Letters in Drug Design & Discovery

Editor-in-Chief:

George Perry
University of Texas
San Antonio, TX
USA

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Volume:14   Issue:3
Pp: 251-251
George Perry
DOI: 10.2174/157018081403170126205345



Design, Synthesis and Evaluation of Novel Derivatives of Orotic Acid Amide as Potent Glucokinase Activators

Volume:14   Issue:3
Pp: 252-261
Leilei Zhang, Shengquan Hu, Lei Lei, Yuliang Zhang, Lijing Zhang, Hongrui Song, Zhufang Shen and Zhiqiang Feng
DOI: 10.2174/1570180813666161013150056



Design, Synthesis and Insecticidal Activity of Diamides with Oxydibenzene or Diphenylamine Subunits

Volume:14   Issue:3
Pp: 262-269
Ye Liu, Xinfei Chen, Xiaoyong Xu, Jiagao Cheng, Xusheng Shao and Zhong Li
DOI: 10.2174/1570180813666161028113852



3D-QSAR, Molecular Docking and Molecular Dynamics Studies of 2,4- Diarylaminopyrimidine Analogues (DAAP Analogues) as Potent ALK Inhibitors

Volume:14   Issue:3
Pp: 270-286
Fulong Wu, Qianqian Lv, Zhonghua Wang, Dandan Li, Peng Peng, Yan Yin, Siheng Cui and Fanhong Wu
DOI: 10.2174/1570180813666160930162831



Design, Synthesis and Biological Evaluation of Novel Tetrahydroquinoline Based Propanehydrazides as Antitubercular Agents

Volume:14   Issue:3
Pp: 293-300
Subhash Chander, Penta Ashok, Bidart de Macedo Maira, Paul Cos, Davie Cappoen and Sankaranarayanan Murugesan
DOI: 10.2174/1570180813666160622094013



3D-QSAR Studies of Novel Cytotoxic Bufadienolides via CoMFA and CoMSIA Approaches

Volume:14   Issue:3
Pp: 306-313
Hui Lin, Shengrong Li, Shiyao Li, Kangjia Liu, Yushui Han, Jialiang Guo, Longxin Lin, Yiqun Chang, Gaokeng Xiao, Weimin Chen and Pinghua Sun
DOI: 10.2174/1570180813666160906150621



Synthesis and Nematocidal Activity of Novel Pyrazole Carboxamide Derivatives Against Meloidogyne incognita

Volume:14   Issue:3
Pp: 323-329
Wen Zhao, Zhong-Hua Shen, Jia-Hua Xing, Tian-Ming Xu, Wei-Li Peng and Xing-Hai Liu
DOI: 10.2174/1570180813666160930164327



Structural Studies of Aminopeptidase P from Plasmodium falciparum: A Novel Target Against Malaria

Volume:14   Issue:3
Pp: 330-338
Polaboina Snigdha, Pachineella Lakshmana Rao, Nagu Prakash Prabhu and Insaf Ahmed Qureshi
DOI: 10.2174/1570180813666160725113524



Anti-biofilm and Antibacterial Effects of Novel Metal-coordinated Sulfamethoxazole Against Escherichia coli

Volume:14   Issue:3
Pp: 339-344
Caren Rigon Mizdal, Sílvio Terra Stefanello, Pauline Cordenonsi Bonez, Vanessa Albertina Agertt, Vanessa da Costa Flores, Grazielle Guidolin Rossi, Fallon dos Santos Siqueira, Lenice de Lourenco Marques and Marli Matiko Anraku de Campos
DOI: 10.2174/1570180813666160930101653



Novel Second Generation HIV Integrase Inhibitor-DOLUTEGRAVIR: An Emerging Weapon Against HIV

Volume:14   Issue:3
Pp: 354-371
Vivek Jain, Diksha Gupta, Ashutosh Pareek and Yashumati Ratan
DOI: 10.2174/1570180813666160909121751