Letters in Drug Design & Discovery

Editor-in-Chief
K. Kuca
University of Hradec Kralove
Hradec Kralove
Czech Republic

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QSAR Study of Androstenedione Analogs as Aromatase Inhibitors

Volume:6   Issue: 8
Pp: 554-562
Aline A. Oliveira, Teodorico C. Ramalho and Elaine F.F. da Cunha
DOI: 10.2174/157018009789353464

Pretreatment with Huperzine A Protects Acetylcholinesterase in the Rat Brain Against Inhibition by VX and Russian VX

Volume:6   Issue: 8
Pp: 563-567
Jana Zdarova Karasova, Jiri Bajgar, Ladislav Novotny and Kamil Kuca
DOI: 10.2174/157018009789353419

3D-QSAR Study of Synthetic Furanones as Inhibitors of Quorum Sensing by Using CoMFA and CoMSIA Approach

Volume:6   Issue: 8
Pp: 568-574
Ping-Hua Sun, Zhao-Qi Yang, Mao-Kang Li, Wei-Min Chen, Qian Liu and Xin-Sheng Yao
DOI: 10.2174/157018009789353437

Design and Synthesis of Pterin Derivares as Nitric Oxide Synthase Inhibitors

Volume:6   Issue: 8
Pp: 575-578
Fei Ma, Ping Guo, Lixun Jiang, Mingsheng Feng, Jingbo Shi and Qizheng Yao
DOI: 10.2174/157018009789353482

Computer-Aided Drug Design of Pyranopyrazoles and Related Compounds for Checkpoint Kinase-1

Volume:6   Issue: 8
Pp: 579-584
Rahul Ramtekkar, Kandhasamy Kumarvel, Gnanasambandam Vasuki, K. Sekar and R. Krishna
DOI: 10.2174/157018009789353455

H3 Receptor Antagonists: Pharmacophore Modeling and its Implications (Supplementry Material)

Volume:6   Issue: 8
Pp: 585-594
A. B. Pramod, Sivasish Sindiri, M. Ravi Shashi Nayana, Santhosh Kumar Bairy, Ravi Shekar Ananthula, Ravikumar Muttineni, Madala Srividya and M. Kishore Kumar
DOI: 10.2174/157018009789353428

Design, Synthesis and Antiproliferative Activities of Artemisinin Derivatives Containing a Substituted Piperazine

Volume:6   Issue: 8
Pp: 595-598
Xue-Lin Yang, Dan Liu, Wei Wang, Lei Qu, Yong-Kui Jing and Lin-Xiang Zhao
DOI: 10.2174/157018009789353446

Identification of Potential Drug Targets of Leishmania infantum by In-silico Genome Analysis

Volume:6   Issue: 8
Pp: 620-622
Neeraj Suthar, Arun Goyal and Vikash Kumar Dubey
DOI: 10.2174/157018009789353491

Synthesis and Biological Evaluation of 5,6-Dihydro-benzo[c] acridin-7-ol Derivatives as Anti-Alzheimers Disease Drugs

Volume:6   Issue: 8
Pp: 623-628
Jinpei Zhou, Xiaowen Hu, Huibin Zhang, Hai Qian, Wenlong Huang, Fan Qi and Yanchun Zhang
DOI: 10.2174/157018009789353527

Synthesis and Characterization of Substituted Ethyl 2-(1-aminocyclobutyl)- 5-(benzoyloxy)-6-hydroxypyrimidine-4-carboxylate Derivatives as Antioxidant Agents

Volume:6   Issue: 8
Pp: 637-643
D. Asha, Manish Malviya, S. Chandrappa, C. T. Sadashiva, K. Vinaya, D. S. Prasanna and K. S. Rangappa
DOI: 10.2174/157018009789353509