Letters in Drug Design & Discovery

Editor-in-Chief
K. Kuca
University of Hradec Kralove
Hradec Kralove
Czech Republic

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N-(2-(Arylmethylimino)Ethyl)-7-Chloroquinolin-4-Amine Derivatives: A New and Potent Class of Anticancer Agents

Volume:15   Issue: 2
Pp: 113-117
Ligia S. da Silveira Pinto, Marcus V.N. de Souza*, Carlos R. Kaiser, James L. Wardell and Solange M.S.V. Wardell
DOI: 10.2174/1570180814666170512123720




Synthesis and Antioxidant Evaluation of a New Class of Thienopyrimidine-rhodanine Hybrids

Volume:15   Issue: 2
Pp: 118-126
Kerru Nagaraju , Venkata H.S.S. Bhaskaruni, Ravada Kishore , Suresh Maddila*, Parvesh Singh and Sreekantha B. Jonnalagadda
DOI: 10.2174/1570180814666170710161844




α-Glucosidase Inhibition, Antioxidant and Docking Studies of Hydroxycoumarins and their Mono and Bis O-alkylated/acetylated Analogs

Volume:15   Issue: 2
Pp: 127-135
Parvesh Singh*, Nomandla Ngcoya, Ramgopal Mopuri, Nagaraju Kerru, Neha Manhas, Oluwakemi Ebenezer and Md. Shahidul Islam
DOI: 10.2174/1570180814666170602081941




High Throughput Screening and Molecular Docking of Calmodulin with Antagonists of Trifluoperazine and Phenothiazine Chemical Class

Volume:15   Issue: 2
Pp: 136-142
Abdelmonem Messaoudi*, Zarrin Basharat and Asif Naqvi
DOI: 10.2174/1570180814666170602081412




Development of Structure Activity Correlation Model on Aroylindole Derivatives as Anticancer Agents

Volume:15   Issue: 2
Pp: 143-153
Vijay K. Patel and Harish Rajak*
DOI: 10.2174/1570180814666170823161751




Synthesis and Antimicrobial Activity of Some New N-(1H-benzimidazol-2- yl)-2-mercaptoacetamide Derivatives

Volume:15   Issue: 2
Pp: 154-159
Asaf Evrim Evren, Sinem Tekinkoca and Leyla Yurttas*
DOI: 10.2174/1570180814666170619092147




Pd/C-catalyzed Synthesis of 4-biaryl Substituted 2-amino benzo[h] chromene Derivatives as Potential Cytotoxic Agents

Volume:15   Issue: 2
Pp: 160-168
Chekuri Sharmila Rani, Meda Haritha, Mandava V. Basaveswara Rao* and Manojit Pal*
DOI: 10.2174/1570180814666170530094023




QSAR and Molecular Docking Studies on a Series of 1-Amino-5H-pyrido [4, 3-b]indol-4-carboxamides Acting as Janus Kinase 2 (JAK2) Inhibitors

Volume:15   Issue: 2
Pp: 169-180
Basheerulla Shaik*, Satya P. Gupta, Tabassum Zafar and K. Anita
DOI: 10.2174/1570180814666170605113844




Synthesis of New Heteroaryl Substituted Morpholine Tagged Triazines and Evaluation of their Cytotoxic Activity

Volume:15   Issue: 2
Pp: 181-192
Sivaprasad Kasturi, Sujatha Surarapu, Srinivas Uppalanchi, Hasitha Shilpa Anantaraju, Shubham Dwivedi, Perumal Yogeeswari, Krishna S. Ethiraj and Jaya Shree Anireddy*
DOI: 10.2174/1570180814666170605115335




Synthesis and Biological Evaluation of New Quinoline-Based Thiazolyl Hydrazone Derivatives as Potent Antifungal and Anticancer Agents

Volume:15   Issue: 2
Pp: 193-202
Ali Erguc, Mehlika Dilek Altintop*, Ozlem Atli, Belgin Sever, Gokalp Iscan, Gozde Gormus and Ahmet Ozdemir
DOI: 10.2174/1570180814666171003145227




The Effectiveness of Different Treatment Modalities for the Management of Ocular Injuries Following Sulfur Mustard Exposure

Volume:15   Issue: 2
Pp: 203-211
Yunes Panahi, Mostafa Naderi, Shahbaz Nekoozadeh, Seyyed Mahdi Rajaee and Amirhossein Sahebkar*
DOI: 10.2174/1570180814666170607145714