Letters in Drug Design & Discovery

Editor-in-Chief:

George Perry
University of Texas
San Antonio, TX
USA

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Volume:7   Issue:7
Pp: i-iv

DOI: 10.2174/157018010791526331

Synthesis and Evaluation of Haloacetyl, α-Bromoacryloyl and Nitrooxyacetyl Benzo[b]furan and Benzo[b]thiophene Derivatives as Potent Antiproliferative Agents Against Leukemia L1210 and K562 Cells

Volume:7   Issue:7
Pp: 476-486
Romeo Romagnoli, Pier Giovanni Baraldi, Maria Dora Carrion, Carlota Lopez Cara, Alberto Casolari, Ernest Hamel, Enrica Fabbri and Roberto Gambari
DOI: 10.2174/157018010791526296

Synthesis of Xanthones and Benzophenones as Inhibitors of Tumor Cell Growth

Volume:7   Issue:7
Pp: 487-493
Elisangela Costa, Emilia Sousa, Nair Nazareth, Maria S.J. Nascimento and Madalena M.M. Pinto
DOI: 10.2174/157018010791526250

Reversion of Multidrug Resistance Using Self-Organized Nanoparticles Holding Both Doxorubicin and Targeting Moiety

Volume:7   Issue:7
Pp: 500-506
Yu Cao, Ying Gu, Lina Liu, Yi Yang, Peiguang Zhao, Ping Su, Liyan Liu, Chao Qi, Xia Lei and Changjiang Yang
DOI: 10.2174/157018010791526322

Biphenyl-Derivatives Possessing Tertiary Amino Groups as β-Secretase (BACE1) Inhibitors

Volume:7   Issue:7
Pp: 507-515
Simone Bertini, Elisa Ghilardi, Valentina Asso, Carlotta Granchi, Filippo Minutolo and Marco Macchia
DOI: 10.2174/157018010791526304

Potency of HI-6 to Reactivate Cyclosarin, Soman and Tabun Inhibited Acetylcholinesterase – In Vivo Study

Volume:7   Issue:7
Pp: 516-520
Jana Zdarova Karasova, Jiri Kassa, Miroslav Pohanka, Kamil Musilek and Kamil Kuca
DOI: 10.2174/157018010791526269

Triterpenes from Gloeophyllum odoratum as Potential Leads Towards Potent Thrombin Inhibitors

Volume:7   Issue:7
Pp: 521-527
Francesca Cateni, Vittorio Lucchini, Marko Anderluh, Paolo Martinuzzi, Marina Zacchigna, Andrej Piltaver and Bojan Doljak
DOI: 10.2174/157018010791526340

Molecular Modeling Suggests Cruzain Specificity for Peptide Primaquine Prodrugs

Volume:7   Issue:7
Pp: 528-533
Gustavo Henrique Goulart Trossini, Chung Man Chin, Carla Maria de Souza Menezes and Elizabeth Igne Ferreira
DOI: 10.2174/157018010791526287

Synthesis, Characterization by Means of IR, 1H, 13C - NMR and Biological Investigations on New Diorganotin Carboxylic Acid Derivatives

Volume:7   Issue:7
Pp: 534-540
Abderrahmane Yahyi, Abdelkader Et-Touhami, Rachid Yahyaoui and Rachid Touzani
DOI: 10.2174/157018010791526241

Inhibition of Pigment Epithelium-Derived Factor (PEDF) Augments Vascular Endothelial Growth Factor (VEGF)-Induced Recovery of Limb Perfusion after Ischemia in Klotho Mouse

Volume:7   Issue:7
Pp: 541-545
Ken Arima, Sho-ichi Yamagishi, Takanori Matsui, Yutaka Saito, Yoshio Katsuki, Ken-ichiro Sasaki, Yousuke Katsuda, Hisashi Kai and Tsutomu Imaizumi
DOI: 10.2174/157018010791526313