Letters in Drug Design & Discovery

Editor-in-Chief
K. Kuca
University of Hradec Kralove
Hradec Kralove
Czech Republic

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Molecular Modulation of Muscarinic Antagonists. Synthesis and Pharmacological Profile of 2,2-diphenyl-2-ethylthioacetic and 3,3-diphenyl-3- ethylthiopropionic Acid Derivatives Characterized by a Dipeptide Spacer

Volume:1   Issue: 2
Pp: 91-96
S. Scapecchi, C. Martelli, P. Angeli, C. Bellucci, M. Buccioni, S. Dei, F. Gualtieri, G. Marucci, R. Matucci and M. N. Romanelli
DOI: 10.2174/1570180043485527

Quaternary Heteroarenium Salts as the Competitive Inhibitors of the Brain Acetylcholinesterase

Volume:1   Issue: 2
Pp: 97-100
Kamil Kuca, Jiri Cabal, Jiri Patocka and Vlastimil Dohnal
DOI: 10.2174/1570180043485509

Comparative Study of 3D-QSAR Techniques on Angiotensin II Receptor (AT1) Antagonists

Volume:1   Issue: 2
Pp: 115-120
P. A. Datar, E. C. Coutinho and Sudha Srivastava
DOI: 10.2174/1570180043485536

Diverse Peptidyl Privileged Structures as Potent Somatostatin Receptor Ligands

Volume:1   Issue: 2
Pp: 121-125
Alexander Pasternak, Yanping Pan, Ralph T. Mosley, Susan P. Rohrer, Elizabeth T. Birzin, James Schaeffer, Arthur A. Patchett and Lihu Yang
DOI: 10.2174/1570180043485563

Thalidomide as an Antiangiogenic Drug in the Treatment of Multiple Myeloma

Volume:1   Issue: 2
Pp: 135-136
Domenico Ribatti and Angelo Vacca
DOI: 10.2174/1570180043485491

Recombinant Murine Polyoma Virus-like-particles Induce Protective Antitumour Immunity

Volume:1   Issue: 2
Pp: 137-147
M. Brinkman, J. Walter, I. Jennes, M. Neugebauer, W. Bertling, S. Grein, M. Thies, M. Weigand, T. Beyer and M. Herrmann
DOI: 10.2174/1570180043485545

Steps towards Phage Display Libraries with an Extended Amino Acid Repertoire

Volume:1   Issue: 2
Pp: 163-167
M. Bjorklund and E. Koivunen
DOI: 10.2174/1570180043485572

Towards an Experimental de Novo Design Protocol. The use of Protein Crystallography to Deconvolute Dynamic Combinatorial Processes

Volume:1   Issue: 2
Pp: 173-177
Robert E. Babine, Michael J. Rynkiewicz, Lei Jin and Sherin S. Abdel-Meguid
DOI: 10.2174/1570180043485617

Grid-Based Hydrogen Bond Potentials with Improved Directionality

Volume:1   Issue: 2
Pp: 178-183
Ruth Huey, David S. Goodsell, Garrett M. Morris and Arthur J. Olson
DOI: 10.2174/1570180043485581