Letters in Drug Design & Discovery

Editor-in-Chief
K. Kuca
University of Hradec Kralove
Hradec Kralove
Czech Republic

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Volume:9   Issue: 10
Pp: i-iv

DOI: 10.2174/157018081120905000i

Acknowledgement promotion: free to download

Volume:9   Issue: 10
Pp: v-v

DOI: 10.2174/157018081120905000v

Novel Non-Competitive Antagonists of Kainate GluK1/GluK2 Receptors

Volume:9   Issue: 10
Pp: 891-898
Agnieszka Anna Kaczor, Christiane Kronbach, Klaus Unverferth, Kalevi Pihlaja, Kirsti Wiinamaki, Jari Sinkkonen, Urszula Kijkowska-Murak, Tomasz Wrobel, Tomasz Stachal and Dariusz Matosiuk
DOI: 10.2174/1570180811209050891

Pharmacophore Generation and 3D-QSAR of Novel 2-(quinazolin-4- ylamino)-[1,4] Benzoquinone Derivatives as VEGFR-2 Inhibitors

Volume:9   Issue: 10
Pp: 899-914
Mahesh Kumar Teli, Pradeep Hanumanthappa and Rajanikant G. Krishnamurthy
DOI: 10.2174/1570180811209050899

QSAR Studies of PTP1B Inhibitors: 1, 2-Naphthoquinone Derivatives

Volume:9   Issue: 10
Pp: 915-925
Feng Luan, Xuan Xu, Huitao Liu, Maria Natalia Dias Soeiro Cordeiro and Xiaoyun Zhang
DOI: 10.2174/1570180811209050915

3-(Adamantan-1-yl)-4-hydroxybenzyl Substituted Purines and Pyrimidines: Synthesis and Cytotoxic Activity

Volume:9   Issue: 10
Pp: 926-933
Nageswara Rao Kode, Dakshinamurthy Devangachinta and Shashikant Phadtare
DOI: 10.2174/1570180811209050926

Microwave Assisted Synthesis, Characterization of Some New Isatin and Thiophene Derivatives as Cytotoxic and Chemopreventive Agents

Volume:9   Issue: 10
Pp: 934-941
Kiran Gangarapu, Sarangapani Manda, Sreekanth Thota, Rajeshwar Yerra, Subhas S. Karki, Jan Balzarini, Erik De Clercq and Harukuni Tokuda
DOI: 10.2174/1570180811209050934

Synthesis and Cytotoxicity Evaluation of Some Novel 3,5-disubstituted- 1,2,4-Oxadiazoles

Volume:9   Issue: 10
Pp: 942-946
M. Siva Nagi Reddy, B. Sailaja Kumari and B. Hari Babu
DOI: 10.2174/1570180811209050942

Halogen Substituents as an Effective Modulators of Antibacterial Activity of Substituted 1,2,4-triazole-3-thiones

Volume:9   Issue: 10
Pp: 947-952
Tomasz Plech, Monika Wujec, Urszula Kosikowska and Anna Malm
DOI: 10.2174/1570180811209050947

Antimycobacterial Agents: Synthesis and Biological Evaluation of Novel 4-(Substituted-phenyl)-6-methyl-2-oxo-N-(pyridin-2-yl)-1,2,3,4-tetrahydropyrimidine- 5-carboxamide Derivatives by Using One-pot Multicomponent Method

Volume:9   Issue: 10
Pp: 953-957
Abdulrahman I. Almansour, Mohamed Ashraf Ali, Sadath Ali, Ang Chee Wei, Yeong Keng Yoon, Rusli Ismail, Tan Soo Choon, Suresh Pandian, Raju Suresh Kumar, Natarajan Arumugam and Hasnah Osman
DOI: 10.2174/1570180811209050953

Exploring Nitrostyrene as a Scaffold for a New Class a of Monoamine Oxidase Inhibitors

Volume:9   Issue: 10
Pp: 958-961
Joana Reis, Catarina Oliveira, Nuno Milhazes, Dolores Vina and Fernanda Borges
DOI: 10.2174/1570180811209050958

Hydroxysafflor Yellow A Attenuates Renal Ischemia- Reperfusion Injury in a Rat Model

Volume:9   Issue: 10
Pp: 967-972
Weiran Chai, Wenhui Zhang, Zhu Jin, Yanqian Zheng, Peiyao Jin, Qiaoyan Zhang and Jianming Zhi
DOI: 10.2174/1570180811209050967