Letters in Drug Design & Discovery

Editor-in-Chief
K. Kuca
University of Hradec Kralove
Hradec Kralove
Czech Republic

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Graphical Abstracts promotion: free to download

Volume:8   Issue: 2
Pp: i-iv

DOI: 10.2174/157018011794183879

Editorial [Hot Topic Progress in Fighting the Multidrug Resistance of Bacteria to Treatment (Guest Editor: Mihail-Lucian Pascu)] promotion: free to download

Volume:8   Issue: 2
Pp: 100-100
Mihail-Lucian Pascu
DOI: 10.2174/157018011794183734

BM0701: Antibiotic Transport and Efflux: New Strategies to Combat Bacterial Resistance (ATENS)

Volume:8   Issue: 2
Pp: 101-101
Jean-Marie Pages, Mihail-Lucian Pascu, Leonard Amaral, Ben Luisi, Gyorgy Hajos, Seamus Fanning and Peter Henderson
DOI: 10.2174/157018011794183824

Heterocyclic Compounds as MDR Modulators

Volume:8   Issue: 2
Pp: 102-113
Gyorgy Hajos, Katalin Jemnitz, Zsuzsanna Riedl, Daniella Takacs and Zsuzsa Veres
DOI: 10.2174/157018011794183815

Mechanisms of Antibiotic Resistance in Salmonella: Efflux Pumps, Genetics, Quorum Sensing and Biofilm Formation

Volume:8   Issue: 2
Pp: 114-123
Marta Martins, Matthew McCusker, Leonard Amaral and Seamus Fanning
DOI: 10.2174/157018011794183770

Time Stability Studies of Quinazoline Derivative Designed to Fight Drug Resistance Acquired by Bacteria

Volume:8   Issue: 2
Pp: 124-129
Andra Militaru, Adriana Smarandache, Abdallah Mahamoud, Sandrine Alibert, Jean-Marie Pages and Mihail-Lucian Pascu
DOI: 10.2174/157018011794183752

Thioridazine: Alternative and Potentially Effective Therapy of the XDRTB Patient

Volume:8   Issue: 2
Pp: 130-132
Leonard Amaral, Marta Martins and Miguel Viveiros
DOI: 10.2174/157018011794183860

Quorum Sensing Inhibition by Phenothiazines and Related Compounds

Volume:8   Issue: 2
Pp: 133-137
Zoltan Gabor Varga, Mira Agnes Szabo, Zsuzsanna Schelz, Erno Szegedi, Leonard Amaral and Jozsef Molnar
DOI: 10.2174/157018011794183789

Synthesis and Comparison of the Antitumor Activities of Steroids on ABCB1-transfected Mouse Lymphoma and Human Ovary Carcinoma

Volume:8   Issue: 2
Pp: 138-147
Julianna Serly, Iren Vincze, Csaba Somlai, Laszlo Hodoniczki and Jozsef Molnar
DOI: 10.2174/157018011794183833

Expression of P-gp, MRP, LRP, GST-π and TopoIIα and Acquired Resistance to Cisplatin in Human Lung Adenocarcinoma Cells

Volume:8   Issue: 2
Pp: 148-153
Jiarui Wang, Zhongzhou He, Lichuan Zhang, Encheng Li, Qiang Meng, Lijuan Zou, Joseph Molnar and Qi Wang
DOI: 10.2174/157018011794183743

Synthesis and Biological Evaluation of Gemfibrozil Chiral Analogues as Potential PPARα Agonists

Volume:8   Issue: 2
Pp: 154-158
Barbara De Filippis, Letizia Giampietro, Antonella Giancristofaro, Alessandra Ammazzalorso, Marialuigia Fantacuzzi, Cristina Maccallini, Michele Petruzzelli and Rosa Amoroso
DOI: 10.2174/157018011794183761

Integrated Web-Based ab initio Modeling Platform for G-protein Coupled Receptors

Volume:8   Issue: 2
Pp: 159-171
Govindan Subramanian, Manish Sud, Sam Billakanti and Adel Laoui
DOI: 10.2174/157018011794183798

Search of QSAR Models for Predicting the Antiprotozoal Activity and Cytotoxicity In Vitro of a Group of Pentamidine Analogous Compounds

Volume:8   Issue: 2
Pp: 172-180
Ramon Garcia-Domenech, Isabel Denise Manhenje, Yamileth Monje, Adassa Lopez-Gonzalez, Rafael Marco, Catalina Tacho and Jorge Galvez
DOI: 10.2174/157018011794183851

The Global Component-Target Network in Panax Ginseng C

Volume:8   Issue: 2
Pp: 181-188
Fan Zhang, Chun-Yang Li, En-Qin Wang, Wen-Wen Li, Qi-Jia Yu, Xin Wen, Jun-Jie Liu and Jin-Ku Bao
DOI: 10.2174/157018011794183842

Synthesis and Biological Evaluation of Some [1,2,4]Triazolo[3,4-b][1,3,4]Thiadiazoles and [1,2,4]Triazolo[3,4-b][1,3,4]Thiadiazines

Volume:8   Issue: 2
Pp: 189-200
Channamata Shankara Naveena, Boja Poojary, Chikkanna Chandrashekhar and Nalilu Suchetha Kumari
DOI: 10.2174/157018011794183806