Letters in Drug Design & Discovery

Editor-in-Chief
K. Kuca
University of Hradec Kralove
Hradec Kralove
Czech Republic

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Volume:14   Issue: 8
Pp: 861-861
John F. Honek*
DOI: 10.2174/157018081408170720180649



A Two QSAR Way for Antidiabetic Agents Targeting Using α-Amylase and α-Glucosidase Inhibitors: Model Parameters Settings in Artificial Intelligence Techniques

Volume:14   Issue: 8
Pp: 862-868
Karel Dieguez-Santana*, Hai Pham-The, Oscar M. Rivera-Borroto, Amilkar Puris, Huong Le-Thi-Thu and Gerardo M. Casanola-Martin*
DOI: 10.2174/1570180814666161128121142



Copper Complexes of 8-Aminoquinoline and Uracils as Novel Aromatase Inhibitors

Volume:14   Issue: 8
Pp: 880-884
Nujarin Sinthupoom, Veda Prachayasittikul, Ratchanok Pingaew, Apilak Worachartcheewan, Supaluk Prachayasittikul*, Somsak Ruchirawat and Virapong Prachayasittikul*
DOI: 10.2174/1570180813666161103144822



3,4-Dihydropyrimidin-2(1H)-one C5 Amides as Inhibitors of T NFα Production: Synthesis, Biological Evaluation and Molecular Modeling

Volume:14   Issue: 8
Pp: 885-897
Ahmad Ebadi, Mehdi Khoshneviszadeh, Katayoun Javidnia, Mohammad Hossein Ghahremani, Omidreza Firuzi* and Ramin Miri*
DOI: 10.2174/1570180814666170306120235



Acetaminophen (Paracetamol) Facilitated Extinction Lear ning in Contextual Fear Conditioned Rats

Volume:14   Issue: 8
Pp: 898-903
Neelam Zaman, Hammad Ahmad, Mobasher Ali Abid, Nisar-ur-Rahman, Talat Roome and Ghulam Abbas*
DOI: 10.2174/1570180814666170203162557



Synthesis, Anti-inflammatory and Molecular Docking Study of Schiff Bases Containing Methanesulphonyl Pharmacophore

Volume:14   Issue: 8
Pp: 930-937
Khaled R. A. Abdellatif*, Mohammed T. Elsaady, Salah A. Abdel-Aziz and Ahmed H. A. Abu Sabah
DOI: 10.2174/1570180814666161214163759



Molecular Docking and Structure Activity Relationship Studies of NSAIDs. What do they Reveal about IC50?

Volume:14   Issue: 8
Pp: 949-958
Chrysoula Mikra, Georgios Rossos, Sotirios K. Hadjikakou and Nikolaos Kourkoumelis*
DOI: 10.2174/1570180814666161207143231



Molecular Docking, 3D-QSAR and Structural Optimization of Indole Biphenylcarboxylic Acids as PPARγ Antagonists

Volume:14   Issue: 8
Pp: 959-973
Xin Liu, Yu-Ze Zhang, Zhi Jing, Wen-Qing Jia, Shu-Qing Wang, Wei-Ren Xu and Xian-Chao Cheng*
DOI: 10.2174/1570180814666161207130047