Letters in Drug Design & Discovery

Editor-in-Chief
K. Kuca
University of Hradec Kralove
Hradec Kralove
Czech Republic

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Modeling the Active Conformation of Human µ Opioid Receptor

Volume:11   Issue: 9
Pp: 1053-1061
Agnieszka A. Kaczor, Damian Bartuzi and Dariusz Matosiuk
DOI: 10.2174/1570180811666140322001506

Synthesis and In vitro Evaluation of Thiadiazole Derivatives as AChE, Bu- ChE and LOX Inhibitors

Volume:11   Issue: 9
Pp: 1062-1069
Mehlika Dilek Altintop, Ahmet Ozdemir, Usama Abu Mohsen, Halide Edip Temel, Gulsen Akal n Ciftci and Zafer Asim Kaplancikli
DOI: 10.2174/1570180811666140529004517

To Preliminarily Evaluate The Anticancer Activiy of 1,2-di(quinazolin-4- yl)diselane Against MDA-MB-435 Cells in vitro

Volume:11   Issue: 9
Pp: 1090-1095
Yinjiu Huang, Hong Xie, Gang Liu, Xiaomei Hu, Lin Su, Jianguo Hu, Qiyi Wang and Yibo Ding
DOI: 10.2174/1570180811666140617212723

Evaluation of Alkylating and Intercalating Properties of Mannich Bases for Cytotoxic Activity

Volume:11   Issue: 9
Pp: 1096-1106
Huseyin Istanbullu, Yalcin Erzurumlu, Petek Ballar Kirmizibayrak and Ercin Erciyas
DOI: 10.2174/1570180811666140529005029

Synthesis and Antifungal Activity of 1,3,4-Thiadiazole Derivatives Containing Pyridine Group

Volume:11   Issue: 9
Pp: 1107-1111
Lin-Jiong Zhang, Ming-Yan Yang, Zhao-Hui Sun, Cheng-Xia Tan, Jian-Quan Weng, Hong-Ke Wu and Xing-Hai Liu
DOI: 10.2174/1570180811666140610212731

Pharmacokinetic Modeling of Caco-2 Cell Permeability Using Genetic Programming (GP) Method

Volume:11   Issue: 9
Pp: 1112-1118
Renu Vyas, Purva Goel, M. Karthikeyan, S.S. Tambe and B.D. Kulkarni
DOI: 10.2174/1570180811666140610213438

Synthesis and Bioactivities of Novel 1,3,4-oxadiazole Derivatives Containing Pyridine Moiety

Volume:11   Issue: 9
Pp: 1119-1123
Guo-Xiang Sun, Yan-Xia Shi, Zhao-Hui Sun, Ming-Yan Yang, Hong-Ke Wu, Jian-Quan Weng, Cheng-Xia Tan, Xing-Hai Liu, Bao-Ju Li and Yong-Gang Zhang
DOI: 10.2174/1570180811666140522002929

Solvent-Free Synthesis and Insecticidal Activities of C6-Esterified Coumarins

Volume:11   Issue: 9
Pp: 1124-1132
Ying Xie, Zheng-Lin Lei and Yan-Ping Luo
DOI: 10.2174/1570180811666140603003043