Letters in Drug Design & Discovery

Editor-in-Chief

K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

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Volume 17 - Issue 5



Meet Our Editorial Board Member promotion: free to download

Volume: 17   Issue: 5
Pp: 519-519
Romeo Romagnoli
DOI: 10.2174/157018081705200403080300



Bimetallic Catalyzed N-arylation Used in Synthesis of Novel β-carbolines Derivatives

Volume: 17   Issue: 5
Pp: 520-525
Rui Cai , Li Zhu, Pengfei Wang and Yu Zhao*
DOI: 10.2174/1570180815666181025124615



Design, Synthesis and Antifungal Activity of Novel 1-(Adamantan-1-yl) ethanone Oxime Esters

Volume: 17   Issue: 5
Pp: 526-532
Si Liu, Li-Zhi Niu, Yan-Hua Shi, Fu-Xian Wan and Lin Jiang*
DOI: 10.2174/1570180816666190329225307



Virtual Screening and In Silico Simulation Analysis for Rapid and Efficient Identification of Novel Natural GPR40 Agonist

Volume: 17   Issue: 5
Pp: 533-546
Virendra Nath, Rohini Ahuja and Vipin Kumar*
DOI: 10.2174/1570180815666180914162935



Diversified Thiazole Substituted Coumarins and Chromones as Non- Cytotoxic ROS and NO Inhibitors

Volume: 17   Issue: 5
Pp: 547-555
Uzma Salar, Khalid Mohammed Khan*, Almas Jabeen, Shafquat Hussain, Aisha Faheem, Farwa Naqvi and Shahnaz Perveen
DOI: 10.2174/1570180816666190611155218



Caffeic Acid Phenethyl Ester Effects: In Silico Study of its Osteoimmunological Mechanisms

Volume: 17   Issue: 5
Pp: 556-562
Yuhao Zhao, Xiaokun Pang, Akriti Nepal, Xincan Jiang, Xiaoxin Xu, Dongbin Zhao, Ghulam Murtaza* and Yanxu Ma*
DOI: 10.2174/1570180815666180803111902



(Substituted)-benzo[b]thiophene-4-carboxamide Synthesis and Antiproliferative Activity Study

Volume: 17   Issue: 5
Pp: 563-573
Chandrakant Dhondiram Pawar, Dattatraya Navnath Pansare and Devanand Baburao Shinde*
DOI: 10.2174/1570180815666181004114125



Design of New Therapeutic Agents Targeting FLT3 Receptor Tyrosine Kinase Using Molecular Docking and 3D-QSAR Approach

Volume: 17   Issue: 5
Pp: 585-596
Swapnil Pandurang Bhujbal, Seketoulie Keretsu and Seung Joo Cho*
DOI: 10.2174/1570180816666190618104632



Uses of Cyclohexan-1,3-dione for the Synthesis of Thiazole, Pyrazole, Thiophene, Isoxazole and Pyran Derivatives with Antitumor Activities

Volume: 17   Issue: 5
Pp: 597-609
Rafat Milad Mohareb, Nadia Youssef Megally Abdo* and Waleed Nabeel Al-darkazali
DOI: 10.2174/1570180816666190618115128



Synthesis and In Vitro Biological Activity Evaluation of Novel Imidazo [2,1-B][1,3,4] Thiadiazole as Anti-Alzheimer Agents

Volume: 17   Issue: 5
Pp: 610-617
Sara Azimi, Omidreza Firuzi, Aida Iraji, Afsaneh Zonouzi , Mahsima Khoshneviszadeh, Mohammad Mahdavi* and Najmeh Edraki*
DOI: 10.2174/1570180816666181108115510



Docking and 3D-QSAR Studies of Hydrazone and Triazole Derivatives for Selective Inhibition of GRK2 over ROCK2

Volume: 17   Issue: 5
Pp: 618-632
Seketoulie Keretsu, Swapnil Pandurang Bhujbal and Seung Joo Cho*
DOI: 10.2174/1570180816666190618105320



Microwave-assisted Synthesis and Docking Studies of Phenylureas as Candidates for the Drug Design Against the Biological Warfare Agent Yersinia Pestis

Volume: 17   Issue: 5
Pp: 633-639
Tanos Celmar Costa França*, Leonardo da Costa Bastos, Teobaldo Cuya, Mehdi Sirouspour, Franklin Chacón-Huete, David Bendahan and Pat Forgione*
DOI: 10.2174/1570180816666190710144212



Cytotoxic Activity and DNA Binding Property of New Aminopyrimidine Derivatives

Volume: 17   Issue: 5
Pp: 640-654
Hamidreza Akrami, Bibi Fatemeh Mirjalili, Omidreza Firuzi, Azadeh Hekmat, Ali Akbar Saboury, Ramin Miri, Omid Sabzevari, Morteza Pirali-Hamedani, Fereshteh Jeivad, Setareh Moghimi, Saeed Emami, Alireza Foroumadi* and Mehdi Khoobi*
DOI: 10.2174/1570180816666190712102119



Lead Molecules as Novel Aromatase Inhibitors: In Silico De Novo Designing and Binding Affinity Studies

Volume: 17   Issue: 5
Pp: 655-665
Laxmi Banjare, Sant Kumar Verma, Akhlesh Kumar Jain and Suresh Thareja*
DOI: 10.2174/1570180816666190703152659



Azacyanines as Novel Topoisomerase II Alpha Inhibitors

Volume: 17   Issue: 5
Pp: 666-671
Sercan Guloglu, Fahriye Nur Kirmaci, Özgül Persil Çetinkol*, Mehrdad Forough and Aybuke Gulkaya
DOI: 10.2174/1570180816666190628161945



Current Strategies and Approaches in Combating SARS-CoV-2 Virus that Causes COVID-19 promotion: free to download

Volume: 17   Issue: 5
Pp: 672-674
D. Sivaraman*, P. S. Pradeep, S. Sundar Manoharan, C. Ramachandra Bhat, K. V. Leela and V. Venugopal
DOI: 10.2174/157018081705200403092546