Letters in Drug Design & Discovery

Editor-in-Chief:

George Perry
University of Texas
San Antonio, TX
USA

Back

Become EABM
Become Reviewer

Analysis of Proteasome Inhibition Prediction Using Atom-Based Quadratic Indices Enhanced by Machine Learning Classification Techniques

Volume:11   Issue:6
Pp: 705-711
Gerardo M. Casanola-Martin, Huong Le-Thi-Thu, Yovani Marrero-Ponce, Juan A Castillo- Garit, Francisco Torrens, Facundo Perez-Gimenez and Concepcion Abad
DOI: 10.2174/1570180811666140122001144

Design, Synthesis and Biological Evaluation of Some Oxadiazole Derivatives as Novel Amide-Based Inhibitors of Soluble Epoxide Hydrolase

Volume:11   Issue:6
Pp: 721-730
Elham Rezaee Zavareh, Mahdi Hedayati, Laleh Hoghooghi Rad, Azin Kiani, Soraya Shahhosseini, Mehrdad Faizi and Sayyed Abbas Tabatabai
DOI: 10.2174/1570180811666140220005530

A Potential Anticancer Agent 1,2-di(quinazolin-4-yl)diselane

Volume:11   Issue:6
Pp: 731-735
Yinjiu Huang, Gang Liu, Xiaomei Hu, Hao Liu, Jianguo Hu, Zhenzhong Feng, Bi Tang, Jun Qian, Qiyi Wang and Xuehui Long
DOI: 10.2174/1570180811666140214204858

Synthesis and Anti-Cancer Activities of Aryl Benzyl Ethers with Fluoro Substituents

Volume:11   Issue:6
Pp: 736-741
Yi Jiang, Hong Xu, Li Liu, Rui He, Xiaomei Song and Na Li
DOI: 10.2174/1570180811666140130232233

Anticancer Activity and DNA Binding of 4-Alkylenediamines Modified Naphthalimide Derivatives

Volume:11   Issue:6
Pp: 742-748
Ke-Rang Wang, Feng Qian, Zi-Bo Yang, Hong-Wei An, Dan Han, Hua Chen, Ping-Zhu Zhang and Xiao-Liu Li
DOI: 10.2174/1570180811666140121234834

Design, Synthesis and Biological Evaluation of 5-Amino-1H-pyrazole-4- carboxamide Derivatives as Potential Antitumor Agents

Volume:11   Issue:6
Pp: 749-755
Baowei Yang, Wukun Liu, Yicheng Mei, Dandan Huang, Hai Qian, Wenlong Huang and Ronald Gust
DOI: 10.2174/1570180811666140115234123

Synthesis of Novel Macrocyclic Tetraamides

Volume:11   Issue:6
Pp: 756-761
Barun Kumar Mehta, Dandela Rambabu, Guttikonda Raja, ASG. Prasad, Jim-Min Fang and Mandava Venkata Basaveswara Rao
DOI: 10.2174/1570180811666140116215724

Design, Synthesis and Biological Evaluation of 2, 4, 5-Triphenylimidazole Derivatives with Preliminary SAR

Volume:11   Issue:6
Pp: 762-769
Chunqi Hu, Jianfeng Shen, Kejun Bian, Ruoyu Zhang and Liping Deng
DOI: 10.2174/1570180811666140116214111

Pharmacokinetic Analysis of Tetramethylpyrazine Bis-Nitrone TN-2 in Rats and its Protein Binding In Vitro

Volume:11   Issue:6
Pp: 770-777
Yewei Sun, Kaiyi Liao, Sai Li, Zaijun Zhang, Pei Yu and Yuqiang Wang
DOI: 10.2174/1570180811666140121234608

Novel 4-Oxothienopyrimidinyl Propanoic Acid Derivatives as AMPActivated Protein Kinase (AMPK) Activators

Volume:11   Issue:6
Pp: 778-785
Pradip K. Sasmal, Mahaboobi Jaleel, P. Tirumala Rao, M. Munikumar, Megha Bhattacharya, Nutakki Ravi Kumar, Poondla. Neelima, Khaji Abdul Rawoof, P. Narasimha Rao, Chandrasekhar Abbineni, M. Roshaiah, S. Sridhar, Thammera Ranjith Kumar, Menon C. A. Vinu, Vijay Potluri, Parimal Misra, Rashmi Talwar and Saibal Kumar Das
DOI: 10.2174/1570180811666140122003044

Influence of the Preparation Method on the Dissolution Properties of Piroxicam - Cyclodextrins Systems

Volume:11   Issue:6
Pp: 786-808
F. Bouchal, M. Skiba, S. Fatmi, N. Chaffai and M. Lahiani-Skiba
DOI: 10.2174/1570180811666140207215957