Letters in Drug Design & Discovery

Editor-in-Chief
K. Kuca
University of Hradec Kralove
Hradec Kralove
Czech Republic

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Volume:12   Issue: 2
Pp: 6-6

DOI: 10.2174/157018081202141120104517

Investigation of New Phenothiazine and Carbazole Derivatives as Potential Inhibitors of Human Farnesyltransferase

Volume:12   Issue: 2
Pp: 85-92
Gina-Mirabela Dumitriu, Alina Ghinet, Dalila Belei, Benoit Rigo, Philippe Gautret, Joelle Dubois and Elena Bicu
DOI: 10.2174/1570180811666140909010435


Mannich Base Derivatives as the Potential Candidates of Human Topoisomerase II Inhibitors

Volume:12   Issue: 2
Pp: 103-108
Huseyin Istanbullu, Muge Senarisoy, Ercin Erciyas and Zeki Topcu
DOI: 10.2174/1570180811666140901234507


Pd/C-catalyzed Synthesis of (E)-2-arylmethylideneindolin-3-ols Under Ultrasound: Their Initial Evaluation as Potential Anti-proliferative Agents

Volume:12   Issue: 2
Pp: 109-116
Ponugubati Radhakrishna Murthi, Namburi Suresh, Chekuri Sharmila Rani, Mandava Venkata Basaveswara Rao and Manojit Pal
DOI: 10.2174/1570180811666140819224103


Synthesis, in Vitro and in Vivo Anticancer Activity of Hybrids of 3- Hydroxy-indolin-2-one and 2,3-Dihydroquinolin-4(1H)-one

Volume:12   Issue: 2
Pp: 117-123
Lei Zhang, Jing Wang, Wen-Yun Li, Juan Xia, Jing Gao and Qi-Zheng Yao
DOI: 10.2174/1570180811666140909010017


A Divide-and-Conquer Strategy for the Prediction of Protein Contact Map

Volume:12   Issue: 2
Pp: 124-130
Cosme E. Santiesteban-Toca, Gerardo M. Casanola-Martin and Jesus S. Aguilar-Ruiz
DOI: 10.2174/1570180811666140909011206


4-Substituted-2-Methoxyphenol: Suitable Building Block to Prepare New Bioactive Natural-like Hydroxylated Biphenyls open access plus

Volume:12   Issue: 2
Pp: 131-139
Maria Antonietta Dettori, Davide Fabbri, Marina Pisano, Carla Rozzo, Giuseppe Palmieri, Alessandro Dessi, Roberto Dallocchio and Giovanna Delogu
DOI: 10.2174/1570180811666140915222343


Alzheimer's Disease Prevention and Use of Traditional Plant Medicines

Volume:12   Issue: 2
Pp: 140-151
Xiaogang Wang, Raphael Dubois and James David Adams Jr
DOI: 10.2174/1570180811666140819223819


Synthesis, Characterization and Microbial Activity of New Bisphenol-C Derivatives

Volume:12   Issue: 2
Pp: 152-157
Bhavin Babu Dhaduk, Chirag Bhupendra Patel and Parsotam Hari Parsania
DOI: 10.2174/1570180811666140915222545


Non-Classical Therapeutic Approach in the Treatment of Alzheimer's Disease: A Mini Review

Volume:12   Issue: 2
Pp: 158-164
Vladan Bajic, Biljana Spremo-Potparevic, Lada Zivkovic, Emina Sudar, Sonja Zafirovic, Milan Obradovic and Esma R. Isenovic
DOI: 10.2174/1570180811666140909010803