Letters in Drug Design & Discovery

Editor-in-Chief
K. Kuca
University of Hradec Kralove
Hradec Kralove
Czech Republic

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Volume:2   Issue: 6
Pp: iv-iv

DOI: 10.2174/15701808105020600iv

Thermodynamic Aspects of Cancer: Possible Role of Negative Entropy in Tumor Growth, its Relation to Kinetic and Genetic Resistance

Volume:2   Issue: 6
Pp: 429-438
Joseph Molnar, Barry S. Thornton, Annamaria Molnar, Dezso Gaal, Liaofu Luo and Elke S. Bergmann-Leitner
DOI: 10.2174/1570180054771473

Discovery, Structural Determination and Anticancer Activities of Lactucinlike Guaianolides

Volume:2   Issue: 6
Pp: 444-450
Yulin Ren, Yawei Zhou, Xiaozhuo Chen and Yunhua Ye
DOI: 10.2174/1570180054771581

Phenyldihydroxypyrimidines as HCV NS5B RNA Dependent RNA Polymerase Inhibitors. Part I: Amides and Ureas

Volume:2   Issue: 6
Pp: 451-455
B. Crescenzi, M. Poma, J. M. Ontoria, A. Marchetti, E. Nizi, V. G. Matassa and C. Gardelli
DOI: 10.2174/1570180054771491

Phenyldihydroxypyrimidines as HCV NS5B RNA Dependent RNA Polymerase Inhibitors. Part II: Sulfonamides

Volume:2   Issue: 6
Pp: 456-461
S. Ponzi, C. Giuliano, M. Donghi, M. Poma, V. G. Matassa and I. Stansfield
DOI: 10.2174/1570180054771527

Micro Arrayed Compound Screening (μARCS) for Inhibitors of Methionine Aminopeptidase Type 2

Volume:2   Issue: 6
Pp: 462-469
Yihong Fan, Jieyi Wang, Pingping Lou, Jack Henkin, James L. Kofron, David J. Burns, Usha Warrior and Steven N Anderson
DOI: 10.2174/1570180054771518

Antiretroviral Therapy: Is it the Right Time for New Strategies?

Volume:2   Issue: 6
Pp: 470-474
N. Abrescia, M. D'Abbraccio, A. Busto, A. Maddaloni, M. Figoni and M. De Marco
DOI: 10.2174/1570180054771536

Selection of a Catalytically Active Enzyme In Vivo Via Phage Display of its Product

Volume:2   Issue: 6
Pp: 475-478
T. Taki, S. Fujita and K. Taira
DOI: 10.2174/1570180054771482

Redox Active Iron at the Center of Oxidative Stress in Alzheimer Disease

Volume:2   Issue: 6
Pp: 479-482
Kazuhiro Honda, Paula I. Moreira, Quan Liu, Sandra L. Siedlak, Xiongwei Zhu, Mark A Smith and George Perry
DOI: 10.2174/1570180054771545

Identifying Protein Binding Sites and Optimal Ligands

Volume:2   Issue: 6
Pp: 483-489
Albert Beuscher, Arthur J. Olson and David S. Goodsell
DOI: 10.2174/1570180054771572

Immunomodulatory Properties of Synthetic Imidazolone Derivatives

Volume:2   Issue: 6
Pp: 490-496
M. A. Mesaik, K. M. Khan, S. Rahat, Zia-Ullah Zia-Ullah, M. I. Choudhary, S. Murad, N. R. Abdullah, Atta-ur-Rahman Atta-ur-Rahman, A. Ahmad and R. A. Siddiqui
DOI: 10.2174/1570180054771554