Letters in Drug Design & Discovery

Editor-in-Chief
K. Kuca
University of Hradec Kralove
Hradec Kralove
Czech Republic

Back

Become EABM
Become Reviewer

Preface promotion: free to download

Volume:14   Issue: 1
Pp: 1-1
Atta-ur-Rahman
DOI: 10.2174/157018081401161129101739



Proteochemometrics for the Prediction of Binding to the MHC Proteins

Volume:14   Issue: 1
Pp: 2-9
Ventsislav Yordanov, Ivan Dimitrov and Irini Doytchinova
DOI: 10.2174/1570180813666160630122341



Relationships Between the Structural Properties of Flavonoids and their Inhibitory Activities Against Matrix Metallopeptidase 9

Volume:14   Issue: 1
Pp: 28-35
Soon Young Shin, Hyeryoung Jung, Yearam Jung, Beom Soo Kim, Young Han Lee and Yoongho Lim
DOI: 10.2174/1570180813666160919161434



3D-QSAR Modeling and Molecular Docking Study on Small Molecule Stat3 Inhibitors, Src Homology 2 Domain Binders

Volume:14   Issue: 1
Pp: 36-49
Jing Li Wang, Li Ping Cheng, Yang Ping Quan, Zhen Wang, Fan Hong Wu and Wei Deng
DOI: 10.2174/1570180813666160801152618



Synthesis and Biological Activity of Quinoxalone Derivatives as BRD4 Bromodomain Inhibitors

Volume:14   Issue: 1
Pp: 50-57
Bin Xu, Lei-Lei Zhao, Yi-Fei Yang, Jian Zhang, Ling-Yun Yang, Bing Zhang, Li Han, Hui-Bin Zhang and Jin-Pei Zhou
DOI: 10.2174/1570180813666160715160857



1,2,3-Triazole-Isoxazole Based Acetylcholinesterase Inhibitors: Synthesis, Biological Evaluation and Docking Study

Volume:14   Issue: 1
Pp: 58-65
Zahra Najafi, Mohammad Mahdavi, Mina Saeedi, Reyhaneh Sabourian, Mahnaz Khanavi, Maliheh Safavi, Maliheh Barazandeh Tehrani, Abbas Shafiee, Alireza Foroumadi and Tahmineh Akbarzadeh
DOI: 10.2174/1570180813666160628085515



Computational Identification of Inhibitors Against DPP-IV for Checking Type-2 Diabetes

Volume:14   Issue: 1
Pp: 66-73
Sarvesh Kumar Gupta, Kamal Kumar Chaudhary, Utkarsh Raj and Nidhi Mishra
DOI: 10.2174/1570180813666160720121718



Combined 3D-QSAR, Pharmacophore and Docking Studies on Benzenesulfonamide Derivatives as Potent 12-Lipoxygenase Inhibitors

Volume:14   Issue: 1
Pp: 74-82
Chunhong An, Mao Shu, Xiaoli Zai, Beina Zhang, Jing Li, Zichao Chang, Yong Hu and Zhihua Lin
DOI: 10.2174/1570180813666160930100456



Synthesis and Biological Evaluation of a Novel Apogossypolone Derivative

Volume:14   Issue: 1
Pp: 96-101
Yonghua Zhan, Xu Cao, Yingchao Li, Xueli Chen and Xiaofeng Huang
DOI: 10.2174/1570180813666160722115855



Novel Artemisinin-Derived Dimers: Synthesis and Evaluation of Anti-cancer Activities

Volume:14   Issue: 1
Pp: 102-111
Vu Tuan Kien, Le Huy Binh, Phan Hai Phong, Doan Thi Hien, Nguyen Thi Thuy My, Nguyen Hai Nam, Do Thi Thao, Michael Baltas and Tran Khac Vua
DOI: 10.2174/1570180813666160810155354



Antileishmanial Activity of Labdane Diterpenes Isolated from Alpinia nigra Seeds

Volume:14   Issue: 1
Pp: 119-124
Sudipta Ghosh, Rajesh Kumar Singh, Vikash Kumar Dubey and Latha Rangan
DOI: 10.2174/1570180813666160725100300