Letters in Drug Design & Discovery

Editor-in-Chief
K. Kuca
University of Hradec Kralove
Hradec Kralove
Czech Republic

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CoMFA Study on Thiazolidine-2,4-diones for their Antihyperglycemic Activity

Volume:5   Issue: 2
Pp: 79-87
M. J. Nanjan, T. K. Praveen, B. Suresh, J. Vergheese, Bijoy J. Desai and B. R. Prashantha Kumar
DOI: 10.2174/157018008783928409

Artepillin C: A Review

Volume:5   Issue: 2
Pp: 88-92
Octavio Augusto Ceva Antunes, Joaquim Fernando Mendes da Silva and Gizelda Oliveira Duque Estrada
DOI: 10.2174/157018008783928436

Synthesis and Photobiological Properties of Bromo- and Alkoxymethyl Furocoumarins

Volume:5   Issue: 2
Pp: 93-103
Giampietro Viola, Marco Boccalini, Elena Fortunato, Francesco dall'Acqua and Stefano Chimichi
DOI: 10.2174/157018008783928481

New Peptidic Neuroprotectants Against NMDA Neurotoxicity: Syntheses and Biological Evaluations of Linear Complestatin Analogs

Volume:5   Issue: 2
Pp: 104-107
Ho-Joon Park, Seung-Woo Kim, Young-Gyun Shin, Yun-Jung Kim, Ja-Kyeong Lee, Suk Bin Kong and Sung-Hwa Yoon
DOI: 10.2174/157018008783928526

Phenylpyazoleanilides as a Potent Inhibitor of IL-15 Dependent T Cell Proliferation. Part 1: A New Class of Orally Available Immunomodulators open access plus

Volume:5   Issue: 2
Pp: 111-115
Hiroyuki Ushio, Seigo Ishibuchi, Kunitomo Adachi, Kouichi Oshita and Kenji Chiba
DOI: 10.2174/157018008783928427

Potent, Nonpeptide Inhibitors of Human Mast Cell Tryptase. 2. Investigation of the Carboxamide Portion of Spirocyclic Piperidine Amides

Volume:5   Issue: 2
Pp: 116-121
Michael J. Costanzo, Stephen C. Yabut, Han-Cheng Zhang, Kimberley B. White, Yuanping Wang, Lisa K. Minor, Brett A. Tounge, Alexander N. Barnakov, Frank Lewandowski, Cynthia Milligan, John C. Spurlino and Bruce E. Maryanoff
DOI: 10.2174/157018008783928418

Synthesis and Biological Activity of New Tricyclic Purine Derivatives Obtained by Intramolecular N-7 Alkylation

Volume:5   Issue: 2
Pp: 122-126
Arturene Maria Lino Carmo, Fernanda Gambogi Braga, Marcio Luiz De Paula, Ana Paula Ferreira, Henrique Couto Teixeira, Adilson David da Silva and Elaine Soares Coimbra
DOI: 10.2174/157018008783928535

Design and Synthesis of Novel Diaryl Heterocyclic Derivatives as Selective Cyclooxygenase-2

Volume:5   Issue: 2
Pp: 127-133
S. X. Li, X. D. Deng, F. L. Jiang, Y. J. Zhao, W. S. Xiao, X. Z. Kuang and X. M. Sun
DOI: 10.2174/157018008783928517

Mycophenolate Mofetil for the Treatment of Systemic Sclerosis

Volume:5   Issue: 2
Pp: 134-136
Manisha Naik, Max Shenin and Chris T. Derk
DOI: 10.2174/157018008783928454

Synthesis and Antitubercular Evaluation of N-[(E)-(hydroxy, methoxy and ethoxy-substituted-phenyl) Methylidene]isonicotinohydrazide Derivatives

Volume:5   Issue: 2
Pp: 137-140
Marcelle de L. Ferreira, Laura N. de F. Cardoso, Raoni S.B. Goncalves, Emerson T. da Silva, Maria Cristina S. Lourenco, Felipe R. Vicente and Marcus V.N. de Souza
DOI: 10.2174/157018008783928472

Antitumor Activity of Titanocene Y in Xenografted PC3 Tumors in Mice

Volume:5   Issue: 2
Pp: 141-144
Catherine M. Dowling, James Claffey, Sandra Cuffe, Iduna Fichtner, Clara Pampillon, Nigel J. Sweeney, Katja Strohfeldt, R. William G. Watson and Matthias Tacke
DOI: 10.2174/157018008783928463

Propofol and Systemic Inflammatory Response in Abdominal Aortic Surgery

Volume:5   Issue: 2
Pp: 148-151
Jose M. Rodriguez-Lopez and Francisco S. Lozano
DOI: 10.2174/157018008783928490