Letters in Drug Design & Discovery

Editor-in-Chief
K. Kuca
University of Hradec Kralove
Hradec Kralove
Czech Republic

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Volume:14   Issue: 7
Pp: 751-751
Kamil Kuca*
DOI: 10.2174/157018081407170630181923



A Facile Synthesis and Drug Design of Some New Heterocyclic Compounds Incorporating Pyridine Moiety and Their Antimicrobial Evaluation

Volume:14   Issue: 7
Pp: 752-762
Fathy M. Abdelrazek, Sobhi M. Gomha*, Aly H. Abdelrahman, Peter Metz and Mohsen A. Sayed
DOI: 10.2174/1570180814666161128120240



Novel Chromeno[2,3-d]pyrimidines-Design, Synthesis and Antioxidant Activity

Volume:14   Issue: 7
Pp: 763-772
Kotiah Yalagala, Sreekantha B. Jonnalagadda*, Suresh Maddila, Surjyakanta Rana and Surya Narayana Maddila
DOI: 10.2174/1570180814666161123143637



Design, Synthesis, Antioxidant and Anticancer Activity of New Coumarin Derivatives Linked with Thiazole, Isoxazole or Pyrazole Moiety

Volume:14   Issue: 7
Pp: 773-781
Khaled R. A. Abdellatif*, Mohamed A. Abdelgawad, Heba A. H. Elshemy, Nesma M. Kahk and Dalia M. El Amir
DOI: 10.2174/1570180813666161026153743



In vitro and In silico Analysis of β-lactam Derivatives as Antimycobacterial Agents

Volume:14   Issue: 7
Pp: 782-786
Julieta Luna-Herrera, Edgar E. Lara-Ramirez, Ana R. Munoz-Duarte, Fabian E. Olazaran, Manuel J. Chan-Bacab, Rosa Moo-Puc, Alondra M. Perez-Vazquez, Cynthia M. Morales-Reyes and Gildardo Rivera*
DOI: 10.2174/1570180814666170106111316



Synthesis, Enzyme Assays and Molecular Docking Studies of Fluorina ted Bioisosteres of Santacruzamate A as Potential HDAC Tracers

Volume:14   Issue: 7
Pp: 787-797
Muneer Ahamed, Koen Vermeulen, Michael Schnekenburger, Lise Roman Moltzau, Finn Olav Levy, Janos Marton, Mathy Froeyen, Dag Erlend Olberg, Marc Diederich and Guy Bormans
DOI: 10.2174/1570180813666161101152943



3D-QSAR Studies of HDAC6 Inhibitors Using Docking-Based Alignment

Volume:14   Issue: 7
Pp: 798-810
Chunqi Hu, Liang Hong, Jun Li and Wenting Du*
DOI: 10.2174/1570180813666161028165151



Inhibition of Product Template (PT) Domain of Aflatoxin Producing Polyketide Synthase Enzyme of Aspergillus parasiticus

Volume:14   Issue: 7
Pp: 811-818
Maneesh Kumar, Sindhuprava Rana, Harish Kumar, Jainendra Kumar, Rani Mansuri and Ganesh Chandra Sahoo*
DOI: 10.2174/1570180814666170203144914



Tranylcypromine Attenuates Senescence in Dental Pulp Stem Cells

Volume:14   Issue: 7
Pp: 819-826
Junjun Liu, Zhi Liu, Chunyan Wang, Fang Yu, Wenping Cai, Xi Lu, Rongbin Wei, Shouliang Zhao, Yumei Zhao* and Shangfeng Liu*
DOI: 10.2174/1570180814666161229165048



Nano Conjugated PLGA-Chlorambucil: Synthesis In Vitro Anti Non- Hodgkin's Lymphoma Cellular Assay

Volume:14   Issue: 7
Pp: 827-836
Saeed Akbarian, Jafar Sojoodi, Fatemeh Monnavari, Hossein Heidari, Pegah Khosravian, Hamid A. Javar, Artin Assadi, Rahimeh Rasouli, Mostafa Saffari, Seyed A.S. Shandiz, Hadi Hejazinia, Farnoor D. Omoomi, Mohammad Saffari and Mehdi S. Ardestani*
DOI: 10.2174/1570180814666161130113446



Extended-release Formulation Attenuates the Impacts of Fluvastatin on Serum PCSK9 Levels in Humans

Volume:14   Issue: 7
Pp: 837-842
Yuan-Lin Guo, Wei Zhang, Qian Dong, Geng Liu, Cheng-Gang Zhu, Jing Sun, Rui-Xia Xu and Jian-Jun Li*
DOI: 10.2174/1570180814666161216121558



Polyphenolic Compound from Vitis vinifera L. have Potential for the Alzheimer Disease Treatment

Volume:14   Issue: 7
Pp: 853-859
Soukup Ondrej, Stralkova Radomira, Mistova Tereza, Popov Marek, Hejtmankova Alena, Lachman Jaromir, Klimova Blanka and Kuca Kamil*
DOI: 10.2174/1570180814666161116112300