Letters in Drug Design & Discovery

Editor-in-Chief
K. Kuca
University of Hradec Kralove
Hradec Kralove
Czech Republic

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Volume:16   Issue: 7
Pp: 711-711
Bernard Pirotte
DOI: 10.2174/157018081607190603094001



Synthesis, Characterization, Free-radical Scavenging Capacity and Antioxidant Activity of Novel Series of Hydrazone, 1,3,4-oxadiazole and 1,2,4- triazole Derived from 3,5-dimethyl-1H-pyrazole

Volume:16   Issue: 7
Pp: 712-720
Khalid Karrouchi*, Saad Fettach, Smaail Radi*, El bekkaye Yousfi, Jamal Taoufik, Yahia Nasser Mabkhot, Seham Alterary, My El Abbes Faouzi and Muhammed Ansar
DOI: 10.2174/1570180815666180516103050



Design and Synthesis of Benzopyranopyrimidinyl Phosphonates as Cytotoxic and Antioxidant Agents

Volume:16   Issue: 7
Pp: 721-733
Sarva Santhisudha, Gundluru Mohan, Tenkayala Sobha Rani, Peddaiahgari Vasu Govardhana Reddy and Cirandur Suresh Reddy*
DOI: 10.2174/1570180815666180606083418



Synthesis, Anti-inflammatory, Antimicrobial Potential and Molecular Docking Studies of 4,5-Disubstituted-1,2,4-Triazole Thioacetate Derivatives

Volume:16   Issue: 7
Pp: 734-745
Muhammad Nouman Arif, Humaira Nadeem*, Rehan Zafar Paracha, Arif-ullah Khan, Muhammad Imran and Fawad Ali
DOI: 10.2174/1570180815666180810122226



QSAR and Molecular Modeling Studies on a Series of Pyrrolidine Analogs Acting as BACE-1 Inhibitors

Volume:16   Issue: 7
Pp: 746-760
Richa Arya, Satya Prakash Gupta*, Sarvesh Paliwal, Seema Kesar, Achal Mishra and Yenamandra Subrahmanya Prabhakar
DOI: 10.2174/1570180815666180627124422



Structure Based Identification of Potential Inhibitors of NS3 Protein of Zika Virus

Volume:16   Issue: 7
Pp: 761-774
Md. Imam Faizan, Abu Turab Naqvi , Md. Imtaiyaz Hassan, Mohd. Abdullah, Ayesha Tazeen, Zoya Shafat, Malik Hisamuddin, Aftab Alam, Shahnawaz Ali, Sher Ali, Anam Farooqui, Abu Hamza, Nazish Parveen, Farah Deeba, Anwar Ahmed and Shama Parveen*
DOI: 10.2174/1570180815666180821105012



Novel Trifluoromethylpyrazole Acyl Thiourea Derivatives: Synthesis, Antifungal Activity and Docking Study

Volume:16   Issue: 7
Pp: 785-791
Han Wang, Zhi-Wen Zhai, Yan-Xia Shi, Cheng-Xia Tan, Jian-Quan Weng, Liang Han, Bao-Ju Li and Xing-Hai Liu*
DOI: 10.2174/1570180815666180704103047



Design, Synthesis and Anti-tuberculosis Activity of Hydrazones and N-acylhydrazones Containing Vitamin B6 and Different Heteroaromatic Nucleus

Volume:16   Issue: 7
Pp: 792-798
Thais Cristina Mendonça Nogueira, Lucas dos Santos Cruz, Maria Cristina Lourenço and Marcus Vinicius Nora de Souza*
DOI: 10.2174/1570180815666180627122055



Design, Synthesis and Cytotoxicity of Novel Coumarin-1,2,3-triazole-1,2,4- Oxadiazole Hybrids as Potent Anti-breast Cancer Agents

Volume:16   Issue: 7
Pp: 818-824
Maryam Mohammadi-Khanaposhtani, Kiana Fahimi, Elahe Karimpour-Razkenari, Maliheh Safavi, Mohammad Mahdavi, Mina Saeedi and Tahmineh Akbarzadeh*
DOI: 10.2174/1570180815666180627121006