Letters in Drug Design & Discovery

Editor-in-Chief:

George Perry
University of Texas
San Antonio, TX
USA

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Volume:2   Issue:2
Pp: v-v

DOI: 10.2174/157018081050202000v

Mitotic Checkpoint: A Therapeutic Target in the Treatment of Human Cancer

Volume:2   Issue:2
Pp: 97-104
Xianghong Wang, Y. C. Wong and Dong-Yan Jin
DOI: 10.2174/1570180053175098

The Role of an Amphiphilic Capping Group in Covalent and Non-Covalent Dipeptide Inhibitors of HCV NS3 Serine Protease

Volume:2   Issue:2
Pp: 113-117
Stefania Colarusso, Benjamin Gerlach, Claudio Giuliano, Uwe Koch, Victor G. Matassa and Frank Narjes
DOI: 10.2174/1570180053175089

P1 and P1; Optimization of [3,4]-Bicycloproline P2 Incorporated Tetrapeptidyl α-Ketoamide Based HCV Protease Inhibitors

Volume:2   Issue:2
Pp: 118-123
Shu-Hui Chen, Jason Lamar, Yvonne Yip, Frantz Victor, Robert B. Johnson, Q. May Wang, John I. Glass, Beverly Heinz, Joseph Colacino, Deqi Guo, Mark Tebbe and John E. Munroe
DOI: 10.2174/1570180053175115

Avidin Fusion Protein Strategies in Targeted Drug and Gene Delivery

Volume:2   Issue:2
Pp: 124-132
Olli H. Laitinen, Kari J. Airenne, Jani K. Raty, Thomas Wirth and Seppo Yla-Herttuala
DOI: 10.2174/1570180053175197

Synthesis and In Vitro Evaluation of Adenosine Deaminase Resistant N-6 Aminal and Thioaminal Prodrugs of Cordycepin

Volume:2   Issue:2
Pp: 133-136
Hui-Min Chang, Jesse Oakes, Anders Olsson, Luminita Panaitescu, B. Mark Britt, Christopher M. Kearney and Robert R. Kane
DOI: 10.2174/1570180053175151

Recognition of Specific DNA Sequences by Stacked Pyrrole- and Imidazole- Containing Polyamides: An Efficient Screening Method Based on Competitive Dialysis

Volume:2   Issue:2
Pp: 137-142
Karen L. Buchmueller, Sarah M. Horick, Cameron M. Howard, Peter B. Uthe, Andrew M. Staples, Suzanna L. Bailey, N. Minh Le, Kari K. Cox, James A. Henry and Moses Lee
DOI: 10.2174/1570180053175160

Neuroprotection in Huntington;s Disease

Volume:2   Issue:2
Pp: 143-147
Raphael M. Bonelli, Anna K. Hodl and Hans-Peter Kapfhammer
DOI: 10.2174/1570180053175133

Biodegradable Additives Modulate Ganciclovir Release Rate From PLGA Microspheres Destined to Intraocular Administration

Volume:2   Issue:2
Pp: 148-149
Emilia Barcia, Cristina Herradon and Rocío Herrero-Vanrell
DOI: 10.2174/1570180053175188

Activity of Amidine-containing Diphenylureas Against P. falciparum

Volume:2   Issue:2
Pp: 162-164
Guatam Bhattacharya, Lucia Gerena, Suping Jiang and Karl A. Werbovetz
DOI: 10.2174/1570180053175061

Tamarind Inhibits Solar-Simulated Ultraviolet Radiation-Induced Suppression of Recall Responses in Humans

Volume:2   Issue:2
Pp: 165-171
J. M. Kuchel, R. St. C. Barnetson, L. Zhuang, F. M. Strickland, R. P. Pelley and G. M. Halliday
DOI: 10.2174/1570180053175106