Letters in Drug Design & Discovery

Editor-in-Chief
K. Kuca
University of Hradec Kralove
Hradec Kralove
Czech Republic

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Volume:15   Issue: 7
Pp: 699-699
Matthias Tacke
DOI: 10.2174/157018081507180530115353



Synthesis and in vitro Evaluation of 1,2,3-triazole-4-chloromethylcoumarins with Antioxidant Activity

Volume:15   Issue: 7
Pp: 700-705
Anna Carolina Schneider Alves, Thais Munhoz, Fabiana Gomes Nascimento Soares, Liliana Rockenbach, Bruna Gauer, Daniel Fabio Kawano, Gilsane Lino von Poser, Solange Cristina Garcia and Vera Lucia Eifler-Lima*
DOI: 10.2174/1570180814666171011165051



Efficient Synthesis of Ibandronate in the Presence of an Ionic Liquid open access plus

Volume:15   Issue: 7
Pp: 713-720
David Illes Nagy, Alajos Grun, Oliver Pavela, Sandor Garadnay, Istvan Greiner and Gyorgy Keglevich*
DOI: 10.2174/1570180814666171027160324



3D QSAR Studies of Tricyclic Compounds as Porcupine Inhibitors for Wnt Pathway Inhibitory Activity

Volume:15   Issue: 7
Pp: 721-732
Liqiang Meng, Liqian Sun, Chaoqun Yan, Dongxiao Cui, Jingrun Chen, Taigang Liang* and Qingshan Li*
DOI: 10.2174/1570180814666171002162025



Synthesis of New Thiazolyl-Pyrazoline Derivatives and Evaluation of Their Antimicrobial, Cytotoxic and Genotoxic Effects

Volume:15   Issue: 7
Pp: 744-756
Belgin Sever, Mehlika Dilek Altıntop, Hulya Karaca Gencer, Handan Acelya Kapkac, Ozlem Atli, Merve Baysal and Ahmet Ozdemir*
DOI: 10.2174/1570180814666170925152902



Novel Hybrid Molecules of Quinazoline Chalcone Derivatives: Synthesis and Study of in vitro Cytotoxic Activities

Volume:15   Issue: 7
Pp: 757-765
Arunkumar Thiriveedhi*, Ratnakaram Venkata Nadh, Navuluri Srinivasu and Kishore Kaushal
DOI: 10.2174/1570180814666171013162148



Synthesis, Aqueous Solubility, Metabolic Stability and Pharmacological Profile of Simplified Urea Derivatives

Volume:15   Issue: 7
Pp: 766-777
Raquel de Oliveira Lopes, Marina Amaral Alves, Roberta Olmo Pinheiro, Cristina Setim Freitas, Fernando Q. Cunha, Eliezer J. Barreiro* and Lídia Moreira Lima*
DOI: 10.2174/1570180814666171012155204



Synthesis, Pharmacological Evaluation and Docking Study of a New Modulator of Microtubule Polymerization

Volume:15   Issue: 7
Pp: 778-786
Teiliane R. Carneiro, Daniel N. do Amaral, Harold H. Fokoue, Carlos M.R. Sant`Anna, Maria L.G. Porras, Augusto C.A. Oliveira, Bruno C. Cavalcanti, Claudia Pessoa, Eliezer J. Barreiro and Lidia M. Lima*
DOI: 10.2174/1570180814666171012162557



Enhancement Antimicrobial Activity of Clarithromycin by Amine Functionalized Mesoporous Silica Nanoparticles as Drug Delivery System

Volume:15   Issue: 7
Pp: 787-795
Pegah Khosravian, Mehdi Khoobi, Mehdi Shafiee Ardestani, Mohammad Porgham Daryasari, Malihe Hassanzadeh, Payam Ghasemi-Dehkordi, Massoud Amanlou and Hamid Akbari Javar*
DOI: 10.2174/1570180815666180117155818



Review of Medicinal Plants and their Compounds for Aldose Reductase Inhibitory Activity

Volume:15   Issue: 7
Pp: 796-812
Saliha Bouknana, Mohamed Bouhrim, Hayat Ouassou and Mohamed Bnouham*
DOI: 10.2174/1570180814666171011163954