Letters in Drug Design & Discovery

Editor-in-Chief
K. Kuca
University of Hradec Kralove
Hradec Kralove
Czech Republic

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Volume:16   Issue: 6
Pp: 607-607
Dimitra Hadjipavlou-Litina
DOI: 10.2174/157018081606190503093903



Virtual Screening, Docking, Synthesis and Bioactivity Evaluation of Thiazolidinediones as Potential PPARγ Partial Agonists for Preparation of Antidiabetic Agents

Volume:16   Issue: 6
Pp: 608-617
Beina Zhang, Mao Shu*, Chunmei Xu, Chunhong An, Rui Wang and Zhihua Lin*
DOI: 10.2174/1570180815666180827123512




Design, Synthesis and Evaluation of Thiourea Derivatives as Antimicrobial and Antiviral Agents

Volume:16   Issue: 6
Pp: 618-624
Veerasamy Ravichandran*, Sivadasan Shalini, Krishnan Suresh Kumar, Harish Rajak and Ram Kishore Agrawal
DOI: 10.2174/1570180815666180801120440




Virtual Screening of Henna Compounds Library for Discovery of New Leads against Human Thymidine Phosphorylase, an Overexpressed Factor of Hand-Foot Syndrome

Volume:16   Issue: 6
Pp: 625-636
Davood Khodabakhshi-Javinani, Azadeh Ebrahim-Habibi*, Minoo Afshar and Latifeh Navidpour*
DOI: 10.2174/1570180815666180816123233




New Procaspase Activating Compound (PAC-1) Like Molecules as Potent Antitumoral Agents Against Lung Cancer

Volume:16   Issue: 6
Pp: 645-655
Leyla Yurttaş*, Ömer Öztürk and Zerrin Cantürk
DOI: 10.2174/1570180815666180926113040




Novel 1,3,4-Oxadiazole Fused Thiadiazole Derivatives: Synthesis and study of Anticancer Activities

Volume:16   Issue: 6
Pp: 656-662
Zanjam Spandana, Reddymasu Sreenivasulu, Tadigiri MalathiRekha and Mandava Venkata Basaveswara Rao*
DOI: 10.2174/1570180816666181031125946




Synthesis and Anti-Tumor Activity Evaluation of Novel 7-Fluoro-4-(1- Piperazinyl) Quinolines

Volume:16   Issue: 6
Pp: 663-669
Dan Liu*, Aiqi Xue, Zhixin Liu, Yi Zhang, Penghui Peng and Haifeng Wang
DOI: 10.2174/1570180815666180820131036




Exploring Energy Profiles of Protein-Protein Interactions (PPIs) Using DFT Method

Volume:16   Issue: 6
Pp: 670-677
Sanket Bapat, Renu Vyas* and Muthukumarasamy Karthikeyan
DOI: 10.2174/1570180815666180815151141




Design and Synthesis of the Diazirine-based Clickable Photo-affinity Probe Targeting Sphingomyelin Synthase 2 open access plus

Volume:16   Issue: 6
Pp: 678-684
Penghui Wang, Zhining Li, Lulu Jiang, Lu Zhou* and Deyong Ye*
DOI: 10.2174/1570180816666181106154601




Synthesis, Formulation and Analytical Method Validation of Rutin Derivative

Volume:16   Issue: 6
Pp: 685-695
Murad Abualhasan*, Mohyeddin Assali, Nidal Jaradat and Tala Sarhan
DOI: 10.2174/1570180816666181108114706




Action of Thioglycosides of 1,2,4-Triazoles and Imidazoles on the Oxidative Stress and Glycosidases in Mice with Molecular Docking

Volume:16   Issue: 6
Pp: 696-710
Mahmoud Balbaa*, Doaa Awad, Ahmad Abd Elaal, Shimaa Mahsoub, Mayssaa Moharram, Omayma Sadek, Nadjet Rezki, Mohamed Reda Aouad, Mohamed El-Taher Ibrahim Badawy and El Sayed Helmy El Ashry
DOI: 10.2174/1573413715666181212150955