ISSN (Print): 1570-1808
ISSN (Online): 1875-628X
Volume 16, 12 Issues, 2019
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ISSN (Print): 1570-1808
ISSN (Online): 1875-628X
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Editor-in-Chief K. Kuca University of Hradec Kralove Hradec Kralove Czech Republic
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Special Issue Submission
"Letters in Drug Design & Discovery should be available in every library in the pharmaceutical industry and in universities."
R. F. Borne, Associate Director
Laboratory for Applied Drug Design and Synthesis, The University of Mississippi, USA
I would like to thank Bentham Science Publishers for their peerless effort to keep up scientists and students updated with the latest science and research work. Actually, Bentham assists researchers to achieve their goals to spread their reputation worldwide.
I have experienced sincere, efficient and effective communication while dealing with Bentham team members. I intend to submit my work to Bentham and try to pick up journals that match my research profile. I have submitted a recent work to Medicinal Chemistry and nowadays I am drafting a manuscript targeting Current Pharmaceutical Design. Honestly, no words neither sentences would express my gratefulness and admiration. Bentham has offered my institution three months trial to access their journal lists and surf on its Board. This free access trial fulfills my literature review and broadens my horizon to absorb the recent research in pharmaceutical sciences and medicinal chemistry. Finally, I wish Bentham more success and achievement!
Has contributed: CETP Inhibitory Activity of Chlorobenzyl Benzamides: QPLD Docking, Pharmacophore Mapping and Synthesis.
5 Abstract Ahead of Print are available electronically
77 Articles Ahead of Print are available electronically
The special issue entitled “Opportunities and Challenges in the Anticandidal Drug Discovery and Development” of Letters
in Drug Design & Discovery, consists of invited papers including research articles and reviews on recent trends in antifungal
drug discovery. The articles in this special issue enlighten the current anticandidal therapeutic approaches including natural
bioactive compounds, recent trends in anticandidal drug discovery using nanoparticles, and also synthetic compounds such as
The increasing incidence of serious fungal infections is a well-recognized problem. Among all fungi, Candia is
opportunistic pathogenic yeast which is responsible for the fourth leading cause of nosocomial infections. The treatment of
fungal infections has very limited therapeutic options as compared to bacterial infections. The emergence of drug resistance,
especially for the most successful antifungal class azole, is another worst situation associated with these infections.
The purpose of this special issue is mainly focusing on the challenges and new approach to develop better prototype
molecules which can be future therapy for Candidiasis. The anticandidal results of ethanolic extracts of Costus cf. arabicus on
Candida spp. provide an alternate with natural compound therapy over traditional antifungal agents . The research is also
important because the said natural compound is also effective against drug-resistant Candida strains. Nano-particles and their
use is highly exciting and fast-growing topic among researchers of all domains. Another article introduced and explored the
possible use of nano-particles in medicine . The paper emphasized the recent progress of nano-particles as anticandidal
agents, their advancement over conventional drugs and some novel nano-formulations with enhanced therapeutic efficacy.
Similarly, current scenario of development of azole based anticandidal agents has been described in a review article .
Moreover, the research published in this special thematic issue gives a basic understanding of ongoing research on anticandidal
agents and provide an opportunity to develop some better and alternative therapeutic agents for the treatment of Candida
Finally, I would like to acknowledge the efforts of all authors who contributed to this special issue by providing articles of
their high quality research. I also wish to extend my acknowledgement to the contribution of the editorial managers Ms. Aqsa
Hasan and Ms. Summaiya Ikram of “Letters in Drug Design & Discovery” who managed all the manuscripts.
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