Letters in Drug Design & Discovery

Editor-in-Chief:

George Perry
University of Texas
San Antonio, TX
USA

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Galloyl Group is not Necessary for a Sedative Effect of Catechin Through GABAergic System

Volume:4   Issue:3
Pp: 163-167
Nami Adachi, Shozo Tomonaga, Rie Suenaga, D. Michael Denbow and Mitsuhiro Furuse
DOI: 10.2174/157018007780077444

Increase in Pharmacological Activity of Drugs in their Clathrates with Plant Glycosides

Volume:4   Issue:3
Pp: 168-170
T. G. Tolstikova, A. O. Bryzgalov, I. V. Sorokina, M. V. Hvostov, A. S. Ratushnyak, T. A. Zapara and O. G. Simonova
DOI: 10.2174/157018007780077453

Synthesis and Preliminary Biological Evaluation of Estrone Dimers

Volume:4   Issue:3
Pp: 171-174
Daniel Rabouina, Valerie Perrona, Blaise N'Zemba, Atul Guptaa, Rene-C. Gaudreault and Gervais Berube
DOI: 10.2174/157018007780077354

Design, Synthesis and Photodynamic Antimicrobial Activity of Ruthenium Trischelate Diimine Complexes

Volume:4   Issue:3
Pp: 175-179
R. F. Donnelly, N. C. Fletcher, P. J. McCague, J. Donnelly, P. A. McCarron and M. M. Tunney
DOI: 10.2174/157018007780077390

Novel, Acidic CCR2 Receptor Antagonists: From Hit to Lead

Volume:4   Issue:3
Pp: 185-191
D. Zou, H.-X. Zhai, J. Eckman, P. Higgins, M. Gillard, L. Knerr, S. Carre, P. Pasau, P. Collart and J. Grassi
DOI: 10.2174/157018007780077381

Rapid Classification of CYP3A4 Inhibition Potential Using Support Vector Machine Approach

Volume:4   Issue:3
Pp: 192-200
Diansong Zhou, Ruifeng Liu, Sara A. Otmani, Scott W. Grimm, Randy J. Zauhar and Ismael Zamora
DOI: 10.2174/157018007780077462

Synthesis and Antitumor Activity of Novel Pentacyclic Triterpenoid Lantadene D

Volume:4   Issue:3
Pp: 201-206
Manu Sharma, Pritam Dev Sharma, Mohinder Pal Bansal and Jaswant Singh
DOI: 10.2174/157018007780077471

A New 1,2,4-Triazole Acyclonucleosides: Synthesis and Biological Evaluation

Volume:4   Issue:3
Pp: 212-214
Smaail Radi and Hassan B. Lazrek
DOI: 10.2174/157018007780077372

Maximizing the Identification of Leads from Compound Mixtures

Volume:4   Issue:3
Pp: 215-223
Usha Warrior, Sujatha M. Gopalakrishnan, Linda Traphagen, Gail Freiberg, Danli Towne, Patrick Humphrey, James Kofron and David J. Burns
DOI: 10.2174/157018007780077408

mTOR Inhibition in Lymphoma: A Rational and Promising Strategy

Volume:4   Issue:3
Pp: 224-231
Sonali M. Smith and Koen van Besien
DOI: 10.2174/157018007780077435

Synthesis and Binding Properties of New Endothelin Receptor Ligands

Volume:4   Issue:3
Pp: 232-238
Maria Modica, Loredana Salerno, Valeria Pittala, Giuseppe Romeo, Mariangela Siracusa, Ilario Mereghetti, Alfredo Cagnotto and Tiziana Mennini
DOI: 10.2174/157018007780077426