mehrnoosh Doroudchi*

A Review on the Effects of New Anti-Diabetic Drugs on Platelet Function

Volume:19
Habib Yaribeygi, Stephen L. Atkin, Tannaz Jamialahmadi and Amirhossein Sahebkar*

The Expression of Hormone Receptors as a Gateway Toward Understanding Endocrine Actions in Female Pelvic Floor Muscles

Volume:19
Francisco Castelán*, Estela Cuevas-Romero and Margarita Martínez-Gómez

Mechanism Underlying the Formation of a Cluster of Metabolic Syndrome

Volume:19
Svetlana Igorevna Kseneva, Elena Valentinovna Borodulina, Vladimir Vasilievich Udut and Vladimir Petrovich Fisenko

Gender-Dependent Association of Vitamin D Deficiency with Obesity and Hypercholesterolemia (LDLC) in Adults

Volume:19
Norah Almesri, Nagalla S Das, Muhallab E. Ali, Khalid Gumaa and Hayder A. Giha*

Differential Expression of Resistant and Efflux Pump Genes in MDR-TB Isolates

Volume:19
Manaf Al Matar*, Işıl Var, Begüm Kayar and Fatih Köksal

Our Little Friends with Big Roles: Alterations of the Gut Microbiota in Thyroid Disorders

Volume:19
Hanieh-Sadat Ejtahed, Pooneh Angorani, Ahmad-Reza Soroush, Seyed-Davar Siadat, Nooshin Shirzad, Shirin Hasani-Ranjbar* and Bagher Larijani

Can Anti-Thyroid Antibodies Influence the Outcome of Primary Chronic Immune Thrombocytopenia in Children?

Volume:19
Paola Giordano, Maurizio Delvecchio, Giuseppe Lassandro, Federica Valente, Valentina Palladino, Mariangela Chiarito, Malgorzata Wasniewska and Maria Felicia Faienza*

Diagnostic Approach to The Patients with Suspected Primary Immunodeficiency

Volume:19
Marzieh Tavakol, Mahnaz Jamee, Gholamreza Azizi*, Homa Sadri, Yasser Bagheri, Majid Zaki-Dizaji, Fatemeh Sadat Mahdavi, Farhad Jadidi-Niaragh, Sanaz Tajfirooz, Ali N. Kamali, Fatemeh Aghamahdi, Shahab Noorian, Habibeh Taghavi Kojidi, Mehdi Mosavian, Rahman Matani, Elahe Dolatshahi, Kumars Porrostami, Nasrin Elahimehr, Marzie Fatemi-Abhari, Laleh Sharifi, Reza Arjmand, Sabahat Haghi, Hamed Zainaldain, Reza Yazdani, Mohammadreza Shaghaghi, Hassan Abolhassani and Asghar Aghamohammadi

Prolonged Adrenal Insufficiency After the Discontinuation of Mitotane Therapy

Volume:19
Leonardo Muratori , Anna Pia, Giuseppe Reimondo, Chiara Pisano, Anna La Salvia, Soraya Puglisi, Giorgio Vittorio Scagliotti and Paola Sperone

Blockade of Renin Angiotensin System Ameliorates the Cardiac Arrythmias and Sympathetic Neural Remodeling in Hearts of Type 2 DM Rat Model

Volume:19
Yomna M. Yehya, Abdelaziz M. Hussein*, Khaled Ezam, Elsayed A. Eid, Eman M. Ibraheim, Mohamed A.F.E. Sarhan, Aya Elsayed and Mohamed E. Sarhan

Monitoring and Evaluation of Thyroid Function Tests, Serum Electrolytes and Creatinine Levels Before and After I131 Therapy

Volume:19
Rubaida Mehmood*, Muhammed Saqib Khan, Sajid Hussain, Akhlaque Ahmed, Farhatul-Ain Arshad and Rubina Mukhtar

Anti-cancerous Effect of Rutin Against HPV-C33A Cervical Cancer Cells via G0/G1 Cell Cycle Arrest and Apoptotic Induction

Volume:19
Fahad Khan, Pratibha Pandey*, Tarun Kumar Upadhyay, Asif Jafri, Niraj Kumar Jha, Rashmi Mishra and Vineeta Singh

Modulation of Hematological Indices of Normal and Alloxan-Induced Diabetic Rabbits by Aqueous Extract of Pleurotus tuberregium Sclerotia

Volume:19
Ifeanacho Mercy Onuekwuzu, Ikewuchi Catherine Chidinma* and Ikewuchi Jude Chigozie

Dimeric NGF Mimetic Attenuates Hyperglycaemia and DNA Damage in Mice with Streptozotocin-induced Early-stage Diabetes

Volume:19
Svetlana Yagubova, Aliy Zhanataev, Rita Ostrovskaya*, Еlena Anisina, Тatiana Gudasheva, Аndrey Durnev and Sergey Seredenin

Leishmaniasis and Autoimmunity in Patient with LPS-Responsive Beige-Like Anchor Protein (LRBA) Deficiency

Volume:19
Fereshte Salami, Afshin Shirkani*, Mohammad Shahrooei, Gholamreza Azizi, Reza Yazdani, Hassan Abolhassani and Asghar Aghamohammadi*

Medullary Thyroid Cancer with Paraganglioma-Like Pattern Diagnosed During Pregnancy: A Case Report and Literature Revision

Volume:19
Anna De Tullio, Giuseppe Lisco, Loren Duda, Giuseppina Renzulli and Vincenzo Triggiani*

UCP2, SHBG, Leptin, and T3 Levels are Associated with Resting Energy Expenditure in Obese Women

Volume:19
Hamideh Pishva*, Somaye Ahmadi, Mohammad Reza Eshraghian and Mehdi Hedayati

Aligned Expression of IFI16 and STING Genes in RRMS Patients’ Blood

Volume:19
Sobhan Helbi, Behnam Ravanbakhsh, Mohammad Karimi, Wesam Kooti* and Nahid Jivad*

African Walnuts (Tetracarpidium conophorum) Modulate Hepatic Lipid Accumulation in Obesity via Reciprocal Actions on HMG-CoA Reductase and Paraoxonase

Volume:19
Daniel Ejim Uti, Item Justin Atangwho*, Eyong Ubana Eyong, Grace Ufedo Umoru, Godwin Eneji Egbung, Solomon Oladapo Rotimi and Victor Udo Nna

A Historical Review of Persian Medicine Studies into Saliva Manifestations for Potential Applications for Diagnosis and Management of Metabolic Syndrome

Volume:19
Fatemeh Hakimi, Rasool Choopani, Majid Asghari, Hasan Namdar, Elham Parsa, Parisa Jafari and Mina Movahhed*

SRC-3/AIB-1 may Enhance Hepatic NFATC1 Transcription and Mediate Inflammation in a Tissue-Specific Manner in Morbid Obesity

Volume:19
Athina Chasapi*, Konstantinos Balampanis, Anna Tanoglidi, Eleni Kourea, George I. Lambrou, Vaia Lambadiari, Fotios Kalfarentzos, Erifili Hatziagelaki, Maria Melachrinou and Georgia Sotiropoulou-Bonikou

Serum Vitamin D Levels in Children with Immune Thrombocytopenia

Volume:19
Giuseppe Lassandro, Francesco Carriero, Viviana Palmieri, Valentina Palladino, Anna Amoruso, Maria Filomena Gallone, Giovanni Carlo Del Vecchio*, Silvio Tafuri, Giovanna Russo and Paola Giordano*