Letters in Drug Design & Discovery

Editor-in-Chief:

George Perry
University of Texas
San Antonio, TX
USA

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Volume:8   Issue:4
Pp: i-v

DOI: 10.2174/157018011794839457

The Antiangiogenic and Antitumoral Activity of Titanocene Y* In Vivo

Volume:8   Issue:4
Pp: 302-307
Iduna Fichtner, Diana Behrens, James Claffey, Anthony Deally, Brendan Gleeson, Siddappa Patil, Holger Weber and Matthias Tacke
DOI: 10.2174/157018011794839367

Synthesis of Some Coumarinyl Chalcones and their Antiproliferative Activity Against Breast Cancer Cell Lines

Volume:8   Issue:4
Pp: 308-311
Kuldeep Patel, Chandrabose Karthikeyan, Viswas Raja Solomon, N. S. Hari Narayana Moorthy, Hoyun Lee, Kapendra Sahu, Girdhar Singh Deora and Piyush Trivedi
DOI: 10.2174/157018011794839475

Synthesis and Characterization of some Novel Quinoxaline-2, 3-Dione Derivatives: A Preliminary Investigation on their Activity Against a Human Epithelial Carcinoma Cell Line

Volume:8   Issue:4
Pp: 317-320
Selvaraj Jubie, Rajamanickam Gayathri, Ammayappan Rajam Srividya, Rajagopal Kalirajan, Prabakaran Prabitha, Sundaram Sankar and Kannan Elango
DOI: 10.2174/157018011794839385

Vagus Nerve Stimulation as a Treatment for Refractory Epilepsy: A 15-Year Experience in an Italian Tertiary – Care Epilepsy Center

Volume:8   Issue:4
Pp: 321-329
Chiara Pizzanelli, Renato Galli, Filippo S. Giorgi, Alfonso Iudice, Enrica Bonanni, Veronica Pelliccia, Stella Jensen, Laura Manca, Bruno Lenzi, Ludovico Lutzemberger, Giuliano Parenti, Francesco Fornai and Luigi Murri
DOI: 10.2174/157018011794839394

Synthesis and Anxiolytic Activity of Some Novel 5-oxo-1, 4-oxazepine Derivatives

Volume:8   Issue:4
Pp: 330-338
Bothiana A. AbdelFattah, Maha M.A. Khalifa, Hend El-Sehrawi, Eman Fayed, Ashraf Bayoumi and Makarem Said
DOI: 10.2174/157018011794839448

3D-QSAR and Docking Studies of 4-morpholinopyrrolopyrimidine Derivatives as Potent mTOR Inhibitors

Volume:8   Issue:4
Pp: 339-354
Shao-Teng Wang, Yong Ai, Chu Tang, Fa-Jun Song and Ping-Hua Sun
DOI: 10.2174/157018011794839493

In Silico Identification of Small Molecule Mimetics of the Pro-Apoptotic BH3-Helix

Volume:8   Issue:4
Pp: 355-362
Melanie Fullbeck, Julia Hossbach, Ines S. Jaeger, Peter T. Daniel and Robert Preissner
DOI: 10.2174/157018011794839484

Molecular Docking with Trehalose-6 Phosphate Phosphatase: A Potential Drug Target of Filaral Parasite ‘Brugia malayi’

Volume:8   Issue:4
Pp: 363-370
Lakshminarayanan Karthik, Palayam Malathy, Annie Trinitta and Krishnasamy Gunasekaran
DOI: 10.2174/157018011794839402

Antimalarial Activity of an N-Alkyl Diamine

Volume:8   Issue:4
Pp: 371-374
Nicolli B. de Souza, Carlos A. M. Rezende, Marcela S. Toledo, Davi C. Lagatta, Raphaela V. T. de Oliveira, Cristiane F. da Costa, Adilson D. da Silva, Marcio J. M. Alves, Sonia M. N. Cupolilo, Mauro V. de Almeida and Clarice Abramo
DOI: 10.2174/157018011794839439

Antiviral Activity of 3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol and its Derivatives Against Influenza A(H1N1)2009 Virus

Volume:8   Issue:4
Pp: 375-380
Oleg V. Ardashov, Vladimir V. Zarubaev, Anna A. Shtro, Dina V. Korchagina, Konstantin P. Volcho, Nariman F. Salakhutdinov and Oleg I. Kiselev
DOI: 10.2174/157018011794839411

Transdermal Delivery of Acyclovir Sodium Via Carbopol Gels: Role of Chemical Permeation Enhancers

Volume:8   Issue:4
Pp: 381-389
Raju Jukanti, Ashok Mateti, Suresh Bandari and Prabhakar R Veerareddy
DOI: 10.2174/157018011794839420

Thermodynamic and Kinetic Aspects of the Lipid Peroxidation of Arachidonic Acid

Volume:8   Issue:4
Pp: 390-400
Claire Claire E. Tornow, Betsy Lau and M. C. Milletti
DOI: 10.2174/157018011794839376