Letters in Drug Design & Discovery

Editor-in-Chief
K. Kuca
University of Hradec Kralove
Hradec Kralove
Czech Republic

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Volume:15   Issue: 10
Pp: 1019-1019
Ahmed Kamal
DOI: 10.2174/157018081510180827103546



Synthesis and Cytotoxicity Evaluation of Novel Tricyclic Dihydropyrazolo [4,3-f][1,2,3]triazolo Diazepines

Volume:15   Issue: 10
Pp: 1020-1025
Chiranjeevi Bingi, Ashok Kale, Yedla Poornachandra, Chityal Ganesh Kumar and Krishnaiah Atmakur*
DOI: 10.2174/1570180815666180222143229




Biological Activities and Docking Studies on Novel Bis 1,4-DHPS Linked to Arene Core via Ether or Ester Linkage

Volume:15   Issue: 10
Pp: 1036-1045
Nada S. Ibrahim, Magda F. Mohamed, Ahmed H. M. Elwahy* and Ismail A. Abdelhamid*
DOI: 10.2174/1570180815666180105162323




3D-QSAR Studies on New Benzothiazole-Based Dual Functional Inhibitors of BCR-ABL Kinase Including the T315I Mutant

Volume:15   Issue: 10
Pp: 1046-1056
Shunlai Li, Chaorui Ren, Chenghu Lu, Xiuxiu Li and Hongguang Du*
DOI: 10.2174/1570180815666180105163053




Antimicrobial Activities of Synthetic Arylidine Nicotinic and Isonicotinic Hydrazones

Volume:15   Issue: 10
Pp: 1057-1067
Muhammad Hayat, Khalid Mohammed Khan*, Sumayya Saeed, Uzma Salar, Momin Khan, Taimoor Baig, Aqeel Ahmad, Shahnaz Parveen and Muhammad Taha
DOI: 10.2174/1570180814666170914120337




Unveiling the Accuracy of Homology Modeling to Elucidate the Structure of GPCRs-HIV Co-receptor-CCR5 as a Case Study

Volume:15   Issue: 10
Pp: 1068-1078
Vadivelu Aanand, Rajendran Anitha, Somarathinam Kanagasabai, Gunalan Seshan, Changdev G. Gadhe and Gugan Kothandan*
DOI: 10.2174/1570180814666171120153956




In Vitro Antibacterial and Antifungal Activity and Computational Evaluation of Novel Indole Derivatives Containing 4-Substituted Piperazine Moieties

Volume:15   Issue: 10
Pp: 1079-1086
Tunca Gul Altuntas*, Nilufer Yilmaz, Abdulilah Ece, Nurten Altanlar and Sureyya Olgen
DOI: 10.2174/1570180815666180109161948




Synthesis and Antibacterial/Antitubercular/Antioxidant Activities of Compounds Containing Fluoroquinolone Ring Linked to a 4-thiazolidinone Moiety

Volume:15   Issue: 10
Pp: 1087-1094
Tejeswara Rao Allaka, Naresh Kumar Katari, Venkanna Banothu, Srinubabu Maddela, Manojit Pal* and Jaya Shree Anireddy*
DOI: 10.2174/1570180815666171229150032




2-Amino Analogues of Alkynyl Substituted 1,4-dihydropyrimidine: Their Synthesis and Evaluation as Potential Antimicrobial/Cytotoxic Agents

Volume:15   Issue: 10
Pp: 1095-1102
V. Mallikarjuna Rao, A. Srinivasa Rao*, P. Ravi Kumar, S. Shobha Rani and Manojit Pal*
DOI: 10.2174/1570180814666171121151921




Plant Antioxidants and Mechanisms of Action

Volume:15   Issue: 10
Pp: 1103-1115
Weslley Felix de Oliveira, Priscila Marcelino dos Santos Silva, Luana Cassandra Breitenbach Barroso Coelho* and Maria Tereza dos Santos Correia*
DOI: 10.2174/1570180815666180222142521




Synthesis and Cytotoxic Activity of 2,6-Diarylidenecyclohexanones and their 6-Amino-1,3-dimethyluracil Monoadducts

Volume:15   Issue: 10
Pp: 1116-1122
Erika Madeleyne Ramos-Rivera, Cuauhtemoc Alvarado, Jose D. Solano, Luis Roa de la Fuente, Angeles Dominguez-Rivera, Miguel Angel Vilchis-Reyes* and Miguel Angel Martinez-Urbina*
DOI: 10.2174/1570180815666180105164032